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Further Enquiries
North Terrace Campus
Level 2, Molecular Life Sciences
The University of Adelaide
SA 5005
AUSTRALIA
Frank Grützner

Telephone: +61 8 8303 4812
Facsimile: +61 8 8303 4362

Publications

43. Warren WC, Hillier LW, Marshall Graves JA,  Birney E, Ponting CP, Grützner F, Belov K, Miller W, et al. (2008) Genome analysis of the platypus reveals unique signatures of evolution, Nature, May 8;453(7192):175-83..

42. Murchison E, Kheradpour P, Sachidanandam R, Smith C, Hodges E, Xuan Z, Kellis M, Grützner F, Stark A, and Hannon GJ (2008) miRNA and piRNA pathways in platypus and echidna. Genome Research, 7 May. [Epub ahead of print].

41. Wakefield MJ, Anderson M, Chang E, Wei K-J, Kaul R, Marshall Graves JA, Grützner F, Deeb SS, (2008) Cone Visual Pigments of Monotremes: Duplication, Loss and Recycling in mammals. Visual Neuroscience, accepted (January 2008).

40. Schmitz J, Zemann A, Churakov G, Timmermann B, Grützner F, Reinhard R and Brosius J, (2008) Retroposed SNOfall - A mammalian-wide comparative description of platypus snoRNAs, Genome Research, 7 May. [Epub ahead of print].

39. Veyrunes F, Waters P, Miethke P, Rens W, McMillan D, Alsop AE, Grützner F, Deakin JE, Whittington C, Schatzkamer K, Kremitzki CL, Graves T, Ferguson-Smith MA, Warren W, Marshall Graves JA, (2008) Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes, Genome Research, 7 May. [Epub ahead of print].

38. McMillan D, Miethke P, Alsop AE, Rens W, O'Brien P, Trifonov V, Veyrunes F, Schatzkamer K, Kremitzki CL, Graves T, Warren W, Grützner F, Ferguson-Smith MA, Graves JA (2008). Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus). Chromosome Res. 15(8):961-74.

37. Wallis MC, Waters PD, Delbridge ML, Kirby PJ, Pask AJ, Grützner F, Rens W, Ferguson-Smith MA, Graves JA. (2008). Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes. Chromosome Res. 15(8):949-59.

36. Rens W, O'Brien PC, Grützner F, Clarke O, Graphodatskaya D, Tsend-Ayush E, Trifonov VA, Skelton H, Wallis MC, Johnston S, Veyrunes F, Graves JA, Ferguson-Smith MA (2007). The multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian Z. Genome Biology. Nov 16;8(11):R243 [Epub ahead of print]. IF: 7.1, highly accessed.

35. Dohm, JC, Tsend-Ayush E, Reinhardt R, Grützner, Himmelbauer H. (2007). Disruption and pseudoautosomal localization of the Major Histocompatibility Complex in monotremes. Genome Biology 8, R175 (in press, published online 29/08/07). IF: 7.1

34. Wallis MC, Delbridge ML, Pask AJ, Alsop AE, Grützner, O'Brien PC, Rens W, Ferguson-Smith MA, Graves JA. Mapping platypus SOX genes; autosomal location of SOX9 excludes it from sex determining role. Cytogenet Genome Res. 2007;116(3):232-4. IF: 1.9

33. El-Mogharbel N, Wakefield M, Deakin JE, Tsend-Ayush E, Grützner F, Alsop A, Ezaz T, Marshall Graves JA. (2007). DMRT gene cluster analysis in the platypus: new insights into genomic organization and regulatory regions. Genomics. 89(1):10-21. IF: 3.5

32. Sankovic N, Delbridge ML, Grützner F, Ferguson-Smith MA, O'Brien PC, Marshall Graves JA. (2006). Construction of a highly enriched marsupial Y chromosome-specific BAC sub-library using isolated Y chromosomes. Chromosome Research 14(6):657-664. IF: 3.0

31. Gruetzner F, Ashley T, Rowell DM, Marshall Graves JA. (2006). How did the platypus get its sex chromosome chain? A comparison of meiotic multiples and sex chromosomes in plants and animals. Chromosoma. 115(2):75-88.
IF: 3.3

30. Ezaz T, Valenzuela N, Grützner F, Miura I, Georges A, Burke RL, Marshall Graves JA. (2006). An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines: Chelidae) with genetic sex determination. Chromosome Res. 14(2):139-150. IF: 3.0

29. Delbridge ML, Wallis MC, Kirby PJ, Alsop AE, Grützner F, Graves JA. (2006). Assignment of SOX1 to platypus chromosome 20q by fluorescence in situhybridization. Cytogenet Genome Res. 112(3-4):342. IF: 2.0

28. Yue Y, Tsend-Ayush E, Grützner F, Grossmann B, Haaf T. (2006). Segmental duplication associated with evolutionary instability of human chromosome 3p25.1 Cytogenet Genome Res. 112(3-4):202-207. IF: 2.0

27. Tsend-Ayush E, O'Sullivan LA, Grützner FS, Onnebo SM, Lewis RS, Delbridge ML, Marshall Graves JA, Ward AC. (2005). RBMX gene is essential for brain development in zebrafish. Dev Dyn. 234(3):682-688. IF: 3.3

26. Yue Y, Grossmann B, Tsend-Ayush E, Grützner F, Ferguson-Smith MA, Yang F, Haaf T. (2005). Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. Cytogenet Genome Res. 108(1-3):98-105.  IF: 2.0

25. Grützner, F., Graves, J.A.M. (2004). A Platypus’ eye view of the mammalian genome. Invited review. Current Opinion Genetics &Development. 14(6): 642-649 (cover story). IF: 9.3

24. Rens, W., Grützner, F., O’Brien, P.C.M., Fairclough, H., Graves, J.A.M, Ferguson-Smith, M.A. (2004). Resolution and evolution of the duck-billed platypus karyotype with a X1Y1X2Y2X3Y3X4Y4X5Y5 male sex chromosome constitution. Proceedings of the National Academy of Sciences USA. 101 (46):16257-16261 (Nov 8 Epub ahead of print). IF: 10.2

23. Grützner, F., Rens, W., Tsend-Ayush, E., El-Mogharbel, N., O’Brien, P.C.M., Jones, R.C., Ferguson-Smith, M.A., Graves, J.A.M. (2004). In male platypus a meiotic chain of ten chromosomes shares genes with the bird Z and mammal X chromosomes. Nature 432: 913-917 (letter, N&V). (published online 24 October 2004). IF: 32

22. Tsend-Ayush E., Grützner, F., Yue, Y., Grossmann, B., Hänsel, U., Sudbrak, R., Haaf, T. (2004). Plasticity of human chromosome 3 during primate evolution. Genomics 83(2): 193-202. IF: 3.2

21. Santucciu, C., Grützner, F., de Carvalho-Silva D.R., Marshall Graves J.A. (2003). Isolation of chromosomal regions controlling intersex development in a marsupial. Cytogenetics & Genome Research 101(3-4): 224-228. IF: 0.5

20. Grützner, F., Deakin, J., Rens, W., El-Mogharbel, N., Marshall Graves, J.A. (2003). The monotreme genome: a patchwork of reptile, mammal and unique features? Comparative Biochemistry & Physiology A Mol Integr Physiol. 136(4):867-881. IF: 1.5

19. Chapman, M.A., Charchar, F.J., Kingston, S., Bird, C.P., Grafham, D., Rogers, J., Grützner, F., Graves, J.A.M., Green, A.R., Goettgens B. (2003). Comparative and Functional Analysis pf LYL1 Loci Establish Marsupial Sequences as a Model for Phylogenetic Footprinting. Genomics. 81(3): 249-259. IF: 3.4

18. Smith, S.F., Snell, P., Grützner, F., Bench, A.J., Haaf, T., Metcalfe, J.A., Green, A.R., Elgar, G. (2002). Analyses of the extent of shared synteny and conserved gene orders between the genome of Fugu rubripes and human 20q. Genome Research. 12(5): 776-84. IF: 10.1

17. Grützner. F., Crollius, H.R., Lutjens, G., Jaillon, O., Weissenbach, J., Ropers, H.H., Haaf, T. (2002). Four-hundred million years of conserved synteny of human Xp and Xq genes on three Tetraodon chromosomes. Genome Research. 12(9): 1316-1322. IF: 9.8

16. Zimdahl, H., Gosele, C., Lutjens, G., Grützner, F., Kreitler, T., Voss, K., Wanker, E., Knoblauch, M. (2001). Assignment(1) of the Huntington (Hdh) gene, the Huntington associated protein (Hap1) gene, and the Huntington interacting protein (Hip1) gene to rat chromosomes 14, 10, and 12 by radiation hybrid mapping and fluorescent in situ hybridization. Cytogenetics & Cell Genetics. 94(1-2): 101-104.

15. Toder, R., Grützner, F., Haaf, T., Bausch, E. (2001). Species-specific evolution of repeated DNA sequences in great apes. Chromosome Research. 9(6): 431-435.

14. Grützner, F., Zend-Ajusch, E., Stout, K., Munsche, S., Niveleau, A., Nanda, I., Schmid, M., Haaf, T. (2001). Chicken microchromosomes are hypermethylated and can be identified by specific painting probes. Cytogenetics & Cell Genetics. 93(3-4): 265-269.

13. Bouchireb, N., Grützner, F., Haaf, T., Stephens, R.J., Elgar, G., Green, A.J., Clark, M.S. (2001). Comparative mapping of the human 9q34 region in Fugu rubripes. Cytogenetics & Cell Genetics. 94 (3–4).

12. Cai, L., Lindpaintner, K., Browne, J., Grützner, F., Haaf ,T., James M.R., Bihoreau, M. (2000). An anchored YAC-STS framework for the rat genome. Cytogenetics & Cell Genetics. 89(3-4): 168-170.

11. Nanda, I., Zend-Ajusch, E., Shan, Z., Grützner, F., Schartl, M., Burt, D.W., Koehler, M., Fowler, V.M., Goodwin, G., Schneider, W.J., Mizuno, S., Dechant, G., Haaf, T., Schmid, M. (2000). Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: a comparative (re)view on avian sex determination. Cytogenetics & Cell Genetics. 89(1-2):67-78.

10. Brunner, B., Grützner, F., Yaspo, M.-L., Ropers, H.-H., Haaf, T., Kalscheuer, V. (2000). Molecular cloning and chracterisation of the Fugu rubripes MEST/COPG2 imprinting cluster and chromosomal localization in Fugu and Tetraodon nigroviridis. Chromosome Research. 8: 465-476.

9. Gosele, C., Grützner, F., Pesquero, J.B., Silva, J.A. Jr., Junge, T., Ganten, D., Bader, M., Knoblauch M. (2000). Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping. Cytogenetics & Cell Genetics. 89(1-2): 51-52.

8. Grützner, F., Himmelbauer, H., Paulsen, M., Ferguson-Smith, M.A., Ropers, H.-H., Haaf, T. (1999). Comparative Mapping of Mouse and Rat Chromosomes by Fluorescence in situ Hybridization. Genomics. 55: 306-313.

7. Grützner, F., Lütjens, G., Rovira, C., Barnes, D.W., Ropers, H.-H., Haaf, T. (1999). Classical and molecular cytogenetics of the pufferfish Tetraodon nigroviridis. Chromosome Research. 7(8): 655-662.

6. Nanda, I., Shan, Z., Schartl, M., Burt, D.W., Koehler, M., Nothwang, H., Grützner, F., Paton, I.R., Windsor, D., Dunn, I., Engel, W., Staeheli, P., Mizuno, S., Haaf, T., Schmid, M. (1999). 300 million years of conserved synteny between chicken Z and human chromosome 9. Nature Genetics. 21(3): 258-259.

5. Römer I., Grützner F., Winking H., Haaf T., Orth A., Skidmore L., Antczak D., Fundele R. (1999). Genome methylation in eutherian hybrids. Nature. 401: 131-132.

4. Sharon, D., Glusman, G., Pilpel, Y., Khen, M., Grützner, F., Haaf, T., Lancet, D. (1999). Primate Evolution of an Olfactory Receptor Cluster: Diversification by Gene Conversion and Recent Emergence of Pseudogenes. Genomics. 61: 24-36.

3. Gläser, B.*, Grützner, F.*, Willmann, U.*, Stanyon, R., Arnold, N., Taylor, K., Rietschel, W., Zeitler, S., Toder, R., Schempp, W (1998). Simian Y chromosomes: species-specific rearrangements of DAZ, RBM, and TSPY versus contiguity of PAR and SRY. Mammalian Genome. 9(3): 226-31. (*equal contribution)

2. Gläser B., Grützner F., Taylor K., Schiebel K., Meroni G., Tsioupra K., Pasantes J., Rietschel W., Toder R., Willmann U., Zeitler S., Yen P., Ballabio A., Rappold G., Schempp W. (1997). Comparative mapping of Xp22 genes in hominoids-evolutionary linear instability of their Y homologues. Chromosome Research 5(3):167-76.

1. Schempp W., Toder R., Rietschel W., Grützner F., Mayerova A., Gauckler A. (1993) Inverted and satellited Y chromosome in the orangutan (Pongo pygmaeus). Chromosome Research 1(1):69-75.

Book chapter:
Grützner F, Rens W, Watson JM, Ferguson-Smith MA, Graves JAM. The chromosomes of monotreme mammals. New edition of a Chromosome Atlas, published in 2006.

Other publication:
Temple-Smith, P.D., Graves, J.A.M., Grützner, F., Deakin, J., Renfree, M.B., Belov, K., Miller, R., Lindblad-Toh, K., Lander, E.S., Wilson, R.K. (2004). A proposal to sequence the genome of the platypus Ornithorhynchus anatinus. http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/PlatypusSEQ.pdf