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Australian Centre for Ancient DNA The University of Adelaide Australia
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Australian Centre for Ancient DNA
School of Earth & Environmental Sciences
THE UNIVERSITY OF ADELAIDE
SA 5005
AUSTRALIA
Email

Telephone: +61 8 8303 3952
Facsimile: +61 8 8303 4364

Postgraduate divisional scholarships (FOR AUSTRALIAN OR NEW ZEALAND RESIDENTS ONLY) commencing in 2009, now open. For expression of interest in any of the following projects, please apply here and include your CV/resume. International students should consult the International Student website for tuition fees and associated costs for PhD Candiature before applying. [ Visit website here] ·

PhD opportunities currently available at ACAD, new for 2010

We are looking for interested graduate students with a 1st Class Hons, who are highly motivated and enjoy independent and unusual research in the general areas below. An interest in evolution and natural history are key requirements, and a background in any of the following would be useful: evolution, genetics, molecular biology, chemistry/biochemistry, paleontology, archaeology, and anthropology.

International Students wishing to study at The University of Adelaide in 2010 should check the available scholarship opportunities here as they provide payment of full tuition fees plus an annual living allowance of approximately AUD$20,000 tax free. Note the closing date for these is generally in August of each year. The other alternative for international students to be able to study here is to obtain sponsorship from their respective country.

Postgraduate Opportunities in Environmental Genomics, Closing date 31 October, 2009
6 PhD projects in: Forensics, Water, Health, Conservation Biology, Antarctic biodiversity.

Six PhD projects are available in the field of Environmental Genomics, at the University of Adelaide starting in early 2010, working on an ARC LINKAGE funded project at the Australian Centre for Ancient DNA. Each project focuses on the application of targeted metagenomic assays to perform rapid biodiversity and taxonomy assessment on complex biological samples in the following fields;

  • Project 1) Forensics: Using the genetic content of soil samples to predict crime scene/source areas. Focusing on invertebrate, plant and animal signals. Project partners – Australian Federal Police
  • Project 2) Water Quality: Analysing the biodiversity of standard, desalinated and recycled/re-used water systems, focusing on the detection and identification of novel pathogens. Project partners – SA Water
  • Project 3) Mining/Conservation biology: Using environmental genomic methods to rapidly analyse plant, animal and invertebrate taxonomic biodiversity in soil samples from survey sites across South Australia. Project partner – Primary Industries Research South Australia, and Department of Environment and Heritage, SA
  • Project 4) Health: Developing metagenomic methods to detect and monitor known and novel pathogens in medical systems, focusing on point of care. Project partner – SA Pathology
  • Project 5) Antarctic biodiversity: Using environmental genomic approaches to analyse the biodiversity of Antarctic invertebrates using existing and field collected samples. Project partner: South Australian Museum
  • Project 6) Bioinformatics: Designing, programming and implementing software plug-ins for GENEIOUS, to allow the interface between environmental metagenomic data and end-users, including conservation, water and health managers. Project partners – Biomatters, NZ (producers of GENEIOUS).

The PhD projects are available to Australian and NZ citizens/permanent residents with a 1st class Honours degree.
Applicants will also be encouraged to apply for Australian postgraduate awards (closing date is Oct 31st) where applicable, refer to this website for the application process http://www.adelaide.edu.au/graduatecentre/scholarships/postgrad/pgresearch/apa.html.  International students are also invited to apply, although international course fees are likely to apply and you should consult the following International webpage before making enquiries. Closing date for International Scholarship applications is August 2010 and you should note the selection process is extremely competitive. Recent successful applicants for the research awards have usually had a research Masters, or a coursework Masters with a substantial research component, and an outstanding academic performance at an internationally recognised university. 

Enquires to Maria Lekis or Prof. Alan Cooper for further details.

Application of computational methods in the analysis of human evolution

The study will use both ancient and modern sequence data produced as part of the National Geographic Society 'Genographic Project'. The project will investigate the impact and applications of recent advances such as the rates curve (Ho et al. MBE 2005), paleodemographic reconstructions (Atkinson et al. MBE 2008) and other issues involved in the molecular dating of human migrations and population movements, and the relationship to environmental and climatic changes over the past 100-200 Kyr. The work will involve collaborations with archaeologists, palaeoenvironmentalists and other members of the Genographic Project.
Desirable background. Experience and a strong interest in computational biology, phylogenetics, population genetics and mathematics

aDNA studies of Liang Bua Cave, Flores

Genetic studies of sediments, rodent bones, and other biological signals such as stalactites from the home of the hobbits, Homo floresiensis, and surrounding sites on Flores and Sulawesi. In collaboration with Kira Westaway and Mike Morwood (U. Wollongong), Mike Gagan (ANU) and Jian-xin Zhao (UQ).

Desirable background. Evolution, ecology, climate/environmental change, sedimentology, stratigraphy, paleontology, fieldwork.

Naracoorte caves

A unique deposit of preserved rodent bones and possum droppings has been found in Blanche Cave, Naracoorte, which provide a detailed record of environmental changes in SE Australia over a 40 Kyr time period, recording the impacts of climate change, Aboriginal landscape use, the Last Glacial Maximum, Holocene warming and the impacts of Europeans and introduced pests.

Desirable background. Evolution, ecology, climate/environmental change, sedimentology, stratigraphy, paleontology, fieldwork.

Sediment DNA records of climate change and evolution

ACAD has a large collection of sediment samples from marine, lacustrine, and terrestrial (mostly cave) sites from around the world. This project involves recovering plant, animal and other genetic records to analyse climate and environmental change. It could be combined with the next project.

Desirable background. Sedimentology, stratigraphy, soil chemistry, biochemistry, ecology, paleontology, fieldwork.

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Antarctic ice

The ultra low temperatures of Antarctic sediment and ice deposits are perfect for long-term preservation of genetic records. Working with Antarctic researchers, this project will analyse the genetic records of microbes, plants, and marine organisms from both terrestrial and marine sediment samples. New technological approaches will be used to detect extremophiles, and the full genetic diversity of these environments.

Desirable background. Evolution, sedimentology, stratigraphy, polar research, fieldwork.

Yukon permafrost deposits

A detailed genetic and ecological study of the impacts of climate change on a deep frozen ecosystem spanning a 130kyr time frame. The study groups will be plants and small mammals, and this project will examine the biological and genetic responses of populations to major environmental change - such as migration, glacial refugia, local extinction, and invasions.

Desirable background. Evolution, sedimentology, stratigraphy, polar research, fieldwork.

Rates of evolution

This project will further explore the issues of temporal dependency of molecular rates, ie changes in the speed of the molecular clock according to the time period over which it is used. This largely computer-based analysis will explore new discoveries about why this effect occurs, and how it might be corrected to allow for accurate dating of major evolutionary events within human evolution, domestication, biogeography and epidemiology.

Desirable background. Evolution, computational biology, phylogenetics, population genetics

Using new aDNA approaches to improve forensic methods

New methods have recently been developed at ACAD to allow finescale analysis of ancient DNA molecules - including their length and amount and type of damaged positions, which would effect the accuracy of genetic typing. This new window into the way in which DNA degrades, and is affected by different types of environmental treatment (drying, washing, temperature, humidity etc) is of major importance for forensic studies. This project is in collaboration with several forensic groups, and the Australian Federal Police.

Desirable background. Molecular biology, chemistry, genetics, evolution, population genetics.

Studies of megafauna from the La Brea tar pits, Los Angeles

The La Brea tar pits, in the middle of Los Angeles, hold an amazing collection of well-preserved megafauna, including hundreds of thousands of bones of carnivores (wolves, bears, lions, saber-tooths etc). Many of the bones are extremely well-preserved, with extractable collagen and perfect morphological preservation - although they are deeply ingrained with tar. Recent studies at ACAD have demonstrated that it is possible to retrieve DNA from young specimens, and this has opened the way to largescale population level analyses of megafauna on a number of levels, ranging from phylogenetics to population genetics. Desirable background. Molecular biology, chemistry, evolution, population genetics.

Phylogeny and age of the New Zealand Acanthisittid wrens

The NZ wrens are the sister taxa to the passerines (song birds), which includes nearly 50% of all bird species. Their unique basal position means that they record the earliest characteristics of this group, and in addition they are one of the only large bird radiations in NZ. This project will reconstruct this phylogeny using ancient DNA, and analyse the timing of the radiation with respect to the Oligocene Drowning, a major genetic bottleneck in NZ's past.

Desirable background. Evolution, molecular biology, genetics, population genetics.

Rodent evolution, biodiversity and human migration in Australia and South East Asia

This collaborative study with Dr Ken Aplin, CSIRO, will use ancient DNA from the large numbers of rodent bones preserved in caves and archaeological sites throughout these areas to analyse rodent evolution, biodiversity and extinctions through time, in response to climate change and human habitat alteration. A key project will be to analyse Rattus rattus species complex, and to use this to trace the timing and nature of human migration patterns during the Neolithic. The project has the potential to allow a focus on evolution, population genetics, taxonomy, biodiversity, and archaeology.

Desirable background. Evolution, ecology, molecular biology, genetics, population genetics, fieldwork.

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