BIOCHEM 3125 - Advanced Molecular Biology IIIA (Biochemistry)
General Course Information
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Course Details
| Course Code | BIOCHEM 3125 |
| Course | Advanced Molecular Biology IIIA (Biochemistry) |
| Coordinating Unit | School of Molecular & Biomedical Science, Faculty of Sciences |
| Term | Semester 1 |
| Mode | Internal |
| Level | Undergraduate |
| Location/s | North Terrace |
| Units | 3 |
| Contact | Up to hours 14 per week |
| Prerequisites | BIOCHEM 2510, BIOCHEM 2520, BIOCHEM 2504 & BIOCHEM 2505 |
| Corequisites | Not applicable |
| Incompatible | BIOCHEM 3000 & BIOCHEM 3230 |
| Assumed Knowledge | Not applicable |
| Restrictions | Not applicable |
| Quota | Not applicable |
| Course Description | This course aims to extend the discussions of protein structure and function beyond Biochemistry Level II courses to gain a better understanding of the essential processes of molecular biology. Two principle themes are covered. 1. Protein Structure and Function: topics include structure and function of different classes of proteins, protein folding, targeted protein degradation, development of new therapies, molecular interactions and recognition. 2. Control of Gene Expression: topics include genetic circuits and synthetic biology; chromatin structure and remodelling during transcription; recruitment and assembly of transcription factors and the RNA polymerase complex; manipulating gene expression using "designer genes" and synthetic transcription factors; eukaryote mRNA synthesis, processing, modification, stability and translation, and manipulation of these processes to effect selective gene expression. This course combines lectures and tutorials from Molecular and Structural Biology III with molecular biology focussed laboratory placements in professional research laboratories or practical exercises in the first six weeks of the semester. The final six weeks include specialised Problem Based Learning (PBL) exercises designed to provide a perspective of how cutting edge biochemical principles and techniques are applied to major research questions in molecular biology. The importance of cross disciplinary approaches in modern biomedical research will be illustrated. |
Detailed Course Information
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