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Magnesium in the Central Nervous System

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Magnesium in the Central Nervous System

edited by Robert Vink and Mihai Nechifor

$88.00 | 2011 | Paperback | 978-0-9870730-6-8 | 356 pp

FREE | 2011 | Ebook (PDF) | 978-0-9870730-5-1 | 356 pp

DOI: http://dx.doi.org/10.1017/UPO9780987073051

  • Chapter Details

    Preface
    Robert Vink and Mihai Nechifor
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.001

    SECTION 1 — MAGNESIUM IN NORMAL BRAIN

    Chapter 1 — Free magnesium concentration in human brain
    Stefano Lotti and Emil Malucelli
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.002

    Chapter 2 — Intracellular magnesium homeostasis
    Andrea M.P. Romani
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.003

    Chapter 3 — Magnesium transport across the blood-brain barriers
    Mounir N. Ghabriel and Robert Vink
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.004

    Chapter 4 — Intracellular free Mg2+ and MgATP2− in coordinate control of protein synthesis and cell proliferation
    Harry Rubin
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.005

    Chapter 5 — Magnesium and the Yin-Yang interplay in apoptosis
    Valentina Trapani, Lucia Mastrototaro and Federica I. Wolf
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.006

    Chapter 6 — Brain magnesium homeostasis as a target for reducing cognitive ageing
    Jean-Marie Billard
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.007

    SECTION 2 — MAGNESIUM IN NEUROLOGICAL DISEASES

    Chapter 7 — The role of magnesium therapy in learning and memory
    Michael R. Hoane
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.008

    Chapter 8 — The role of magnesium in headache and migraine
    Lisa A. Yablon and Alexander Mauskop
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.009

    Chapter 9 — Magnesium in edema and blood-brain barrier disruption
    Mehmet Kaya and Bulent Ahishali
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.010

    Chapter 10 — Magnesium and hearing loss
    Isabelle Sendowski, Xavier Holy, Florent Raffin and Yves Cazals
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.011

    Chapter 11 — The role of magnesium in pain
    Hyo-Seok Na, Jung-Hee Ryu and Sang-Hwan Do
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.012

    Chapter 12 — The role of magnesium in traumatic CNS injury
    Naomi L. Cook, Frances Corrigan and Corinna van den Heuvel
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.013

    Chapter 13 — The use of magnesium in experimental cerebral ischaemia
    Bruno P. Meloni, Kym Campbell and Neville W. Knuckey
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.014

    Chapter 14 — Magnesium in subarachnoid hemorrhage
    Walter M. van den Bergh
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.015

    Chapter 15 — Magnesium in clinical stroke
    Jeffrey L. Saver and Sidney Starkman
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.016

    Chapter 16 — Magnesium in cancer: more questions than answers
    Marzia Leidi, Federica I. Wolf and Jeanette A.M. Maier
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.017

    Chapter 17 — Magnesium in Parkinson's disease: an update in clinical and basic aspects
    Kiyomitsu Oyanagi and Tomoyo Hashimoto
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.018

    SECTION 3 — INVOLVEMENT OF MAGNESIUM IN PSYCHIATRIC DISEASES

    Chapter 18 — Magnesium and Alzheimer's disease
    Dehua Chui et al.
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.019

    Chapter 19 — Magnesium and stress
    Magdalena D. Cuciureanu and Robert Vink
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.020

    Chapter 20 — Magnesium in neuroses
    Victoria Papadopol and Mihai Nechifor
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.021

    Chapter 21 — Magnesium, hyperactivity and autism in children
    Marianne Mousain-Bosc, Christian Siatka and Jean-Pierre Bali
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.022

    Chapter 22 — Magnesium in psychoses (schizophrenia, bipolar disorder)
    Mihai Nechifor
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.023

    Chapter 23 — Magnesium and major depression
    George A. III Eby, Karen L. Eby and Harald Murck
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.024

    Chapter 24 — Magnesium in drug abuse and addiction
    Mihai Nechifor
    DOI: http://dx.doi.org/10.1017/UPO9780987073051.025

Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level.

The exact role and regulation of magnesium in particular remains elusive, largely becaue inracelluar levls are so difficult to routinely quantify. Nonetheless, the importance of magesium o normal central nervous system actvit is self-evident given the complicated omeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism.

There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration.

This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium’s involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behaviour.

It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesium’s role in biological systems that has inspired the collation of this volume of work.

 

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