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Professor Prash Sanders

Telephone +61 8 8222 2723
Position Director - Centre for Heart Rhythm Disorders
Email prash.sanders@adelaide.edu.au
Fax +61 8 8222 2722
Building RAH - McEwin Bldg Department of Cardiology
Floor/Room 5
Campus Royal Adelaide Hospital
Org Unit Medicine

To link to this page, please use the following URL:
http://www.adelaide.edu.au/directory/prash.sanders

Biography/ Background

Professor Sanders is a clinical academic based at the University of Adelaide, Royal Adelaide Hospital and the South Australian Health and Medical Research Insititute. He is the Director of the Centre for Heart Rhythm Disorders at the University of Adelaide; Director of Cardiac Electrophysiology and Pacing at the Royal Adelaide Hospital; and the Group Leader for Heart Rhythm Disorders at SAHMRI.

He graduated from the University of Adelaide with Honours, awarded several prizes and named on the Dean’s list for academic merit. He trained as a Cardiologist was at the Royal Adelaide Hospital before sub-specialising in Cardiac Electrophysiology at the Royal Melbourne Hospital. His doctoral studies at the University of Melbourne were under the mentorship of Professor Jonathan Kalman. His postdoctoral studies were with the team of Professor Michel Haissaguerre at the Hôpital Cardiologique du Haut-Lévêque and Université Victor Segalen Bordeaux II, Bordeaux, France.

In 2005 he moved back to Adelaide and has established a formidable team of clinicians and researchers who span the spectrum of research into heart rhythm disorders; ranging from computer modelling of cardiac arrhythmias, cellular electrophysiology, small and large animal models of disease to evaluate arrhythmia mechanisms, clinical mechanistic, outcome and more recently population based studies. The group has an established clinical trials program and is involved in development of novel technologies.

Awards & Achievements

Recent Award 

  1. National Health and Medical Research Council of Australia Achievement Award. Highest Ranked Practitioner Fellowship 2013.

  2. Scopus Young Australian Medical & Medical Sciences Researcher of the Year 2010.

Recent Achievements by the Centre for Heart Rhythm Disorders (2014-2015)

  1. Dr. Rajeev K. Pathak, Late-breaking clinical trial presentation at the American College of Cardiology.

  2. Dr. Shivshankar Thanigaimani, Dean’s Commendation for Doctoral Thesis Excellence.

  3. Dr. Rajiv Mahajan, Eric N. Prystowsky Fellows Clinical Research Award, Heart Rhythm Society.

  4. Dr. Rajiv Mahajan, Doctoral Research Medal from the University of Adelaide.

  5. Dr Jeroen Hendriks appointed to the Derek Frewin Lectureship

  6. Dr. Geetanjali Rangnekar, PhD Awarded.

  7. Dr. Muayad Alasady, PhD Awarded.

  8. Dr. Shivshankar Thanigaimani, PhD Awarded.

  9. Dr Carlee Schulz, Dean’s Commendation for Doctoral Thesis Excellence.

  10. Dr Carlee Schulz, PhD Awarded.

  11. Dr Rajiv Mahajan, Leo J. Mahar Lectureship, University of Adelaide.

  12. Ms. Geetanjali Rangnekar, Best Poster Presentation Award, ASMR Scientific Meeting.

  13. Dr Rajiv Mahajan, Dean’s Commendation for Doctoral Thesis Excellence.

  14. Dr Rajiv Mahajan, PhD Awarded.

  15. Mr Darius Chapman, Finalist for the Affiliate Prize, Annual Scientific Sessions of the Heart Rhythm Society.

  16. Ms. Lauren Wilson, Finalist for the Affiliate Prize, Annual Scientific Sessions of the Heart Rhythm Society.

  17. Dr Rajeev Pathak, Eric Prystowshy Clinical Research Award, Annual Scientific Sessions of the Heart Rhythm Society.

Publications

Professor Sanders has published over 280 peer-reviewed publications and has an H index of 59. Some of his recent publications are shown below. For a review of publication history: https://orcid.org/0000-0003-3803-8429

Publications from 2014

  1. McLellan AJA, Ling LH, Azzopardi S, Lee GA, Lee G, Kumar S, Wong MCG, Walters TE, Lee JM, Looi KL, Halloran K, Stiles MK, Lever NA, Fynn SP, Heck PM, Sanders P, Morton JB, Kalman JM, Kistler PM. A minimal or maximal ablation strategy to achieve pulmonary vein isolation for paroxysmal atrial fibrillation: a prospective multi-centre randomized coltrolled trial (The Minimax Study). European Heart Journal (In Press).
  2. Wong MCG, Kalman JM, Pedagogos E, Toussaint N, Vohra JK, Sparks PB, Sanders P, Kistler PM, Halloran K, Lee G, Joseph SA, Morton JB. Bradycardia and asystole is the predominant mechanism of sudden cardiac death in patients with chronic kidney disease. Journal of the American College of Cardiology (In Press).
  3. Pathak RK, Middeldorp ME, Meredith M, Mehta A, Mahajan R, Wong CX, Twomey D, Elliott A, Kalman JM, Abhayaratna WP, Lau DH, Sanders P. Long-term Effect of Goal directed weight management in an Atrial fibrillation Cohort: a long-term follow up study (LEGACY Study). Journal of the American College of Cardiology (In Press).
  4. Pürefellner H, Sanders P, Pokushalov E, Di Bacco M, Bergemann T, Zielinkski TM, Dekker LRC. Miniaturized Reveal LinqTM insertable cardiac monitoring system: first in man experience. Heart Rhythm (In Press).
  5. Walters TE, Lee G, Morris G, Spence S, Larobina M, Atkinson V, Antippa P, Goldblatt J, Royse A, O'Keefe M, Sanders P, Morton JB, Kistler PM, Kalman JM. Temporal stability of rotors and atrial activation patterns in persistent human atrial fibrillation: a high density epicardial mapping study of prolonged recordings. Journal of the American College of Cardiology: Clinical Electrophysiology (In Press).
  6. Wong CX, Lee SW, Gan S, Mahajan R, Rangnekar G, Pathak RK, Twomey D, Schultz C, Ganesan AN, Brooks AG, Roberts-Thomson KC, Brown A, Lau DH, Sanders P. Underuse and overuse of anticoagulation for atrial fibrillation: a study in Indigenous and non-Indigenous Australians. International Journal of Cardiology (In Press).
  7. Lau DH, Maesen B, Zeemering S, Kuklik P, van Hunnik A, Lankveld T, Bidar E, Verheule S, Nijs J, Maessen J, Crijns H, Sanders P, Schotten U. Indices of bipolar complex fractionated atrial electrograms correlate poorly with each other and atrial fibrillation substrate complexity. Heart Rhythm (In Press).
  8. Tse HF, Turner S, Sanders P, Okuyama Y, Fujiu K, Cheung CW, Russo M, Green MD, Yiu KH, Siu CW. Thoracic Spinal Cord Stimulation for HEArt failure as a Restorative Treatment (SCS HEART Study): first-in-man experience. Heart Rhythm 2015; 12: 588-595.
  9. Ganesan AN, Nandal S, Lüker J, Pathak RK, Mahajan R, Twomey D, Lau DH, Sanders P. Catheter ablation of atrial fibrillation in patients with concomitant left ventricular impairment: a systematic review of the efficacy and effect on ejection fraction. Heart, Lung and Circulation 2015; 24: 270-280.
  10. Pathak RK, Mahajan R, Lau DH, Sanders P. The implications of obesity for cardiac arrhythmia mechanisms and management. Canadian Journal of Cardiology 2015; 31: 203-210.
  11. Mahajan R, Lau DH, Sanders P. Impact of obesity on cardiac metabolism, fibrosis and function. Trends in Cardiovascular Medicine 2015; 25: 119-126.
  12. Twomey DJ, Sanders P, Roberts-Thomson KC. Atrial macro-reentry in congenital heart disease. Current Cardiology Reviews 2015; 11: 141-148.
  13. Ganesan AN, Puklik P, Gharaviri A, Brooks AG, Chapman D, Lau DH, Roberts-Thomson KC, Sanders P. Origin and characteristics of high Shannon entrop at the pivot of locally stable rotors: insights from computational simulation. PLoS One 2014; 9: e110662.
  14. Walters TE, Lee G, Spence S, Larobina M, Atkinson V, Antippa P, Goldblatt J, O'Keefe M, Sanders P, Kistler PM, Kalman JM. Acute atrial stretch results in conduction slowing and complex signals at the pulmonary vein to left atrial junction: insights into the mechanism of pulmonary vein arrhythmogenesis. Circulation, Arrhythmia and Electrophysiolohy 2014; 7: 1189-1197.
  15. Wong GR, Lau DH, Baillie TJ, Middeldorp ME, Steele PM, Sanders P. Novel use of sildenafil in the management of pulmonary hypertension due to post-catheter ablation ‘stiff left atrial syndrome'. International Journal of Cardiology 2014; 181C: 55-56.
  16. Pathak RK, Middeldorp ME, Lau DH, Mehta AB, Mahajan R, Twomey D, Alasady M, Hanley L, Antic NA, McEvoy RD, Kalman JM, Abhayaratna WP, Sanders P. Aggressive Risk factor REduction STudy for Atrial Fibrillation (The ARREST-AF cohort study): implications for the outcomes of ablation. Journal of the American College of Cardiology 2014; 64: 2222-2231.
  17. Wong CX, Brooks AG, Cheng YH, Lau DH, Rangnekar G, Roberts-Thomson KC, Kalman JM, Brown A, Sanders P. Atrial fibrillation in indigenous and non-indigenous Australians: a cross-sectional study. British Medical Journal Open 2014; 4: e006242.
  18. Zaman S, Sivagangabalan G, Chik W, Stafford W, Hayes J, Denman R, Young G, Sanders P, Kovoor P. Ventricular tachyarrhythmia recurrence in primary versus secondary implantable cardioverter-defibrillator patients and role of electrophysiology study. Journal of Interventional Cardiovascular Electrophysiology 2014; 41: 195-202.
  19. Lau DH, Kalman JM, Sanders P. Management of recent-onset sustained atrial fibrillation: pharmacologic and nonpharmacologic strategies. Clinical Therapeutics 2014; 36: 1151-1159.
  20. Lim HS, Willoughby SR, Schultz C, Chakrabarty A, Alasady M, Lau DH, Roberts-Thomson KC, Worthley MI, Young GD, Sanders P. Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation. Heart Rhythm 2014; 11: 1912-1918.
  21. Marwick TH, Sanders P. A foregone conclusion? Risk stratification in pacemaker-associated endocarditis. Journal of the American College of Cardiology Imaging 2014; 7: 550-552.
  22. Wong CX, Lau DH, Sanders P. Atrial fibrillation epidemic and hospitalization: how to turn the rising tide? Circulation 2014; 129: 2361-2363.
  23. Mahajan R, Lau DH. Sanders P. Biomarkers and atrial fibrillation: is it prime time yet? Heart 2014; 100: 1151-1152.
  24. Schultz CD, Rangneker G, Lim HS, Fraudeau A, Young GD, Roberts-Thomson KC, John B, Worthley MI, Sanders P, Willoughby SR. Characterization of thrombogenic, endothelial and inflammatory markers in supraventricular tachycardia: a study in patients with structurally normal hearts. Clinical and Experimental Pharmacology and Physiology 2014; 41: 551-557.
  25. Kuklik P, Molaee P, Podziemski P, Ganesan AN, Brooks AG, Worthley SG, Sanders P. Quantitative description of the 3D regional mechanics of the left atrium using cardiac magnetic resonance imaging. Physiological Measures 2014; 35: 763-775.
  26. Hatem SN, Sanders P. Epicardial adipose tissue and atrial fibrillation. Cardiovascular Research 2014; 102: 205-213.
  27. Crijns HJ, Weijs B, Fairley AM, Lewalter T, Maggioni AP, Martin A, Ponikowski P, Rosenqvist M, Sanders P, Scanavacca M, Bash LD, Chazelle F, Bernhardt A, Gitt AK, Lip GY, Le Heuzey JY. Contemporary real life cardioversion of atrial fibrillation: results from the multinational RHYTHM-AF study. International Journal of Cardiology 2014; 172: 588-594.
  28. Lim HS, Schultz C, Dang J, Alasady M, Lau DH, Brooks AG, Wong CX, Robert-Thomson KC, Young GD, Worthley MI, Sanders P*, Willoughby SR*. Time course of inflammation, myocardial injury, and prothrombotic response following radiofrequency catheter ablation for atrial fibrillation. Circulation, Arrhythmia and Electrophysiology 2014; 7: 83-89. *denoted equal contribution
  29. Verma A, Sanders P, Champagne J, Macle L, Nair GM, Calkins H, Wilber DJ. Selective CAFÉ targeting for atrial fibrillation study (SELECT AF): a multicenter, randomized trial. Circulation, Arrhythmia and Electrophysiology 2014; 7: 55-62.
  30. Nayyar S, Wilson L, Ganesan AN, Sullivan T, Kuklik P, Chapman D, Brooks AG, Mahajan R, Baumert M, Young GD, Sanders P, Roberts-Thomson KC. High density mapping of ventricular scar: a comparison of ventricular tachycardia supporting channels with channels that do not support VT. Circulation, Arrhythmia and Electrophysiology 2014; 7: 90-98.
  31. Metcalf RG, Skuladottir GV, Indridason OS, Sullivan TR, Bjorgvinsdottir, Sanders P, Arnar DO, Gibson RA, Heidarsdottir R, Cleland LG, Palsson R, Fraquharson AL, Young GD, James MJ. U-shaped relationship between tissue docosahexaenoic acid and atrial fibrillation following cardiac surgery. European Journal of Clinical Nutrition 2014; 68: 114-118.
  32. Lee G, Kumar S, Teh A, Madry A, Spence S, Larobina M, Goldblatt J, Brown R, Atkinson V, Moten S, Morton JB, Sanders P, Kistler PM, Kalman JM. Epicardial wave mapping in human long-lasting persistent AF: transient rotors, complex wavefronts and disorganized activity. European Heart Journal 2014; 35: 86-97.


 

 

 

 

 

Entry last updated: Friday, 10 Apr 2015

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