Associate Professor Gerald Atkins

Biography/ Background

Since graduating with a PhD from the University of Adelaide in 1998, Gerald Atkins developed a strong interest in bone biology, metabolism and disease. As Head of the Bone Cell Biology Group, Discipline of Orthopaedics and Trauma, University of Adelaide, he runs an integrated research program into the biology of osteoclasts, osteoblasts and osteocytes. He also has an ongoing interest in bone tumour biology, including osteosarcoma, giant cell tumour of bone and multiple myeloma. The group is also studying the biology of orthopaedic problems, such as aseptic loosening and fracture. He has published more than 70 papers related to bone remodelling. His research has attracted more than $7million in competitive research funding. A/Prof Atkins is also the Post-graduate Coordinator for the Discipline of Orthopaedics and Trauma.

Click here to read an interview with Gerald Atkins.

Publications

2011 - 2012

Findlay DM, Atkins GJ (2012) Mammals and minerals: a story of lactation and lacunae. (Invited Commentary) IBMS BoneKEy 9: Article number 140. doi:10.1038/bonekey.2012.140

Atkins GJ and Findlay DM (2012) Osteocyte regulation of bone mineral: a little give and take. Osteoporosis International 23(8):2067-2079. (Invited Review)

Atkins GJ, Haynes DR, Howie DW, Findlay DM. (2011) The role of polyethylene particles in peri-prosthetic osteolysis: a review. World Journal of Orthopaedics 2(10):93-101. doi:10.5312/wjo.v2.i10.1 (Invited Review)

Findlay DM and Atkins GJ. (2011) Relationship between serum RANKL and the expression of RANKL mRNA in bone. Osteoporosis International 22(10):2597-2602 (review).

Atkins GJ, Findlay DM, Anderson PH, Morris HA. (2011) Book Chapter: ‘Target genes: bone proteins' In ‘Vitamin D, Third Edition.' Feldman D. et al, Eds. Elsevier Academic Press, New York.

Findlay DM and Atkins GJ. (2011) TWEAK and TNF regulation of sclerostin: a novel pathway for the regulation of bone remodelling. In ‘Advances in TNF Family Research'. Advances in Experimental Medicine and Biology Vol 169. (Invited Review). Wallach, David; Kovalenko, Andrew; Feldmann, Marc (Eds.) Springer, New York, NY. Pp 337-348.

Kumarasinghe DD, Sullivan T, Kuliwaba J, Fazzalari NL, Atkins GJ (2012). Evidence for the dysregulated expression of TWIST1, TGFβ1 and SMAD3 in osteoblasts derived from patients with primary hip osteoarthritis. Osteoarthritis and Cartilage 20:1357-1366.

Alias E, Dharmapatni ASSK, Holding C, Atkins GJ, Findlay DM, Howie DW, Crotti TN, Haynes DR (2012) Polyethylene particles stimulate osteoclasts in vivo and in vitro in association with enhanced expression of ITAM-related molecules. Acta Biomaterialia 8:3104-3112.

Gulati K, Sinn Aw M, Ramakrishnan S, Atkins GJ, Findlay DM, Losic D. (2012) Polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion. Acta Biomaterialia 8:449-456.

Wijenayaka AR, Kogawa M, Lim HP, Bonewald LF, Findlay DM, Atkins GJ. (2011) Sclerostin promotes osteocyte support of osteoclast activity by a RANKL-dependent pathway. PLoS ONE 6(10): e25900. doi:10.1371/journal.pone.0025900

Dharmapatni AASSK, Smith MD, Holding CA, Weedon H, Zannettino AC, Zheng TS, Findlay DM, Atkins GJ*, Haynes DR*. (2011) The Relationship Between TWEAK and Fn14 Expression and the Pathogenesis of Joint Inflammation and Bone Erosion in Rheumatoid Arthritis. Arthritis Research Therapy. 13(2):R51.*Equal senior authors.

Atkins GJ, Rowe PS, Lim HP, Welldon KJ, Ormsby R, Wijenayaka AR, Zelenchuk L, Evdokiou A, Findlay DM. (2011) Sclerostin is a locally acting regulator of late-osteoblast/pre-osteocyte differentiation and regulates mineralization through a MEPE-ASARM dependent mechanism. Journal of Bone and Mineral Research 26(7):1425-36.

 

Files

• Interview - Gerald_Atkins_Interview.pdf [337.8K] (application/pdf)

Entry last updated: Saturday, 13 Apr 2013