Ms Melissa Cantley

Telephone	+61 8 8313 5388
Position	PhD Student
Email	melissa.cantley@adelaide.edu.au
Fax	+61 8 8313 4408
Building	Medical School North
Floor/Room	3 15a
Campus	North Terrace
Org Unit	Pathology

To link to this page, please use the following URL:
http://www.adelaide.edu.au/directory/melissa.cantley

Biography/ Background

BHlthSc (Hons)
Discipline of Anatomy and Pathology Postgraduate Student Representative for 2011

In 2006, Melissa completed a Bachelor of Health Sciences at the University of Adelaide followed by Honours (First Class) in Pathology in 2007. To expand on her knowledge in the area of localized pathological bone loss she worked as an NHMRC funded Research Assistant for two years. During this time Melissa helped establish a number of animal models of pathogenic bone loss, including periodontitis, rheumatoid arthritis and peri-implant osteolysis. Additional to this she optimized quantitative methods to assess bone loss using live micro CT scanning.

Melissa is currently completing her PhD within the Discipline of Anatomy and Pathology, School of Medical Sciences at the University of Adelaide with the support of an Australian Postgraduate Award. Her research is being undertaken in the Bone and Joint Laboratory with the supervision of Associate Professor David Haynes and Professor Mark Bartold. The overall aim of her PhD project is to investigate novel treatments of localized bone loss in chronic inflammatory diseases such as periodontitis, rheumatoid arthritis and prosthetic osteolysis.

Publications

Cantley MD, Bartold PM, Marino V, Reid RC, Fairlie P, Wyszynski RN, Zilm P, Haynes DR. (2009). The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A2 inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. J Periodontal Res. 44(3):317-22.
Cantley MD, Smith MD, Haynes DR. (2009). Pathogenic bone loss in rheumatoid arthritis: mechanism and therapeutic approaches. International Journal of Clinical Rheumatology. 4(5).
Bartold PM, Cantley MD, Haynes DR. (2010). Mechanisms and Control of Pathologic Bone loss in Periodontitis. Periodontology 2000. 53:55-69.
Bartold PM, Marino V, Cantley MD, Haynes DR. (2010). Effect of P. gingivalis-induced inflammation on development of rheumatoid arthritis. J Clin Periodontol. 37(5):405-11.
Cantley MD, Fairlie DP, Bartold PM, Rainsford KD, Le GT, Lucke AJ, Holding CA, Haynes DR. (2011) Compounds that inhibit histone deacetylases in class I and class II effectively suppress human osteoclasts in vitro. Journal of Cellular Physiology; 22: 22684.
Cantley MD, Haynes DR, Marino V, Bartold PM. (2011) Pre-existing periodontitis exacerbates experimental arthritis in a mouse model. J Clin Periodontol. 38(6):532-41.
Cantley MD, Bartold PM, Marino V, Fairlie DP, Le GT, Lucke AJ, Haynes DR. (2011) Histone deacetylase inhibitors suppress bone loss in experimental periodontitis. J Periodontal Res. Accepted 24 May 2011.

Entry last updated: Monday, 11 Jul 2011

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