Professor Prash Sanders
Sanders is a clinical academic based at the University of Adelaide, Royal
Adelaide Hospital and the South Australian Health and Medical Research Insititute.
He is the Director of the Centre for Heart Rhythm Disorders at the University
of Adelaide; Director of Cardiac Electrophysiology and Pacing at the Royal
Adelaide Hospital; and the Group Leader for Heart Rhythm Disorders at SAHMRI.
from the University of Adelaide with Honours, awarded several prizes and named
on the Dean’s list for academic merit. He trained as a Cardiologist was at the
Royal Adelaide Hospital before sub-specialising in Cardiac Electrophysiology at
the Royal Melbourne Hospital. His doctoral studies at the University of
Melbourne were under the mentorship of Professor Jonathan Kalman. His postdoctoral
studies were with the team of Professor Michel Haissaguerre at the Hôpital
Cardiologique du Haut-Lévêque and Université
Victor Segalen Bordeaux II, Bordeaux, France.
In 2005 he moved back
to Adelaide and has established a formidable team of clinicians and researchers
who span the spectrum of research into heart rhythm disorders; ranging from
computer modelling of cardiac arrhythmias, cellular electrophysiology, small
and large animal models of disease to evaluate arrhythmia mechanisms, clinical
mechanistic, outcome and more recently population based studies. The group has
an established clinical trials program and is involved in development of novel
Awards & Achievements
Health and Medical Research Council of Australia Achievement Award. Highest
Ranked Practitioner Fellowship 2013.
Australian Medical & Medical Sciences Researcher of the Year 2010.
Recent Achievements by the Centre for Heart Rhythm Disorders (2014-2015)
Rajeev K. Pathak, Late-breaking clinical trial presentation at the American
College of Cardiology.
Thanigaimani, Dean’s Commendation for Doctoral Thesis Excellence.
Rajiv Mahajan, Eric N. Prystowsky Fellows Clinical Research Award, Heart Rhythm
Rajiv Mahajan, Doctoral Research Medal from the University of Adelaide.
Jeroen Hendriks appointed to
the Derek Frewin Lectureship
Dr. Geetanjali Rangnekar, PhD Awarded.
Dr. Muayad Alasady, PhD Awarded.
Thanigaimani, PhD Awarded.
Dr Carlee Schulz, Dean’s Commendation for Doctoral
Dr Carlee Schulz, PhD Awarded.
Dr Rajiv Mahajan, Leo J. Mahar Lectureship, University
Ms. Geetanjali Rangnekar, Best Poster Presentation
Award, ASMR Scientific Meeting.
Dr Rajiv Mahajan, Dean’s Commendation for Doctoral
Dr Rajiv Mahajan, PhD Awarded.
Mr Darius Chapman, Finalist for the Affiliate Prize,
Annual Scientific Sessions of the Heart Rhythm Society.
Ms. Lauren Wilson, Finalist for the Affiliate Prize,
Annual Scientific Sessions of the Heart Rhythm Society.
Dr Rajeev Pathak, Eric Prystowshy Clinical Research
Award, Annual Scientific Sessions of the Heart Rhythm Society.
Sanders has published over 280 peer-reviewed publications and has an H index of
59. Some of his recent publications are shown below. For a review of
publication history: https://orcid.org/0000-0003-3803-8429
- McLellan AJA, Ling LH, Azzopardi S, Lee
GA, Lee G, Kumar S, Wong MCG, Walters TE, Lee JM, Looi KL, Halloran K,
Stiles MK, Lever NA, Fynn SP, Heck PM, Sanders P, Morton JB, Kalman
JM, Kistler PM. A minimal or maximal ablation strategy to achieve
pulmonary vein isolation for paroxysmal atrial fibrillation: a prospective
multi-centre randomized coltrolled trial (The Minimax Study). European
Heart Journal (In Press).
- Wong MCG, Kalman JM, Pedagogos E,
Toussaint N, Vohra JK, Sparks PB, Sanders P, Kistler PM, Halloran
K, Lee G, Joseph SA, Morton JB. Bradycardia and asystole is the
predominant mechanism of sudden cardiac death in patients with chronic
kidney disease. Journal of the American College of Cardiology (In
- Pathak RK, Middeldorp ME, Meredith M,
Mehta A, Mahajan R, Wong CX, Twomey D, Elliott A, Kalman JM, Abhayaratna
WP, Lau DH, Sanders P. Long-term Effect of Goal directed weight
management in an Atrial fibrillation Cohort: a long-term follow up study
(LEGACY Study). Journal of the American College of Cardiology (In
- Pürefellner H, Sanders P,
Pokushalov E, Di Bacco M, Bergemann T, Zielinkski TM, Dekker LRC.
Miniaturized Reveal LinqTM insertable cardiac monitoring system: first in
man experience. Heart Rhythm (In Press).
- Walters TE, Lee G, Morris G, Spence S,
Larobina M, Atkinson V, Antippa P, Goldblatt J, Royse A, O'Keefe M, Sanders
P, Morton JB, Kistler PM, Kalman JM. Temporal stability of rotors and
atrial activation patterns in persistent human atrial fibrillation: a high
density epicardial mapping study of prolonged recordings. Journal of
the American College of Cardiology: Clinical Electrophysiology (In
- Wong CX, Lee SW, Gan S, Mahajan R,
Rangnekar G, Pathak RK, Twomey D, Schultz C, Ganesan AN, Brooks AG,
Roberts-Thomson KC, Brown A, Lau DH, Sanders P. Underuse and
overuse of anticoagulation for atrial fibrillation: a study in Indigenous
and non-Indigenous Australians. International Journal of Cardiology
- Lau DH, Maesen B, Zeemering S, Kuklik P,
van Hunnik A, Lankveld T, Bidar E, Verheule S, Nijs J, Maessen J, Crijns
H, Sanders P, Schotten U. Indices of bipolar complex fractionated
atrial electrograms correlate poorly with each other and atrial
fibrillation substrate complexity. Heart Rhythm (In Press).
- Tse HF, Turner S, Sanders P,
Okuyama Y, Fujiu K, Cheung CW, Russo M, Green MD, Yiu KH, Siu CW. Thoracic
Spinal Cord Stimulation for HEArt failure as a Restorative Treatment (SCS
HEART Study): first-in-man experience. Heart Rhythm 2015; 12: 588-595.
- Ganesan AN, Nandal S, Lüker J, Pathak
RK, Mahajan R, Twomey D, Lau DH, Sanders P. Catheter ablation of
atrial fibrillation in patients with concomitant left ventricular
impairment: a systematic review of the efficacy and effect on ejection
fraction. Heart, Lung and Circulation 2015; 24: 270-280.
- Pathak RK, Mahajan R, Lau DH, Sanders
P. The implications of obesity for cardiac arrhythmia mechanisms and
management. Canadian Journal of Cardiology 2015; 31: 203-210.
- Mahajan R, Lau DH, Sanders P.
Impact of obesity on cardiac metabolism, fibrosis and function. Trends
in Cardiovascular Medicine 2015; 25: 119-126.
- Twomey DJ, Sanders P,
Roberts-Thomson KC. Atrial macro-reentry in congenital heart disease. Current
Cardiology Reviews 2015; 11: 141-148.
- Ganesan AN, Puklik P, Gharaviri A,
Brooks AG, Chapman D, Lau DH, Roberts-Thomson KC, Sanders P. Origin
and characteristics of high Shannon entrop at the pivot of locally stable
rotors: insights from computational simulation. PLoS One 2014; 9:
- Walters TE, Lee G, Spence S, Larobina M,
Atkinson V, Antippa P, Goldblatt J, O'Keefe M, Sanders P, Kistler
PM, Kalman JM. Acute atrial stretch results in conduction slowing and
complex signals at the pulmonary vein to left atrial junction: insights
into the mechanism of pulmonary vein arrhythmogenesis. Circulation,
Arrhythmia and Electrophysiolohy 2014; 7: 1189-1197.
- Wong GR, Lau DH, Baillie TJ, Middeldorp
ME, Steele PM, Sanders P. Novel use of sildenafil in the management
of pulmonary hypertension due to post-catheter ablation ‘stiff left atrial
syndrome'. International Journal of Cardiology 2014; 181C: 55-56.
- Pathak RK, Middeldorp ME, Lau DH, Mehta
AB, Mahajan R, Twomey D, Alasady M, Hanley L, Antic NA, McEvoy RD, Kalman
JM, Abhayaratna WP, Sanders P. Aggressive Risk factor REduction
STudy for Atrial Fibrillation (The ARREST-AF cohort study): implications
for the outcomes of ablation. Journal of the American College of
Cardiology 2014; 64: 2222-2231.
- Wong CX, Brooks AG, Cheng YH, Lau DH,
Rangnekar G, Roberts-Thomson KC, Kalman JM, Brown A, Sanders P.
Atrial fibrillation in indigenous and non-indigenous Australians: a
cross-sectional study. British Medical Journal Open 2014; 4: e006242.
- Zaman S, Sivagangabalan G, Chik W,
Stafford W, Hayes J, Denman R, Young G, Sanders P, Kovoor P.
Ventricular tachyarrhythmia recurrence in primary versus secondary
implantable cardioverter-defibrillator patients and role of
electrophysiology study. Journal of Interventional Cardiovascular
Electrophysiology 2014; 41: 195-202.
- Lau DH, Kalman JM, Sanders P.
Management of recent-onset sustained atrial fibrillation: pharmacologic
and nonpharmacologic strategies. Clinical Therapeutics 2014; 36:
- Lim HS, Willoughby SR, Schultz C,
Chakrabarty A, Alasady M, Lau DH, Roberts-Thomson KC, Worthley MI, Young
GD, Sanders P. Successful catheter ablation decreases platelet activation
and improves endothelial function in patients with atrial fibrillation. Heart
Rhythm 2014; 11: 1912-1918.
- Marwick TH, Sanders P. A foregone
conclusion? Risk stratification in pacemaker-associated endocarditis. Journal
of the American College of Cardiology Imaging 2014; 7: 550-552.
- Wong CX, Lau DH, Sanders P.
Atrial fibrillation epidemic and hospitalization: how to turn the rising
tide? Circulation 2014; 129: 2361-2363.
- Mahajan R, Lau DH. Sanders P.
Biomarkers and atrial fibrillation: is it prime time yet? Heart 2014;
- Schultz CD, Rangneker G, Lim HS,
Fraudeau A, Young GD, Roberts-Thomson KC, John B, Worthley MI, Sanders
P, Willoughby SR. Characterization of thrombogenic, endothelial and
inflammatory markers in supraventricular tachycardia: a study in patients
with structurally normal hearts. Clinical and Experimental Pharmacology
and Physiology 2014; 41: 551-557.
- Kuklik P, Molaee P, Podziemski P,
Ganesan AN, Brooks AG, Worthley SG, Sanders P. Quantitative
description of the 3D regional mechanics of the left atrium using cardiac
magnetic resonance imaging. Physiological Measures 2014; 35: 763-775.
- Hatem SN, Sanders P. Epicardial
adipose tissue and atrial fibrillation. Cardiovascular Research 2014;
- Crijns HJ, Weijs B, Fairley AM, Lewalter
T, Maggioni AP, Martin A, Ponikowski P, Rosenqvist M, Sanders P,
Scanavacca M, Bash LD, Chazelle F, Bernhardt A, Gitt AK, Lip GY, Le Heuzey
JY. Contemporary real life cardioversion of atrial fibrillation: results
from the multinational RHYTHM-AF study. International Journal of
Cardiology 2014; 172: 588-594.
- Lim HS, Schultz C, Dang J, Alasady M,
Lau DH, Brooks AG, Wong CX, Robert-Thomson KC, Young GD, Worthley MI, Sanders
P*, Willoughby SR*. Time course of inflammation, myocardial injury, and
prothrombotic response following radiofrequency catheter ablation for
atrial fibrillation. Circulation, Arrhythmia and Electrophysiology
2014; 7: 83-89. *denoted equal contribution
- Verma A, Sanders P, Champagne J,
Macle L, Nair GM, Calkins H, Wilber DJ. Selective CAFÉ targeting for
atrial fibrillation study (SELECT AF): a multicenter, randomized trial. Circulation,
Arrhythmia and Electrophysiology 2014; 7: 55-62.
- Nayyar S, Wilson L, Ganesan AN, Sullivan
T, Kuklik P, Chapman D, Brooks AG, Mahajan R, Baumert M, Young GD, Sanders
P, Roberts-Thomson KC. High density mapping of ventricular scar: a
comparison of ventricular tachycardia supporting channels with channels
that do not support VT. Circulation, Arrhythmia and Electrophysiology
2014; 7: 90-98.
- Metcalf RG, Skuladottir GV, Indridason
OS, Sullivan TR, Bjorgvinsdottir, Sanders P, Arnar DO, Gibson RA,
Heidarsdottir R, Cleland LG, Palsson R, Fraquharson AL, Young GD, James
MJ. U-shaped relationship between tissue docosahexaenoic acid and atrial
fibrillation following cardiac surgery. European Journal of Clinical
Nutrition 2014; 68: 114-118.
- Lee G, Kumar S, Teh A, Madry A, Spence
S, Larobina M, Goldblatt J, Brown R, Atkinson V, Moten S, Morton JB, Sanders
P, Kistler PM, Kalman JM. Epicardial wave mapping in human
long-lasting persistent AF: transient rotors, complex wavefronts and
disorganized activity. European Heart Journal 2014; 35: 86-97.
Entry last updated: Friday, 10 Apr 2015
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