Candida bracarensis

RG-2 organism.

Culture: 
Colonies (SDA) white to cream-coloured smooth, glabrous, yeast-like.

Microscopy: 
Ellipsoidal budding blastoconidia, 3.9-6 x 2-4 µm in size. No pseudohyphae or chlamydospores produced.

India ink preparation: 
Negative - no capsules present.

Dalmau plate culture: 
No pseudohyphae produced.

Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow, nd No Data
Germ Tube - L-Sorbose - L-Arabinose - D-Glucitol -
Fermentation   Sucrose - D-Arabinose - 𝝰-M-D-Glucoside -
Glucose + Maltose - D-Ribose - D-Gluconate +
Galactose - Cellobiose - L-Rhamnose - DL-Lactate -
Sucrose - Trehalose + D-Glucosamime - myo-Inositol -
Maltose - Lactose - N-A-D-glucosamine - 2-K-D-Gluconate -
Lactose - Melibiose - Glycerol v D-Glucuronate -
Trehalose s Raffinose - Erythritol - Nitrate -
Assimilation   Melezitose - Ribitol - Urease -
Glucose + Soluble Starch - Galactitol - 0.1% Cycloheximide -
Galactose - D-Xylose - D-Mannitol - Growth at 40C +

Key features: 
C. bracarensis has variable API 20C patterns that overlap with C. nivariensis and some C. glabrata isolates, and has variable results with a rapid trehalose assay. Note: C. glabrata produces mauve-coloured colonies on CHROMagar, whereas isolates of C. bracarensis, C. nivariensis, C. norvegensis and C. inconspicua produce white colonies on CHROMagar (Alcoba-Flórez et al. 2005, Bishop et al. 2008).

Antifungal susceptibility: Candida bracarensis (Australian national data); MIC µg/mL.
Antifungal No ≤0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 ≥64
AMB 10           1 2 3 3 1        
FLU 10               1 2 4 2 1    
ISAV 1     1                      
VORI 10   1   3 5 1                
POSA 10       1 2 6 1              
ITRA 10         1 6 3              
ANID 10   2 3 5                    
MICA 10 3 6 1                      
CAS 10       5 4 1                
5FC 10       1 2 4 2 1            

Go to Candida glabrata  Go to Candida nivariensis  Back to Candida