Professor Mark Bartold

Qualifications

I received my Bachelor of Dental Surgery from the University of Adelaide in 1979. In 1980 I received my Bachelor of Science in Dentistry with First Class Honours and in 1983 graduated Doctor of Philosophy. I qualified for Fellowship of the Royal Australasian College of Dental Surgeons in the Special Stream of Periodontics in 1991. In 1996 I qualified for the degree of Doctor of Dental Science on the basis of a collection of published research papers. I am a Fellow of the Academy of Dentistry International and the International College of Dentists.

Teaching Interests

I am the current supervisor of the Doctor of Clinical Dentistry (Periodontics) postgraduate training program. A course information booklet can be found below.

Research Interests

I am principally interested in the connective tissues of the periodontium and their role in health, disease and regeneration. In particular our focus is on the role that proteoglycans play in these tissues.

Current active areas of research include:

1. Tissue engineering of Periodontal Matrices using cell seeding into bioresorbable matrices. This includes specific studies on the role of matrix components in the regeneration of periodontal structures.
2. Effect of various growth factors on proteoglycan synthesis. Using cell culture, northern hybridisation, PCR and immunohistochemical techniques.
3. An in vitro assessment of the cells involved in periodontal regeneration. This study involves extensive cell culture work and a variety of methods to determine fibroblast phenotype characteristics.
4. Development of the periodontal ligament and other components of the periodontium. Using a rat model we are principally studying the localisation and expression of a variety of growth factors in the developing periodontium
5. The expression of various proteoglycans by lymphocytes.
6. The relationship between periodontitis and rheumatoid arthritis.

Main areas of Research Interest are:

Periodontal Diseases
Connective Tissue Biochemistry
Proteoglycans
Acute & Chronic Inflammation
Lymphocyte function
Neutrophil Function
Immunopathology
Rheumatoid Arthritis

Publications

Rincon JC, Young WG, Bartold PM. The epithelial cell rests of Malassez - a role in periodontal regeneration? Journal of Periodontal Research 41: 245-252; 2006.

Ivanovski S, Gronthos S, Shi S, Bartold PM. Stem cells in the periodontal ligament. Oral Diseases 2006 12: 358-363; 2006.

Bartold, PM, Xiao Y, Lyngstaadas SP, Paine ML, Snead ML. Principles and applications of cell delivery systems for periodontal regeneration. Periodontology 2000 41: 123-135; 2006.

Slavkin HC, Bartold PM. Challenges and potential in tissue engineering. Periodontology 2000 41: 9-15; 2006.

Kong LX, Peng Z, Li S-D, Bartold. Nanotechnology and its role in the management of periodontal diseases. Periodontology 2000 40: 184-196; 2006.

PM Bartold, S Shi, S Gronthos. Stem Cells and Periodontal Regeneration. Periodontology 2000 40: 164-172; 2006.

PM Bartold, AS Narayanan. Molecular and Cell Biology of Healthy and Diseased Periodontal Tissues. Periodontology 2000 40: 29-49; 2006.

Bartold PM. Periodontal tissues in health and disease. Periodontology 2000 40: 7-10; 2006.

Rincon JC, Xiao Y, Young WG, Bartold PM. Enhanced proliferation, attachment and osteopontin expression of porcine periodontal cells with Emdogain. Archives of Oral Biology 50: 1047-1054; 2005.

Bartold PM, Marshall RI, Haynes DR. Periodontitis and rheumatoid arthritis. A Review. Journal of Periodontology 76: 2066-2074; 2005.

Hoffman A, Marshall RI, Bartold PM. Use of the Vector scaling unit in supportive periodontal therapy: A subjective patient evaluation. Journal of Clinical Periodontology 32: 1089-1093; 2005.

Rincon JC, Xiao Y, Young WG, Bartold PM. Production of osteopontin by cultured porcine epithelial cell rests of Malassez. Journal of Periodontal Research 40: 417-426; 2005.

Shi, S, Bartold PM, Miura M, Seo BM, Robey PG, Gronthos S. The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthopedics and Craniofacial Research 8: 191-199; 2005.

Georgiou TO, Marshall RI, Bartold PM. Prevalence of systemic diseases in Brisbane general and periodontal practice patients. Australian Dental Journal 49: 177-184; 2004.

Seo B-M, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, Young M, Robey PG, Wang C-Y, Shi S. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet. 364: 149-155; 2004.

Qian H, Xiao Y, Bartold PM. Immunohistochemical localization and expression of fibromodulin in adult rat periodontium and inflamed human gingiva. Oral Diseases. 10: 233-239; 2004.

Xiao Y, Bartold PM Modulating Effect of Serum on the Stimulation of Plasminogen Activator Inhibitor 2 Production in Human Gingival Fibroblasts by Lipopolysaccharide and Interleukin-1. Journal of the International Academy of Periodontology. 6: 81-88; 2004.

Xiao, Y, Haase, H, Young WG, Bartold PM. Development and transplantation of a mineralized matrix formed by osteoblasts in vitro for bone regeneration. Cell Transplantation 13: 15-25; 2004.

Bartold PM. Periodontal disease and health. Hygiene Today June: 4-10; 2003.

Bartold PM. Medication induced gingival overgrowth. Australian Dental Association (SA Branch) Newsletter 16 (May): 13-14; 2003.

Matias MA, Li H, Young WG, Bartold PM. Immunohistochemical localisation of extracellular matrix proteins in the periodontium during cementogenesis in the rat molar. Archives of Oral Biology 48: 709-716; 2003.

Bartold PM. Macromololecules in periodontal wound healing (invited article). Journal de Paradontologie d'Implantologie Orale. 22: 259-261; 2003.

Professional Associations

I am the current Editor of the Australian Dental Journal and member of the Editorial Board on the following Journals:

Journal of Periodontal Research, Australian Dental Journal, Oral Diseases, Clinical Oral Implants Research, Journal of the International Academy of Periodontology, Implant Dentistry Monitor, Clinical Implant Dentistry & Related Research, Journal of Periodontology

I am a member of the following organisations:

International Association for Dental Research, Matrix Biology Society of Australia and New Zealand, Australian Dental Association, Australian Society for Periodontology, Periodontal Research Group of IADR, Australia and New Zealand Academy of Periodontists, Federation Dentaire Internationale, Royal Australasian College of Dental Surgeons, Asian Pacific Society of Periodontology, Academy of Dentistry International, Australian Periodontology Research Foundation, New York Academy of Sciences, International Academy of Periodontology, International College of Dentists

Files

• DClinDent Periodontics Candidate Information - periobooklet.pdf [78.9K] (application/pdf)

Expertise for Media Contact

Categories	Dentistry
Expertise	Connective tissue research; tissue engineering; implants
Notes	Alt phone: (08) 8303 3437

Entry last updated: Sunday, 15 Nov 2009