Menopause Research

Research Leaders: Professor Alastair MacLennan

The Menopause Research group is a multidisciplinary group based in the Discipline of Obstetrics and Gynaecology at the Women's & Children's Hospital. It conducts epidemiological studies, large clinical trials and educational programs on the menopause and postmenopausal women's health.

The group played a major educational role in 2009 by supporting frequent clinical and scientific evening meetings with the Adelaide Women's Health Group.

The group also contributed to the results of LIBERATE, a randomised placebo control trial of tibolone after breast cancer. The group's epidemiological research continues using the South Australian Health Omnibus Survey and currently the group is participating in a multicentre clinical trial of a new hormonal contraceptive skin patch, which will continue until 2011.

Research Priorities:

• Epidemiological studies on pelvic floor dysfunction, alternative therapies and hormone therapy use, quality of life in collaboration with the Department of Health. Population Research and Outcome Studies Unit using the SA Health Omnibus Survey.
• Cochrane collaboration systematic review on HRT and vasomotor symptoms.
• The Women's International Study of Long Duration Oestrogen after Menopause (WISDOM).
• Research into Memory, Brain function and Oestrogen Replacement (REMEMBER study) and genetic sub study.
• Tibolone after breast cancer four-year study (LIBERATE)
• Long-term Intervention on Fractures with Tibolone Trial (LIFT).
• Phase I, II and III studies on new treatments for menopause and osteoporosis.