Our research in allergy and genetic immunology

Our research in allergy and genetic immunology aims to understand how the immune system is programmed before and after birth at the cellular, molecular and genetic level, and the role this programming plays in the subsequent development of disease. We are particularly interested in how genetics contribute to the way the body responds to bacteria, and why good immune systems turn bad and cause autoimmune conditions such as type 1 diabetes, cystic fibrosis, severe allergies and respiratory illnesses.

Using protein, lipid and DNA technology, we are attempting to identify the early genetic markers of disease and learn more about the factors that govern susceptibility and resistance to disease. We then hope to use this information to generate new ways of diagnosing, treating and preventing debilitating genetic conditions.

To date our research has uncovered genes that play a critical role in the early development of the immune system, which has in turn helped us pioneer several peptide and lipid-based drugs to combat autoimmune diseases.

Our position within SA Pathology enables the rapid translation of research findings into tertiary services. We collaborate closely with the Autoimmune Diseases Stream at the Children's Research Centre and actively contribute to immunological research and education at the University of South Australia, Flinders University and the Telethon Institute for Child Health at the University of Western Australia.