Anand Ganesan

Biography/ Background

Dr Anand Ganesan is a postdoctoral fellow at the Centre for Heart Rhythm Disorders, University of Adelaide, and electrophysiology fellow at the Royal Adelaide Hospital.  Dr Ganesan graduated from the University of Sydney, Australia, in 2000. He completed his PhD in basic cardiac electrophysiology at Johns Hopkins University, under the mentorship of Professor Brian O'Rourke from 2001-6. He went on to complete his internal medicine and cardiology training at Westmead Hospital, Sydney, Australia from 2006-10. He has been in his current position since January, 2011. Dr Ganesan’s research interests included evidence-based practice in electrophysiology, and atrial fibrillation mapping and ablation. His current mentor is Prof Prash Sanders.

 

Qualifications

ACADEMIC QUALIFICATIONS

 

1.      2013- CEPS-Certification in Clinical Cardiac Electrophysiology (International Board of Heart Rhythm Examiners)

 

2.      2010- FRACP (Fellowship of Royal Australasian College of Physicians).

 

3.      2006-  PhD, Johns Hopkins University. Supervisor: Professor Brian O’Rourke. Thesis title: Reconstitution of Excitation-Contraction Coupling by Reverse Engineering of Cardiac Myocytes with L-type Calcium Channel a1 subunits.

 

4.      2000- MBBS (Honours), University of Sydney.

 

 

 

 

 

 

 

 

Awards & Achievements

 1.      2012-HEART RHYTHM SOCIETY Young Investigator Award First Prize (Clinical). 
Project Title: “Shannon entropy localizes the pivot of rotors: implications for ablation.” Mentor: Prof Prashanthan Sanders.
 
2.      2012-ASIA-PACIFIC HEART RHYTHM SOCIETY-Young Investigator Award First Prize (Basic Science). Project Title-“Shannon entropy-a novel tool to localize the pivot of atrial fibrillation rotors.” Mentor: Prof Prashanthan Sanders.
 
3.      2012-HEART RHYTHM SOCIETY-Michel Mirowski International Postdoctoral Fellowship Award. 
 
4.      2012-HEART RHYTHM SOCIETY-Travelling scholarship to attend HRS Scientific Sessions, Boson, MA.
 
5.      2012- SOCIETY OF CARDIOVASCULAR MAGNETIC RESONANCE (SCMR), Young Investigator Award Finalist. Project Title: “Interactive real-time mapping and ablation of the pulmonary veins and cavotricuspid isthmus with an externally-irrigated MRI-compatible ablation catheter.” Mentor: Prof Prashanthan Sanders, Prof Joseph Selvanayagam.
 
6.      2012- SOCIETY of CARDIOVASCULAR MAGNETIC RESONANCE (SCMR)- Regional Scholarship for Australia and New Zealand
 
7.      2012- SA HEART Research and Education Foundation Award.
 
8.      2003-2005– AMERICAN HEART ASSOCIATION Predoctoral Research Fellowship.
 
9.      2001-2– JOHNS HOPKINS UNIVERSITY- University Scholarship.
 
10.  2000 DOUGLAS COHEN PRIZE - Best piece of surgical research by a medical student, University of Sydney.
 
11.  1998 - NATIONAL HEART FOUNDATION SCHOLARSHIP - vacation research scholarship.
 
12.  1997 - AUSTRALIAN KIDNEY FOUNDATION SCHOLARSHIP - vacation research scholarship.
 
13.  1993 - AUSTRALIAN STUDENTS PRIZE – Commonwealth government award for academic performance in the Higher School Certificate. HSC TER 99.90.
 
14.  1988-1993 - SYLVIA WEIGALL-CHASE SCHOLARSHIP – Academic scholarship to attend Sydney Grammar School.

Research Funding

 

FUNDING AS CHIEF INVESTIGATOR
1. 2012-13-Michel Mirowski International Fellowship, Heart Rhythm Society. Chief Investigator. $US 50 000. Project Title: Entropy Based Mapping in Human Atrial Fibrillation

2. 2011- Mary Overton Award, Royal Adelaide Hospital. Chief Investigator. $AU 35 000: Project Title: Basket catheter mapping in atrial fibrillation.

3. 2011- Tom Simpson Trust Fund, National Heart Foundation. Chief Investigator. $AU 15 000. Project Title: Western Blotting and mRNA Workstation.

4. 2011- Pfizer Cardiovascular Lipid Award. Chieft Investigator. $ AU 50000. Project Title: Identifying Organisation in the Chaos of Atrial Fibrillation.

4. 2003-5 American Heart Association Predoctoral Fellowship Award.

 

 

 

 

Publications

 

1.         Ganesan AN, Kuklik P, Lau DH, Brooks AG, Baumert M, Lim WW, Thanigaimani S, Nayyar S, Mahajan R, Kalman JM, Roberts-Thomson KC, Sanders P. Bipolar electrogram shannon entropy at sites of rotational activation: Implications for ablation of atrial fibrillation. Circulation Arrhythm Electrophysiol. 2013;6:48-57

2.         Nayyar S, Ganesan AN, Brooks AG, Sullivan T, Roberts-Thomson KC, Sanders P. Venturing into ventricular arrhythmia storm: A systematic review and meta-analysis. Eur Heart J. 2013;34:560-571

3.         Ganesan AN, Shipp NP, Brooks AG, Kuklik P, Lau DH, Lim HS, Sullivan T, Roberts-Thomson KC, P. S. Long term outcomes of catheter ablation of atrial fibrillation: A systematic review and meta-analysis Journal of the American Heart Assocation 2013;2:e004549. http://jaha.ahajournals.org/content/2/2/e004549.full

4.         Ganesan AN, Selvanayagam JB, Mahajan R, Grover S, Nayyar S, Brooks AG, Finnie J, Sunnarborg D, Lloyd T, Chakrabarty A, Abed HS, Sanders P. Mapping and ablation of the pulmonary veins and cavo-tricuspid isthmus with an mri compatible externally-irrigated ablation catheter and integrated electrophysiology system. Circ Arrhythm Electrophysiol. 2012;112.974436 e-published ahead of print.

5.         Ganesan AN, Brooks AG, Roberts-Thomson KC, Lau DH, Kalman JM, Sanders P. Role of av nodal ablation in cardiac resynchronization in patients with coexistent atrial fibrillation and heart failure a systematic review. Journal of the American College of Cardiology. 2012;59:719-726

6.         Brooks AG, Rangnekar G, Ganesan AN, Salna I, Middeldorp ME, Kuklik P, Baumert M, Roberts-Thomson KC, Sanders P. Characteristics of ectopic triggers associated with paroxysmal and persistent atrial fibrillation: Evidence for a changing role. Heart Rhythm Society. 2012;9:1367-1374

7.         Mahajan R, Brooks AG, Sullivan T, Lim HS, Alasady M, Abed HS, Ganesan AN, Nayyar S, Lau DH, Roberts-Thomson KC, Kalman JM, Sanders P. Importance of the underlying substrate in determining thrombus location in atrial fibrillation: Implications for left atrial appendage closure. Heart. 2011;98:1120-1126

8.         Ganesan AN, Wu G, Liou K, Pouliopoulos J, Barry MA, Thomas SP. Evaluation of noncontact mapping by comparison with simultaneous multisite contact recordings in acute ischemic ventricular fibrillation. Journal of Cardiovascular Electrophysiology. 2011;22:334-339

9.         Chong JJH, Ganesan AN, Eipper V, Kovoor P. Comparison of left ventricular ejection fraction and inducible ventricular tachycardia in st-elevation myocardial infarction treated by primary angioplasty versus thrombolysis. American Journal of Cardiology. 2008;101:153-157

10.       Maack C, Cortassa S, Aon MA, Ganesan AN, Liu T, O'Rourke B. Elevated cytosolic na+ decreases mitochondrial ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes. Circulation Research. 2006;99:172-182

11.       Ganesan AN, Maack C, Johns DC, Sidor A, O'Rourke B. Beta-adrenergic stimulation of l-type ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of (alpha)1c but not serine 1928. Circulation Research. 2006;98:e11-e18

12.       Maack C, Ganesan A, Sidor A, O'Rourke B. Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites. Circulation Research. 2005;96:91-99

13.       Ganesan AN, O'Rourke B, Maack C, Colecraft H, Sidor A, Johns DC. Reverse engineering the l-type ca2+ channel (alpha)1c subunit in adult cardiac myocytes using novel adenoviral vectors. Biochemical and Biophysical Research Communications. 2005;329:749-754

14.       Ganesan A, Smith GH, Broome K, Steinberg A. Congenital adrenal hyperplasia: Preliminary observations of the urethra in 9 cases. The Journal of Urology. 2002;167:275-278; discussion 278-279

15.       Johnson DW, Saunders HJ, Brew BK, Ganesan A, Baxter RC, Poronnik P, Cook DI, Gyory AZ, Field MJ, Pollock CA. Human renal fibroblasts modulate proximal tubule cell growth and transport via the igf-i axis. Kidney International. 1997;52:1486-1496

Professional Interests

Atrial Fibrillation - Mapping

Atrial Fibrillation- Clinical Outcomes Research

 

Entry last updated: Thursday, 16 May 2013