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General Enquiries:

Director:
Assoc. Prof. Simon A. Koblar

Email: simon.koblar@adelaide.edu.au

University of Adelaide,
School of Medicine,
c/o Medical School South Bld (Room S511a)
Frome Rd
Adelaide SA 5005
AUSTRALIA

Clinical Academic Neurologist, Dept. Neurology,
The Queen Elizabeth Hospital,
Woodville SA 5011

Clinical Advisor,
Centre for Stem Cell Research,
Robinson Institute,
University of Adelaide

Tel:  +61 8 8222 6125

Fax: +61 8 8222 6042

Publication Highlights (2005 - 2012)

2012:

Cheng YC, et al., including Koblar SA, Lewis M, on behalf of the International Stroke Genetics Consortium: Are myocardial infarction-associated single nucleotide polymorphisms associated with ischaemic stroke? Stroke 2012;43(4):980-986; Epub 2012 Feb 23, PMID:22363065.

Lees JS, Sena ES, Egan KJ, Antonic A, Koblar SA, Howells DW, Macleod MR.  Stem cell-based therapy for experimental stroke: a systematic review and metanalysis. Int J Stroke 2012 (in press).

Leong WK, Henshall TL, Arthur A, Kremer KL, Lewis MD, Helps SC, Field J, Hamilton-Bruce MA, Warming S, Manavis J, Vink R, Gronthos S, Koblar SA.  Human Adult Dental Pulp Stem Cells Enhance Post-Stroke Functional Recovery through Non-Neural Replacement Mechanisms. Stem Cells Translational Medicine 2012; Mar;1(3):177-187.

Moey AW, Koblar SA, Chryssidis S, Robinson M, Jannes J.  Endovascular therapy after stroke in a patient treated with dabigatran. Med J Aust. 2012; Apr 16; 196(7):469-71, PMID:22509880.

Tran HB, Lewis MD, Tan LW, Lester SE, Baker LM, Ng J, Hamilton-Bruce MA, Hill CL, Koblar SA, Rischmueller M, Ruffin R, Wormald P-J, Zalewski PD, Lang CJ.  Immunolocalization of NLRP3 Inflammasome in Normal Murine Airway Epithelium and Changes following Induction of Ovalbumin-Induced Airway Inflammation. Journal of Allergy 2012:819176. Epub 2012; Mar 18. PMID:22523501.

2011:

Arthur A, Zannettino A, Panagopoulos R, Koblar SA, Sims NA, Stylianou C, Matsuo K, Gronthos S. EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation. Bone 2011;48(3):533-542, Epub 2010 Nov 5. PMID:21056708.

Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox K, Hennerici MG, Mattle HP, Rothwell PM, Cordove A, Fratacci MD and PERFORM study investigators including Jannes, J. Terutroban versus Aspirin with cerebral ischemic events: a randomized, double-blind, parallel-group trial. Lancet 2011;377(9782): 2013-2022.

Cheng JN, Jannes J, Lee A, Heddle R, Koblar SA. A Patient with Anaphylaxis after Alteplase Infusion. J Clin Neurosci (2011) 19(2); 314-315. Epub Nov 17 2011, PMID:22099072.

Golledge J, Clancy P, Maguire J, Lincz L, Koblar SA. The role of Tenacin C in cardiovascular disease. Cardiovascular Research 2011;92(1):19-28, PMID:21712412.

Kleinig T, Leyden JM, Lee A, Jannes J.  A Population-based study of thrombolysis for acute stroke in South Australia. Medical Journal of Australia 2011;194(3):111-115.

Leung ES, Hamilton-Bruce MA, Koblar SA.  Transient ischaemic attacks assessment and management. Australian Family Physician, 2011 Jan-Feb;40(1-2):9; author reply 9.

Leung E, Hamilton-Bruce MA, Stocks N, Koblar SA.  10 minute consultation ‘Funny Turn'. British Medical Journal. British Medical Journal 2011;343 doi: 10.1136/bmj.d7465 (Published 5 Dec. 2011) PMID:22144408.

Leyden JM, Chong WK, Kleinig T, Lee A, Field JB, Jannes J.  A Population-based study of thrombolysis for acute stroke in South Australia. Medical Journal of Australia 2011; 194(3): 111-115.

McLennan S, Lam A, Mathias J, Koblar SA, Hamilton-Bruce M, Jannes J.  Role of vasodilation in cognitive impairment. Int J Stroke 2011 6(3):280, PMID:21557820.

Milton AG, Aykanat VM, Hamilton-Bruce MA, Nezic M, Jannes J, Koblar SA.  Association of Phosphodiesterase 4D (PDE4D) Gene and Cardioembolic Stroke in an Australian Cohort. Int J Stroke 2011 6(6) 420-6, PMID:21989204.

Phillips MC, Leyden JM, Chong WK, Kleinig T, Czapran P, Lee A, Koblar SA, Jannes J.  Young Ischemic Stroke in South Australia: More Obesity, Marijuana and Amphetamine Abuse. Med J Australia 2011, 195(10); 610-614. PMID:22107013. 

2010:

Chen CS, Rudkin AK, Lee AW, Lam A, Patel S, Khoo E-W, Hamilton-Bruce MA, Jannes J, Koblar SA. Association of Retinal Nerve Fibre Layer and Brain Volume Changes in Leukoaraiosis. 18th International Neuro-Opthalmology Society Programme, Lyon, France. 2010; X-P 3.

Leung ES, Hamilton-Bruce MA, Koblar SA. Transient ischaemic attacks assessment and management. Australian Family Physician 2010 Nov; 39(11):820-824.

Manning JA, Lewis M, Koblar SA, Kumar S. An essential function for the centrosomal protein NEDD1 in zebrafish development. Cell Death Differ. 2010 Aug;17(8):1302-14. Epub 2010 Feb 12, PMID:20150915.

Roberts RR, Ellis M, Gwynne R, Bergner AJ, Lewis M, Beckett EA, Bornstein JC, Young HM.  The first intestinal motility patterns in fetal mice are not mediated by neurons or interstitial cells of Cajal.  J Physiol. 2010 Apr 1;588(Pt 7):1153-69. Epub 2010 Feb 8, PubMed PMID: 20142273.

Rosser A, Phillips M, Hamilton-Bruce M, Jannes J, Chryssidis S, Sebben R, Koblar SA. Case Report: Use of the Penumbra System (PS) in two Octogenarians. Poster Abstracts. Int J Stroke 2010; 5(Suppl 1): 2.

2009:

Arthur A, Stylianou C, Koblar S, Matsuo K, Gronthos S.  EphB/ephrin-B interactions assist in MSC niche maintenance and contribute to bone remodelling following injury. Bone Journal Australia 2009;44 Suppl. 1:S142-S143.

Arthur A, Shi S, Zannettino AC, Fujii N, Gronthos S*, Koblar SA*.  Implanted Adult Human Dental Pulp Stem Cells induce endogenous axon guidance. Stem Cells 2009;27(9):2229-37. *Co-senior authorship

Arthur A, Koblar SA, Shi S, Gronthos S.  Eph/ephrinB mediated mobilization of Dental Pulp Stem Cell in tooth repair. Journal of Dental Research 2009;88(9):829-34.

Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox K, Hennerici MG, Mattle HP, Rothwell PM, Jannes J et al.  Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) study. Cerebrovasc Dis. 2009;27(5):509-18.

Price CJ, Blacker DJ, Grimley RS, Dewey HM, Gerraty RP, Koblar SA, Denisenko SM, Storey CE, Bladin CF, Hill KM.  National survey of management of transient ischaemic attack in Australia: Take Immediate Action. Medical J Australia 2009;191(1): 17-20.

2008:

Lam A, Hamilton-Bruce MA, Jannes J, Koblar SA.  Cerebral small vessel disease; genetic risk assessment for prevention and treatment. Molecular Diagnosis and Therapy 2008;12(3):145-156.

Leung E, Koblar SA, Hamilton-Bruce MA, Price C.  TIA Assessment. Australian Family Physician 2008;37(3):103.

Milton AG, Hamilton-Bruce MA, Koblar SA, Jannes J.  The ClC- KbT481S Chloride Channel Gene Polymorphism, Ischaemic Stroke and Hypertension. The Open Neuroscience Journal 2008;2:6-8.

2007:

Vidovic M, Nighorn A, Koblar SA, Maleszka R.  Eph receptor and ephrin signalling in developing and adult brain of the honeybee (Apis mellifera). Developmental Neurobiology 2007;67:233-251.

Stokowski A, Shi S, Barthold M, Gronthos S*, Koblar SA*.  EphB/ephrin-B interaction mediates adult stem cell attachment, spreading, and migration: Implications for dental tissue repair. Stem Cells 2007;25 (1):156-164. *Co-senior authorship

Hamilton-Bruce A, Hudson N, Smith H.  Epilepsy Artwork Collaboration. Association of Neurophysiology Technologists of Australia (ANTA) Journal 2007;11-12.

Barry C, Koblar SA, O'Carroll D.  Frontier Technologies for Brain Repair. Australasian Science 2007;28 (7):16-18. (Feature article with Front cover illustration)

2006:

Milton AG, Jannes J, Hamilton-Bruce MA, Koblar SA.  Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension 2006;47(3):e12.

Jannes J, Hamilton-Bruce MA, Koblar SA.  Response: Tissue Plasminogen Activator -7351C/T Polymorphism and Lacunar Stroke. [Letter] Stroke 2006;37(2):329-330.

Koblar S.  Stem cell treatment - hype or hope? Stroke Society of Australasia Annual Scientific Meeting Handbook 2006;49.

Armstrong CA, Bevan SN, Gormley KT, Markus HS, Koblar SA.  Tissue Plasminogen Activator -7351C/T Polymorphism and Lacunar Stroke. [Letter] Stroke 2006;37(2):329.

2005:

Short CL, Scott G, Blumbergs PC, Koblar SA.  A case of presumptive primary lateral sclerosis with upper and lower motor neurone pathology. J Clin Neurosci. 2005;12(6):706-9.

Jannes J, Milton AG, Hamilton-Bruce MA, Koblar SA.  Chloride Channel Gene Polymorphism and Stroke. Journal of the Neurological Sciences 2005;Nov: S154.

Jayasena CS, Flood WD, Koblar SA.  High EphA3 expressing ophthalmic trigeminal sensory axons are sensitive to ephrin-A5-Fc: Implications for lobe specific axon guidance. Neuroscience 2005;135(1):97-109.

Jannes J, Hamilton-Bruce A, Koblar S.  Lacunar Stroke: Genetic Risk assessment for Prevention and Treatment. BIO 2005 International Convention Program 2005;June: 22-23.

Hamilton-Bruce MA, Tsui A, Donk MB, Dowling KJ, Jones JA, Lee A, Purdie GH.  Nerve Conduction Tests (NCTs): Inter-Equipment and Intra-Examiner Assessment. Journal of the Neurological Sciences 2005;Nov: S461.

Lee AW, Nikitins I, Pozza C, Koblar SA.  Pleural mesothelioma with extension into the thoracic spinal cord. Intern Med J. 2005;35(3):195-6.

Hamilton-Bruce MA.  The Queen Elizabeth Hospital & Health Service (TQEH&HS): Neurophysiology Plus Workshop Report. Association of Neurophysiological Technologists of Australia (ANTA) Journal, 2005;Aug: 10-12.

 

Media Appearances

  • SA Koblar - Channel 10 TV's Projects: ‘Locked-in Syndrome, Stroke and stem cells' 8th March 2012
  • SA Koblar - ‘Stem Cell Tourism' at the Royal Institute, Adelaide, Nov 2011; also broadcast on ABC Radio National's Science Show
  • SA Koblar - 5AA radio - ‘Stem Cells and Stroke' for National Stroke Week, Sept 2011
  • SA Koblar - ‘Don't Speak', an event to raise funds for the Peter Couche Foundation (for Stroke research), held during National Stroke Week, Sept 2011
  • SA Koblar - two public lectures for National Stroke Week, Sept 2010
  • SA Koblar - Channel 10 News, National Stroke Week, Sept 2010
  • J Jannes - public lecture for National Stroke Week, Sept 2010
  • MA Hamilton-Bruce and AG Milton - Radio 5EFM Community Radio, 'Stroke', May 2010.
  • SA Koblar - public lecture for National Stroke Week, Sept 2009
  • J Jannes, S Koblar, M Phillips, L Dodd, MA Hamilton-Bruce - a Stroke of Luck, Adelaide Advertiser article, page 15, review section, May 2009
  • J Jannes, S Koblar, M Phillips, L Dodd - Health Funds: Keeping Private Cover is Cheaper, Adelaide Advertiser article, page 33-34, Making Money section, May 2009
  • SA Koblar - Channel 10 News, 19 Sept 2007
  • J Jannes and MA Hamilton-Bruce - Channel Seven News - Genes play a vital role in preventing blood clots in the brain. 4th July 2004 (also aired on National Seven Network Sunrise on 5th July, relayed to regional stations nationwide)

Team members have continued to present at community meetings to raise awareness about our research as well as funding needs, to support research.