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Discipline of Obstetrics and Gynaecology
School of Paediatrics and Reproductive Health

The University of Adelaide

 

Women's and Children's Hospital

King William Road

North Adealide SA 5006

AUSTRALIA

 

Email
Phone: +61 8 8161 7619
Facsimile: +61 8 8161 7652

LIMIT: Limiting weight gain in overweight and obese women during pregnancy to improve health outcomes: a randomised trial.

ACTRN12607000161426

This trial has completed recruitment and followup is currently being undertaken.

The aims of this randomised controlled trial are to assess whether the implementation of a package of dietary and lifestyle advice to overweight and obese women during pregnancy to limit weight gain is effective in improving maternal, fetal and infant health outcomes.

Funding: NHMRC Project Grant 2008-2011; NIH Grant, 2008-2012; Channel 7 Children's Research Foundation Grant, 2010; Clive and Vera Ramaciotti Foundation Grant 2010.

Funding: NHMRC Project Grant, 2008-2011; NIH Grant, 2008-2012; Channel 7 Children's Research Foundation Grant, 2010; Clive and Vera Ramaciotti Foundation Grant 2010.
Chief Investigators: Professor Jodie Dodd, Professor Deborah Turnbull, Professor Gary Wittert, Dr Andrew McPhee, E/Professor Jeffrey Robinson, Professor Caroline Crowther, Professor Julie Owens, Professor Matthew Gillman 
Clinical Trial Coordinator: Ms Andrea Deussen
Email: limit@adelaide.edu.au
Phone:
Fax:
61 8 8161 7657
61 8 8161 7652
Address:

Contact Us

Collaborating Centres

SA - Women's and Children's Hospital, Adelaide
Flinders Medical Centre
Lyell McEwin Hospital

References

  • Dodd JM, Turnbull DA, McPhee AJ, Wittert G, Crowther CA, Robinson JS. Limiting weight gain in overweight and obese women during pregnancy to improve health outcomes: the LIMIT randomised controlled trial. BMC Pregnancy Childbirth 2011;11.
  • Dodd JM, Grivell RM, Nguyen AM, Chan A, Robinson JS. Maternal and perinatal health outcomes by body mass index category. Aust N Z J Obstet Gyn 2011;51(2):136-140.
  • Dodd JM, Robinson JS. Gestational weight loss in overweight and obese women is associated with an increased risk of small for gestational age infants. Evid Based Med. 2011;16(4):156-6.
  • Dodd JM, Grivell RM, Crowther CA, Robinson JS. Antenatal interventions for overweight or obese pregnant women: a systematic review of randomised trials. BJOG 2010;117:1316-1326.
  • Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, et al. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. New England Journal of Medicine 2005;352(24):2477-2486.
Obesity is a significant health issue for women during pregnancy and childbirth, with estimates suggesting that 40% of women aged between 25 and 35 years are overweight or obese. There are well documented risks associated with obesity during pregnancy and childbirth. Maternal complications include hypertensive conditions and pre-eclampsia, gestational diabetes, infection, thromboembolic events, need for induction of labour, caesarean section and perinatal death. Infants of mothers who are overweight or obese are more likely to be macrosomic, require admission to the neonatal intensive care unit, be born preterm, have a congenital anomaly, and to require treatment for jaundice or hypoglycaemia. While there is an extensive body of literature related to defining the problems and potential complications associated with obesity during pregnancy and childbirth, there is a lack of information available related to effective interventions that may be implemented to improve maternal, fetal and infant health outcomes.