MICRO 2506 - Medical Microbiology and Immunology II

North Terrace Campus - Semester 1 - 2019

This course is an introduction to basic immunology, virology and microbiology for MBBS Level 2 students. Emphasis is first placed on understanding the fundamentals of these disciplines, with examples relevant to clinical and diagnostic medicine. Topics covered in Immunology include: Innate immunity; specific humoral effector mechanisms; cells and tissues of the immune system; antigen recognition by T cells; cell-mediated immunity, hypersensitivity; human leukocyte antigen (HLA) polymorphism, transplantation; autoimmunity; immunodeficiency. Virology include: virus classification, structure and replication; pathogenesis, epidemiology and control of virus infections; respirator, gastrointestinal and sexually transmitted viruses; virus diagnostic methods. Microbiology include: bacterial structure, classification and growth; mechanisms of gene transfer; diagnostic microbiology; mechanisms of bacterial pathogenesis; sterilisation and disinfection; meningitis and encephalitis; antibiotics and resistance; medical mycology and parasitology

  • General Course Information
    Course Details
    Course Code MICRO 2506
    Course Medical Microbiology and Immunology II
    Coordinating Unit School of Biological Sciences
    Term Semester 1
    Level Undergraduate
    Location/s North Terrace Campus
    Units 3
    Contact Up to 3.5 hours per week
    Available for Study Abroad and Exchange N
    Prerequisites MBBS Level I
    Incompatible MICRO 3003
    Assumed Knowledge BIOLOGY 1101 & BIOLOGY 1201
    Restrictions Available to Level II MBBS students only
    Course Description This course is an introduction to basic immunology, virology and microbiology for MBBS Level 2 students. Emphasis is first placed on understanding the fundamentals of these disciplines, with examples relevant to clinical and diagnostic medicine. Topics covered in Immunology include: Innate immunity; specific humoral effector mechanisms; cells and tissues of the immune system; antigen recognition by T cells; cell-mediated immunity, hypersensitivity; human leukocyte antigen (HLA) polymorphism, transplantation; autoimmunity; immunodeficiency.
    Virology include: virus classification, structure and replication; pathogenesis, epidemiology and control of virus infections; respirator, gastrointestinal and sexually transmitted viruses; virus diagnostic methods.
    Microbiology include: bacterial structure, classification and growth; mechanisms of gene transfer; diagnostic microbiology; mechanisms of bacterial pathogenesis; sterilisation and disinfection; meningitis and encephalitis; antibiotics and resistance; medical mycology and parasitology
    Course Staff

    Course Coordinator: Dr Christopher Wong

    Course Timetable

    The full timetable of all activities for this course can be accessed from Course Planner.

  • Learning Outcomes
    Course Learning Outcomes
    1 To introduce and describe the classification, structure, classification and physiology of bacteria that infect humans. To understand the importance of pathogenic bacteria in human disease with respect to infections of the respiratory tract, gastrointestinal tract, urinary tract, skin and soft tissue.
    2 To learn about the diseases caused by anaerobic bacteria. To introduce basic and molecular techniques employed in diagnostic bacteriology laboratories. To learn about the use of antibiotics and resistant mechanisms encoded in bacteria to neutralise these chemical agents.
    3 To show how bacterial-related meningitis, encephalitis and sexually-transmitted diseases are diagnosed, treated and managed. To introduce basic concepts in medical mycology. To introduce bacteria that causes sexually transmitted diseases
    4 To learn about non-specific defences provided by the innate immune system, To introduce the cells and tissues of the immune system. To learn about the humoral arm of the adaptive immune response. To learn about the cell-mediated arm of the adaptive immune response.
    5 To understand how B and T cells develop . To understand the concept and function of immunological tolerance. To discuss human leukocyte antigen polymorphism in the context of transplantation and autoimmunity.
    6 To discuss the mechanisms underlying immunological hypersensitivity reactions
    7 To introduce and describe the classification and structure of medically important viruses that infect humans. To understand how virus structure impacts on transmission of viruses by respiratory, faecal-oral, blood-borne and sexual transmission routes.
    8 To understand the life cycles of medically important viruses including: poliovirus; hepatitis C virus; influenza A virus; human immunodeficiency virus; hepatitis B virus; herpes simplex virus; varicella zoster virus; gastroenteritis viruses and human papilloma viruses. To describe the factors that contribute to the pathogenesis of medically important viruses. To understand why some viruses cause transient and others cause persistent virus infections. To introduce principles behind the epidemiology and control of virus infections.
    9 To understand the clinical relevance of treatments for virus infections including: hepatitis B virus, hepatitis C virus, human immunodeficiency virus, respiratory viruses, human papillomaviruses and gastroenteritis viruses. To introduce basic and molecular techniques employed in diagnostic virology laboratories
    University Graduate Attributes

    This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

    University Graduate Attribute Course Learning Outcome(s)
    Deep discipline knowledge
    • informed and infused by cutting edge research, scaffolded throughout their program of studies
    • acquired from personal interaction with research active educators, from year 1
    • accredited or validated against national or international standards (for relevant programs)
    1-10
  • Learning Resources
    Recommended Resources
    Review of Medical Microbiology and Immunology
    by Warren Levinson, 2008, 10th edition
    McGraw Hill Lange
     

    Basic Immunology: Functions and Disorders of the Immune System
    Abbas & Litchman
    3rd Edition - Updated Edition
  • Learning & Teaching Activities
    Learning & Teaching Modes
    Lectures
    An average of three lectures per week which are recorded for MyUni

    Tutorials
    An average of one tutorial per week
    Workload

    The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

    The information below is provided as a guide to assist students in engaging appropriately with the course requirements.A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required.

    This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
    Learning Activities Summary
    No lecture
    Week Lecture Topic Lecturer
    Week 1 Revision of the Structure,
    Classification and Physiology of bacteria (Chps 1-13)
    Dr. Connor Thomas
    Acute Bacterial Infections of the Resp Tract (Chp 19) Dr. Celia Cooper
    Bacterial Enteric Infections and Food Poisoning (Chp 18) Dr. Celia Cooper
    Week 2 Adelaide Cup Holiday
    Diseases Caused by Anaerobic Bacteria (Chp 14) Dr. Ivan Bastian
    Acute Bacterial Infections of the Urinary Tract Dr. Gerhard Weldhagen
    Week 3 Skin and Soft Tissue Infections (Chp 15) Prof. John Turnidge
    Medical Mycology (Chp 47-50) Dr. Sarah Kidd
    Sexually Transmitted Disease (Bacterial) Dr. Stephen Kidd
    Week 4 Acute Non-Viral Infections of the CNS Prof. John Turnidge
    No lecture
    No lecture
    Week 5 No lecture
    No lecture
    Theory Test 1 (Refer to Myuni for seating allocations)
    Week 6 Innate Immunity (Chp 8,57,63) Dr. Chris Wong
    Cells & Tissues of the Immune System (Chp 58) Prof. Shaun McColl
    Specific Humoral Effector Mechanisms I (Chp 59) Dr. Chris Wong
    MID SEMESTER BREAK
    Week 7 Specific Humoral Effector Mechanisms II (Chp 60) Dr. Chris Wong
    Antigen Presentation (Chp 61) Prof. Toby Coates
    The Roles of T Cells: Help to B cells, CMI and Memory (Chp 61) Prof. Shaun McColl
    Week 8 T Cell Development & Immunological Tolerance (Chp 66) Prof. Shaun McColl
    Transplantation (Chp 62) Prof. Toby Coates
    Hypersensitivity Reactions (Chp 65) Dr. Olivier Fahy
    Week 9 No lecture
    No lecture
    Theory Test 2 (Refer to Myuni for seating allocations)
    Week 10 Pathogenesis of Virus Diseases 1 (Chp 32) Dr. Mohammed Alsharifi
    Pathogenesis of Virus Diseases 2 (Chp 32) Dr. Mohammed Alsharifi
    Virus Infections & Immune Evasion Dr. Karla Helbig
    Week 11 Epidemiology and Control of Virus Infections (Chp 35,36) Dr. Mohammed Alsharifi
    Human Immunodeficiency Virus Infection (Chp 45) Dr. Amanda Aloia
    Hepatitis B and C Virus Infections (Chp 41) A/Prof. Michael Beard
    Week 12 Arbovirus Infections (Chp 42) Dr. Mohammed Alsharifi
    Respiratory Virus Infections (Chp 39) Dr. Mohammed Alsharifi
    Virus Gastroenteritis (Chp 40) Dr. Rodney Ratcliff
    Week 13 Queen's Birthday Holiday
    No lecture
    Theory Test 3 (Refer to Myuni for seating allocations)
  • Assessment

    The University's policy on Assessment for Coursework Programs is based on the following four principles:

    1. Assessment must encourage and reinforce learning.
    2. Assessment must enable robust and fair judgements about student performance.
    3. Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
    4. Assessment must maintain academic standards.

    Assessment Summary
    Assessment Task Task Type Hurdle Weighting Learning Outcome
    Tutorials Formative

    No

    0% e.g. LO2
    Theory
    Tests (3)
    Summative No 30% e.g. 1,2,3,4,6
    End of Semester Exam Summative No 70%
    Assessment Detail

    The assessment methods used for this course are designed to address a number of the MBBS graduate attributes. The indicators provided were reviewed and where appropriate incorporated into the following assessment components, which are:

     

    Tutorials (0%)

    The tutorials are designed as formative assessments to allow students to clarify concepts taught during preceeding lectures. 2 tutorials will be held for each of the 3 blocks of lectures (Microbiology, Immunology and Virology) making a total of 6 tutorials.

     

    Theory Tests (30%)

    These summative assessments (3) will be held at the end of each block of lectures (Microbiology, Immunology and Virology) during nominated lecture time slots. Students will be tested on their knowledge and understanding of the content of each block of lectures. Each test will be a combination of MCQ and/or modified SAQ type questions. The test will be marked and returned to the the students as feedback.

     

    End of semester examination (70%)

    This summative assessment comprehensively tests the learning outcomes of the entire theory component of the course. Students will be tested on their knowledge and understanding of the content taught since the beginning of this course.

    Submission
    Late Submission
    If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that the assignment is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days late or more without an approved extension can only receive a maximum of 50% of the marks available for that assignment.
    Course Grading

    Grades for your performance in this course will be awarded in accordance with the following scheme:

    M10 (Coursework Mark Scheme)
    Grade Mark Description
    FNS   Fail No Submission
    F 1-49 Fail
    P 50-64 Pass
    C 65-74 Credit
    D 75-84 Distinction
    HD 85-100 High Distinction
    CN   Continuing
    NFE   No Formal Examination
    RP   Result Pending

    Further details of the grades/results can be obtained from Examinations.

    Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

    Final results for this course will be made available through Access Adelaide.

  • Student Feedback

    The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

    SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.

  • Student Support
  • Policies & Guidelines
  • Fraud Awareness

    Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student’s disciplinary procedures.

The University of Adelaide is committed to regular reviews of the courses and programs it offers to students. The University of Adelaide therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.