Professor Robert McLaughlin

Professor Robert McLaughlin
 Position Chair of Biophotonics
 Org Unit Adelaide Medical School
 Email robert.mclaughlin@adelaide.edu.au
 Telephone +61 8 8313 9942
 Location Floor/Room 3 17 ,  The Braggs ,   North Terrace
  • Biography/ Background

    I am head of the Bioengineering Imaging Group at The University Adelaide, and am also Managing Director of the medical device start-up company, Miniprobes. I currently lead a research team developing highly miniaturised imaging probes, small enough to be encased within hypodermic needles. My team of engineers, physicists and computer scientists is based in the Centre for Nanoscale Biophotonics and is part of the Institute for Photonics and Advanced Sensing.

    After three years as a researcher at the University of Oxford, I spent five years in the medical imaging industry, including as a Product Manager with Siemens Medical Solutions. I was responsible for the development of three medical devices, two with FDA regulatory approval.

    Returning to academia in 2007, I have focused on the development of optical imaging technologies, particularly optical coherence tomography and fluorescence. I have been awarded over $5M in research grants. With 12 years of research experience, I have a Google Scholar h-index of 27. I have co-authored 2 book chapters, 7 patents and 66 journal papers. I received the 2014 WA Innovator of the Year Award, and the 2015 Australian Innovation Challenge. In 2016, I was awarded the prestigious South Australian Premier’s Research and Industry Fund Research Fellowship.

    In 2014, I was appointed as a Councilor of the Australian Optical Society. In 2016, I was appointed Chair of Biophotonics at the University of Adelaide.

  • Awards & Achievements

    2015: The Australian Innovation Challenge: Overall winner and Health Category winner.

    2014: Western Australian Innovator of the Year, WA Department of Commerce.

    2014:  UWA Vice-Chancellor’s Mid-career Research Award.

    2014: UWA Vice-Chancellor’s Award for Impact and Innovation.

    2014: 1st prize, SPIE Start-up Challenge, San Francisco, CA, USA.

    2013: Finalist, Australian Museum Eureka Prizes: “Innovative Use of Technology”.

    2012: Finalist, Australian Museum Eureka Prizes: “Innovative Use of Technology”.

    2012: Finalist, Centenary Institute Lawrence Creative Prize

    2011: National Breast Cancer Foundation Patron’s Award: “Innovation and Vision in Research”

  • Research Funding

    $1,000,000      2016-2019 South Australian Premier’s Research and Industry Fund Fellowship (McLaughlin) 

    $482,200         2016-2018 ARC Discovery Grant (DP160104175)

    “Visualising vascular adaptation at the micro-scale in humans” (Green, McLaughlin)

    $45,000           2016 Photonics Catalyst Program, South Australian Govt.

    “Image-guided surgery for safer and faster glaucoma treatment” (McLaughlin, Casson, Previn)

    $47,500           UWA NHMRC Equipment Grant, “Philips Premium Portable CX50 Ultrasound System” (Noble, Pillow, Gill, Laing, Nowak, McLaughlin, Kennedy, Hodgetts, Pinniger)

    $355,100         2015-2017 ARC Discovery Grant (DP150104660)

    “Quantitative multi-modal optical imaging of deep tissue – a new window onto disease” (McLaughlin)

    $16,500           UWA Research Collaboration Award 2015-2016 (McLaughlin)

    $5,000             SPIE Education Outreach Grant 2015 (McLaughlin)

    $16,645           2015 Medical and Health Research Infrastructure Fund (MHRIF), Round 18, Dept. Health. (McLaughlin)

    $726,676         2014-2016 Chevron Australia / Fiona Wood Foundation

    “Measuring airway capacity using optical coherence tomography” (McLaughlin, Sampson)

    $64,000           2015 Intuitive Surgical Technology Research Grant (San Francisco, USA),

    “Smart biopsy needles for real-time tissue assessment in lung cancer” (McLaughlin, Sampson)

    $25,000           2015 Breast Cancer Research Centre WA (BCRC_WA 201406),

    “Fluorescent biomarkers for improved breast cancer surgery” (McLaughlin, Fuller)

    $317,111         2014-2016 NHMRC Development Grant (APP1076050),

    “Development of microscope-in-a-needle devices for improved clinical diagnostics” (McLaughlin, Sampson, Noble, Yeoh, Olynyk)

    $50,000           2014 Commercialisation Australia (CAU06334), Department of Industry, Innovation, Science, Research and Tertiary Education (DIISRTE)

    “Business plan for microscope-in-a-needle imaging technology” (McLaughlin, Sampson)

    $13,407           2014 Medical and Health Research Infrastructure Fund (MHRIF), Round 17, Dept. Health. (McLaughlin) 

    $15,000           2013 UWA Research Collaboration Award

    “The next generation microscope-in-a-needle: Fluorescence + optical coherence tomography to find cancer” (McLaughlin, Boudoux)

    $99,537           2013 Cancer Council WA Research Project Grant (ID 1057820),

    “Intra-operative assessment of lymph node metastasis in breast cancer with optical imaging” (McLaughlin, Saunders, Sampson)

    $20,000           2013 UWA Faculty of Engineering, Computing and Mathematics

    Research Development Grants,

    “Optical coherence tomography for quantitative assessment of burn scars” (McLaughlin)

    $98,551           2012 Cancer Council WA Research Project Grant (ID 1052459),

    “Pre-operative assessment of neoadjuvant therapy for breast cancer using optical

    coherence tomography” (McLaughlin, Saunders, Sampson)

    $15,000           2012 Royal Perth Hospital Medical Research Foundation,

    “Early detection of pathological scarring using 3D optical imaging” (McLaughlin, Wood, Kennedy, Sampson)

    $539,685         2012-2014 NHMRC Development Grant (APP1038871)

    “Development of a new surgical-guidance tool for intra-operative tumour margin assessment in breast cancer” (McLaughlin, Saunders, Sampson)

    $200,000         2012 National Breast Cancer Foundation Novel Concept Award,

    “A new tool for intra-operative tumour margin assessment”. (McLaughlin, Saunders, Sampson, Kennedy)

    $300,000         2011-2013 Cancer Council WA Research Fellowship

    “Improved intra-operative breast cancer imaging with OCT” (McLaughlin)

    $25,760           2010 UWA Safety Net Award, (McLaughlin)

    $21,411           2010 Perpetual Ltd., “Better imaging to improve cancer surgery” (McLaughlin, Kennedy, Saunders, Sampson)

    $90,000           2009 Perpetual Ltd., “A new breast cancer imaging probe: combining ultrasound with optical biopsy”. (McLaughlin, Saunders, Sampson)

    $198,640         2008 National Breast Cancer Foundation Novel Concept Award,

    “Steps towards an in vivo optical biopsy: Assessing lymph node metastasis using Optical Coherence Tomography”. (McLaughlin, Saunders, Sampson)

    $22,000           2008 UWA Research Grants Scheme, “Improved Breast Cancer Surgery with Optical Imaging”. (McLaughlin)

    $267,029         2007 Raine Medical Research Foundation, “Bringing Optical Imaging into clinical practice for breast cancer and breathing disorders”. (McLaughlin)

  • Publications

    Book Chapters:

     

    1. R.A. McLaughlin, D. Lorenser, D.D. Sampson, “Needle Probes in Optical Coherence Tomography”, in Handbook of Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring, and Material Science (Ed.: V. V. Tuchin), Springer, New York, 2nd Edition, ISBN: 978-1-4614-5175-4 (Print) 978-1-4614-5176-1 (Online), 2013.
    2. D. Lorenser, R.A. McLaughlin, D.D. Sampson, “Optical coherence tomography in a needle format”, in Optical Coherence Tomography: Technology and applications (Ed.: W. Drexler, J.G. Fujimoto), Springer, New York, 2nd Edition, p2413-2472, ISBN: 978-3319064185, 2015.

     

    Journal Papers:

     

    1. M. Villiger, D. Lorenser, R.A. McLaughlin, B.C. Quirk, R.W. Kirk B.E. Bouma,  D.D. Sampson, “Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour,” Scientific Reports, Scientific Reports 6:28771; doi: 10.1038/srep28771 (2016).
    2. S. Es’haghian, P. Gong, L. Chin, K.-A. Harms, A. Murray, S. Rea, B.F. Kennedy, F.M. Wood, D.D. Sampson, R.A. McLaughlin, “Investigation of optical attenuation imaging using optical coherence tomography for monitoring of scars undergoing fractional laser treatment,” J. Biophotonics, accepted for publication April 2016.
    3. P. Gong, S. Es’haghian, F.M. Wood, D.D. Sampson, R.A. McLaughlin, “Optical coherence tomography angiography for longitudinal monitoring of vascular changes in human cutaneous burns”, Experimental Dermatology, accepted for publication April 2016.
    4. P. Gong, S. Es’haghian, K.-A. Harms, A. Murray, S. Rea, B.F. Kennedy, F.M. Wood, D.D. Sampson, R.A. McLaughlin, “Optical coherence tomography for longitudinal monitoring of vasculature in scars treated with laser fractionation,” J. Biophotonics, 9(6):626-636, 2016, DOI 10.1002/jbio.201500157.
    5. B.F. Kennedy, R.A. McLaughlin, K.M. Kennedy, L. Chin, P. Wijesinghe, A. Curatolo, A. Tien, M. Ronald, B. Latham, C. M. Saunders, D.D. Sampson, “Investigation of optical coherence micro-elastography as a method to visualize cancers in human breast tissue,” Cancer Research, 75(16):3236-3245, 2015.
    6. K.M. Kennedy, L. Chin, R.A. McLaughlin, B. Latham, C.M. Saunders, D.D. Sampson, B.F. Kennedy, “Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography,” Scientific Reports, 5:15538, 2015, doi: 10.1038/srep15538.
    7. L. Scolaro, D. Lorenser, W.-J. Madore, R.W. Kirk, A.S. Kramer, G.C. Yeoh, N. Godbout, D.D. Sampson, C. Boudoux, R.A. McLaughlin, “Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of fluorescently labeled antibodies deep in tissue,” Biomedical Optics Express, 6(5):1767-1781, 2015.
    8. S. Es’haghian, K.M. Kennedy, P. Gong, D.D. Sampson, R.A. McLaughlin, B.F. Kennedy, “Optical palpation in vivo: imaging human skin lesions using mechanical contrast,” J. Biomedical Optics, 20(1):016013, 2015. PMID 25588164
    9. R.W. Kirk, B.F. Kennedy, D.D. Sampson, R.A. McLaughlin, “Near video-rate optical coherence elastography by acceleration with a graphics processing unit,” IEEE/OSA Journal of Lightwave Technology, 33(16):1-5, 2015.
    10. Z. Jahanzad, Y.M. Liew, M. Bilgen, R.A. McLaughlin, C.O. Leong, K.H. Chee, Y.F.A. Aziz, N.M. Ung, K.W. Lai, S.C. Ng, E. Lim, “Regional assessment of LV wall in infarcted heart using tagged MRI and cardiac modelling,” Physics in Medicine and Biology, 60:4015-4031, 2015.
    11. T.K. Ansell, P.K. McFawn, R.A. McLaughlin, D.D. Sampson, P.R. Eastwood, D.R. Hillman, H.W. Mitchell, P.B. Noble, “Does airway smooth muscle length adaptation modify the airway response to a sustained change in transmural pressure?” J. Applied Physiology, 118(5):533-543, 2015. DOI: 10.1152/japplphysiol.00724.2014, PMID: 25729015
    12. Y.M. Liew, R.A. McLaughlin, B.T. Chan, Y.F. Abdul Aziz, K.H. Chee, N.M. Ung, L.K. Tan, K.W. Lai, S. Ng, E. Lim, “Motion corrected LV quantification based on 3D modelling for improved functional assessment in cardiac MRI,” Physics in Medicine and Biology, 60:2715-2733, 2015. PMID: 25768708
    13. P. Wijesinghe, R.A. McLaughlin, D.D. Sampson, B.F. Kennedy, “Parametric imaging of viscoelasticity using optical coherence elastography”, Physics in Medicine and Biology, 60:2293-2307. 2015. PMID: 25715798
    14. P. Gong, L. Chin, S. Es’haghian, Y.M. Liew, F.M. Wood, D.D. Sampson, R.A. McLaughlin, “Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking,” J. Biomedical Optics, 19(12):126014, 2014. PMID: 25539060
    15. R.A. McLaughlin, P.B. Noble, D.D. Sampson, “Optical coherence tomography in respiratory science and medicine: from airways to alveoli,” Physiology, 29(5):369-380, 2014. doi:10.1152/physiol.00002.2014, PMID: 25180266
    16. B.F. Kennedy, R.A. McLaughlin, K.M. Kennedy, L. Chin, A. Curatolo, A. Tien, B. Latham, C.M. Saunders, D.D. Sampson, “Optical coherence micro-elastography: mechanical-contrast imaging of tissue microstructure,” Biomedical Optics Express, 5(7):2113-2124, 2014. PMID: 25071952
    17. B.C. Quirk, R.A. McLaughlin, A.M. Pagnozzi, B.F. Kennedy, P.B. Noble, D.D. Sampson, “An optofluidic needle probe integrating targeted delivery of fluid with optical coherence tomography imaging,” Optics Letters, 10(39):2888-2891, 2014. PMID: 24978229
    18. P. Gong, R.A. McLaughlin, Y.M. Liew, P.R.T. Munro, F.M. Wood, D.D. Sampson, “Assessment of human burn scars with optical coherence tomography by imaging the attenuation coefficient of tissue after vascular masking,” J. Biomedical Optics, 19(2):021111, 2014. PMID: 24192908
    19. L. Scolaro, R.A. McLaughlin, B.F. Kennedy, C.S. Saunders, D.D. Sampson, “A review of optical coherence tomography in breast cancer,” Photonics & Lasers in Medicine, 3(3):225-240, 2014, DOI 10.1515/plm-2014-0013
    20. L. Chin, B.F. Kennedy, K.M. Kennedy, P. Wijesinghe, G.J. Pinniger, J.R. Terrill, R.A. McLaughlin, D.D. Sampson, “Three-dimensional optical coherence microelastography of skeletal muscle tissue,” Biomedical Optics Express, 5(9):3090-3102, 2014. DOI:10.1364/BOE.5.003090, PMID: 25401023
    21. L. Chin, A. Curatolo, B.F. Kennedy, B.J. Doyle, P.R.T. Munro, R.A. McLaughlin, D.D. Sampson, “Analysis of image formation in optical coherence elastography using a multiphysics approach,” Biomedical Optics Express, 5(9):2913-2930, 2014. PMID: 25401007
    22. K.M. Kennedy, S. Es’haghian, L. Chin, R.A. McLaughlin, D.D. Sampson, B.F. Kennedy, “Optical palpation: optical coherence tomography-based tactile imaging using a compliant sensor,” Optics Letters, 39(10):3014-3017, 2014. PMID: 24978261
    23. X. Yang, D. Lorenser, R.A. McLaughlin, R.W. Kirk, M. Edmond, M.C. Simpson, M.D. Grounds, D.D. Sampson, “Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe,” Biomedical Optics Express, 5(1):136-148, 2014. PMID: 24466482
    24. A.M. Pagnozzi, R.W. Kirk, B.F. Kennedy, D.D. Sampson, R.A. McLaughlin,  “Automated quantification of lung structures from optical coherence tomography images,” Biomedical Optics Express, 4(11):2383-2395, 2013. PMID: 24298402
    25. K.M. Kennedy, R.A. McLaughlin, B.F. Kennedy, A. Tien, B. Latham, C. Saunders, D.D. Sampson, “Needle optical coherence elastography for the measurement of microscale mechanical contrast deep within human breast tissues”, J. Biomedical Optics, 18(12):121510, 2013. PMID: 24365955
    26. X. Yang, L. Chin, B.R. Klyen, T. Shavlakadze, R.A. McLaughlin, M.D. Grounds, D.D. Sampson, “Quantitative assessment of muscle damage in the mdx mouse model of Duchenne muscular dystrophy using polarization-sensitive optical coherence tomography,” J. Applied Physiology, 115(9):1393-1401, 2013. PMID: 23990241
    27. L. Chin, X. Yang, R.A. McLaughlin, P.B. Noble, D.D. Sampson, “En face parametric imaging of tissue birefringence using polarization-sensitive optical coherence tomography,” J. Biomedical Optics, 18(6):066005, 2013. PMID: 23733021
    28. D. Lorenser, B.C. Quirk, M. Auger, W-J. Madore, R.W. Kirk, N. Godbout, D.D. Sampson, C. Boudoux, R.A. McLaughlin, “Dual-modality needle probe for combined fluorescence imaging and three dimensional optical coherence tomography,” Optics Letters, 38(3):266-268, 2013. PMID: 23381406
    29. Y.M. Liew, R.A. McLaughlin, P. Gong, F.M. Wood, D.D. Sampson, “In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography,” J. Biomedical Optics, 18(6):061213, 2013. PMID: 23174911
    30. R.A. McLaughlin, X. Yang, B.C. Quirk, D. Lorenser, R.W. Kirk, P.B. Noble, D.D. Sampson, “Static and dynamic imaging of alveoli using optical coherence tomography needle probes,” J. Applied Physiology, 113(6):967-974, 2012. PMID: 22773771
    31. L. Scolaro, D. Lorenser, R.A. McLaughlin, B.C. Quirk, R.W. Kirk, D.D. Sampson, “High-sensitivity anastigmatic imaging needle for optical coherence tomography,” Optics Letters, 37(24):5247-5249, 2012. PMID: 23258067
    32. A. Curatolo*, R.A. McLaughlin*, B.C. Quirk, R.W. Kirk, A.G. Bourke, B.A. Wood, P.D. Robbins, C.M. Saunders, D.D. Sampson, “Ultrasound-guided optical coherence tomography needle probe for the assessment of breast cancer tumor margins,” American Journal of Roentgenology, 199(4):W520-W522, 2012. PMID: 22997403. *These authors contributed equally to this work.
    33. R.A. McLaughlin, B.C. Quirk, A. Curatolo, R.W. Kirk, L. Scolaro, D.  Lorenser, P.D. Robbins, B.A. Wood, C.M. Saunders, D.D. Sampson, “Imaging of Breast Cancer with Optical Coherence Tomography Needle Probes: Feasibility and Initial Results,” IEEE J. Selected Topics in Quantum Electronics, 18(3):1184-1191, 2012.
    34. B.F. Kennedy, S.H. Koh, R.A. McLaughlin, Kelsey M. Kennedy, P.R.T. Munro, D.D. Sampson, “Strain estimation in phase-sensitive optical coherence elastography,” Biomedical Optics Express, 3(8):1865-1879, 2012. PMID: 22876350.
    35. Y.M. Liew, R.A. McLaughlin, F.M. Wood, D.D. Sampson, “Motion correction of in vivo three-dimensional optical coherence tomography of human skin using a fiducial marker,” Biomedical Optics Express, 3(8):1774-1786, 2012. PMID: 22876343
    36. B.Y. Yeo, R.A. McLaughlin, R.W. Kirk, D.D. Sampson, “Enabling freehand lateral scanning of optical coherence tomography needle probes with a magnetic tracking system,” Biomedical Optics Express, 3(7):1565-1578, 2012. PMID: 22808429
    37. K.M. Kennedy, B.F. Kennedy, R.A. McLaughlin, D.D. Sampson, “Needle optical coherence elastography for tissue boundary detection”, Optics Letters, 37(12):2310-2312, 2012. PMID: 24365955
    38. L. Scolaro, R.A. McLaughlin, B.R. Klyen, B.A. Wood, P.D. Robbins, C.M. Saunders, S.L. Jacques, D.D. Sampson, “Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography,” Biomedical Optics Express, 3(2):366-379, 2012. PMID: 22312589
    39. Y.M. Liew, R.A. McLaughlin, F.M. Wood, D.D. Sampson, “Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo,” J. Biomedical Optics, 16(11): 116018, 2011. PMID: 22112123
    40. D. Lorenser, X. Yang, R.W. Kirk, B.C. Quirk, R.A. McLaughlin, D.D. Sampson, “Ultrathin side-viewing needle probe for optical coherence tomography,” Optics Letters, 36(19):3894-3896, 2011. PMID: 21964133
    41. B.C. Quirk*, R.A. McLaughlin*, A. Curatolo, R.W. Kirk, P.B. Noble, D.D. Sampson, “In situ imaging of lung alveoli with an optical coherence tomography needle probe,” J. Biomedical Optics, 16(3):036009, 2011. PMID: 21456872. *These authors contributed equally to this work.
    42. J.P. Williamson, R.A. McLaughlin, W.J. Noffsinger, A.L. James, V.A. Baker, A. Curatolo, J.J. Armstrong, A. Regli, K.L. Shepherd, G.B. Marks, D.D. Sampson, D.R. Hillman, P.R. Eastwood, "Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography," American Journal of Respiratory and Critical Care Medicine, 183:612-619, 2011. PMID: 20851930
    43. R.A. McLaughlin, L. Scolaro, P. Robbins, S. Hamza, C. Saunders, D.D. Sampson, “Imaging of human lymph nodes using optical coherence tomography: potential for staging cancer,” Cancer Research, 70(7):2579-2584, 2010. PMID: 20233873
    44. J.P. Williamson, J.J. Armstrong, R.A. McLaughlin, P.B. Noble, A.R. West, S. Becker, A. Curatolo, W.J. Noffsinger, H.W. Mitchell, M.J. Phillips, D.D. Sampson, D.R. Hillman, P.R. Eastwood, “Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography,” European Respiratory J., 35(1):34-41, 2010. PMID: 19541718
    45. R.A. McLaughlin, L. Scolaro, P. Robbins, C. Saunders, S.L. Jacques, D.D. Sampson, “Parametric imaging of cancer with optical coherence tomography,” J. Biomedical Optics, 15(4): 046029, 2010. PMID: 20799831
    46. R.A. McLaughlin, D.D. Sampson, “Clinical applications of fiber-optic probes in optical coherence tomography,” Optical Fiber Technology, 16(6):467-475, 2010
    47. B. Lau, R.A. McLaughlin, A. Curatolo, R.W. Kirk, D.K. Gerstmann, D.D. Sampson, “Imaging true 3D endoscopic anatomy by incorporating magnetic tracking with optical coherence tomography: proof-of-principle for airways,” Optics Express, 18(26):27173-27180, 2010. PMID: 21196994
    48. B.F. Kennedy, S. Loitsch, R.A. McLaughlin, L. Scolaro, P. Rigby, D.D. Sampson, “Fibrin phantom for use in optical coherence tomography,” J. Biomedical Optics, 15(3):030507, 2010. PMID: 20614992
    49. J.P. Williamson, R.A. McLaughlin, M.J. Phillips, A. Curatolo, J.J. Armstrong, K.J. Maddison, R.E. Sheehan, D.D. Sampson, D.R. Hillman, P.R. Eastwood, “Feasibility of applying real-time optical imaging during bronchoscopic interventions for central airway obstruction,” Journal of Bronchology and Interventional Pulmonology, 17(4):307-316, 2010. PMID: 23168951
    50. P.B. Noble, R.A. McLaughlin, A.R. West, S. Becker, J.J. Armstrong, P.K. McFawn, P.R. Eastwood, D.R. Hillman, D.D. Sampson, H.W. Mitchell, “Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography,” Respiratory Research, 11(9), 2010. PMID: 20092657
    51. P.B. Noble, A.R. West, R.A. McLaughlin, J.J. Armstrong, S. Becker, P.K. McFawn, J.P. Williamson, P.R. Eastwood, D.R. Hillman, D.D. Sampson, H.W. Mitchell, “Airway narrowing assessed by anatomical optical coherence tomography in vitro: Dynamic airway wall morphology and function,” J. Applied Physiology, 108:401-411, 2010. PMID: 19910337
    52. J.P. Williamson, R.A. McLaughlin, M.J. Phillips, J.J. Armstrong, S. Becker, J.H. Walsh, D.D. Sampson, D.R. Hillman, P.R. Eastwood, “Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy,” Chest, 136(1):272-276, 2009. PMID: 19225058
    53. R.A. McLaughlin, J.J. Armstrong, S. Becker, J.H. Walsh, A. Jain, D.R. Hillman, P.R. Eastwood, D.D. Sampson, “Respiratory gating of anatomical optical coherence tomography images of the human airway,” Optics Express, 17(8):6568-6577, 2009. PMID: 19365482
    54. B.F. Kennedy, T.R. Hillman, R.A. McLaughlin, B.C. Quirk, D.D. Sampson, “In vivo dynamic optical coherence elastography using a ring actuator,” Optics Express, 17(24):21762-21772, 2009. PMID: 19997419
    55. R.A. McLaughlin, J.P. Williamson, M.J. Phillips, J.J. Armstrong, S. Becker, D.R. Hillman, P.R. Eastwood, D.D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Optics Express, 16(22):17521-17529, 2008. PMID: 18958032
    56. R.A. McLaughlin, “Extracting Transmission Lines from Airborne LIDAR data,” IEEE Geoscience and Remote Sensing Letters, 3(2):222-226, 2006
    57. R.A. McLaughlin, J. Hipwell, D.J. Hawkes, J.A. Noble, J.V. Byrne, T.C. Cox, “A comparison of a similarity-based and a feature-based 2-D-3-D registration method for neurointerventional use,” IEEE Trans. Medical Imaging, 24(8):1058-1066, 2005. PMID: 16092337
    58. X.B. Pan, T.G. Wright, F.J. Leong, R.A. McLaughlin, J.M. Declerck, D.H.S. Silverman, “Improving influx constant and ratio estimation in FDOPA brain PET analysis for Parkinson's disease,” J. Nuclear Medicine, 46(10):1737-1744, 2005. PMID: 16204725
    59. J.H. Hipwell, G.P. Penney, R.A. McLaughlin, K. Rhode, P. Summers, T.C. Cox, J.V. Byrne, J.A. Noble, D.J. Hawkes, “Intensity based 2-D-3-D registration of cerebral angiograms,” IEEE Trans. Medical Imaging, 22(11):1417-1426, 2003. PMID: 14606675
    60. R.A. McLaughlin, M.D. Alder, “The Hough transform versus the UpWrite,” IEEE Trans. Pattern Analysis and Machine Intelligence, 20(4):396-400, 1998
    61. R.A. McLaughlin, “Randomized Hough transform: Improved ellipse detection with comparison,” Pattern Recognition Letters, 19(3):299-305, 1998
    62. R.A. McLaughlin, M.D. Alder, C.J.S. deSilva, “Inference of structure: hands,” Pattern Recognition Letters, 15(10):957-962, 1994

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

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Entry last updated: Thursday, 9 Aug 2018

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