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Professor Robert Norman
To link to this page, please use the following URL: Biography/ BackgroundRobert Norman holds a personal chair as Professor for Reproductive and Periconceptual Medicine at the University of Adelaide and is a subspecialist in reproductive medicine (CREI) and in endocrine biochemistry (FRCPA). He is Director of the Robinson Institute at the University of Adelaide, a collection of 350 researchers in reproductive health and regenerative medicine. He is leader of the NHMRC Program Grant on ‘Periconceptual origins of health and disease’ and has published over 300 peer-reviewed publications and one book. He serves on the editorial board of major journals. His major research contributions have been in IVF and reproductive endocrinology, particularly in PCOS, the effect of lifestyle on reproductive outcomes and periconception medicine. He is an active reproductive medicine specialist. He serves on the National Health and Medical Research Council’s research and embryo licensing committees. Qualifications1972 - BSc (Hons) Anatomical Sciences, First class, University of Birmingham 1974 - MB ChB (Hons), University of Birmingham 1983 - MD, University of Natal, Durban FRANZCOG, FRCPA, FRCPath, FRCOG, CREI Awards & Achievements
Research Interests
PublicationsRefereed Journal Articles 2013 Hart R, Norman RJ. ‘The longer-term health outcomes for children born as a result of IVF treatment. Part II: mental health and development outcomes', Hum Reprod Update. 2013 Feb 28. Hart R, Norman RJ. ‘The longer-term health outcomes for children born as a result of IVF treatment: Part I-General health outcomes', Hum Reprod Update. 2013 Feb 28. Butler MS, Yang X, Ricciardelli C, Liang X, Norman RJ, Tilley WD, Hickey TE. ‘Small glutamine-rich tetratricopeptide repeat-containing protein alpha is present in human ovaries but may not be differentially expressed in relation to polycystic ovary syndrome', Fertil Steril. 2013 Feb 20. Refereed Journal Articles 2012 Escobar-Morreale HF, Carmina E, Dewailly D, Gambineri A, Kelestimur F, Moghetti P, Pugeat M, Qiao J, Wijeyaratne CN, Witchel SF, Norman RJ. ‘Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society', Hum Reprod Update. 2012 Dec 18. Moran LJ, Norman RJ. ‘The effect of bariatric surgery on female reproductive function', J Clin Endocrinol Metab. 2012 Dec;97(12):4352-4. doi: 10.1210/jc.2012-3606. Hammarberg K, Setter T, Norman RJ, Holden CA, Michelmore J, Johnson L. ‘Knowledge about factors that influence fertility among Australians of reproductive age: a population-based survey', Fertil Steril. 2012 Nov 14. doi:pii: S0015-0282(12)02343-6. 10.1016/j.fertnstert.2012.10.031. Lim SS, Norman RJ, Davies MJ, Moran LJ. ‘The effect of obesity on polycystic ovary syndrome: a systematic review and meta-analysis', Obes Rev. 2013 Feb;14(2):95-109. doi: 10.1111/j.1467-789X.2012.01053. Moran LJ, Noakes M, Wittert GA, Clifton PM, Norman RJ. ‘Weight loss and vascular inflammatory markers in overweight women with and without polycystic ovary syndrome’, Reprod Biomed Online. 2012 Jul 26. Sullivan EA, Wang YA, Hayward I, Chambers GM, Illingworth P, McBain J, Norman RJ. ‘Single embryo transfer reduces the risk of perinatal mortality, a population study’, Hum Reprod. 2012 Sep 17. Misso ML, Costello MF, Garrubba M, Wong J, Hart R, Rombauts L, Melder AM, Norman RJ, Teede HJ. ‘Metformin versus clomiphene citrate for infertility in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis’, Hum Reprod Update. 2012 Sep 6. Misso ML, Teede HJ, Hart R, Wong J, Rombauts L, Melder AM, Norman RJ, Costello MF. ‘Status of clomiphene citrate and metformin for infertility in PCOS’, Trends Endocrinol Metab. 2012 Aug 28. Dunning KR, Watson LN, Sharkey DJ, Brown HM, Norman RJ, Thompson JG, Robker RL, Russell DL. ‘Molecular Filtration Properties of the Mouse Expanded Cumulus Matrix: Controlled Supply of Metabolites and Extracellular Signals to Cumulus Cells and the Oocyte’, Biol Reprod. 2012 Jul 25. Lim SS, Davies MJ, Norman RJ, Moran LJ. ‘Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis’, Hum Reprod Update. 2012 Jul 4. Joham AE, Teede HJ, Norman RJ. ‘Polycystic ovary syndrome: what do the new guidelines recommend?’, Medicine Today 2012; 13(5): 58-63. Yang X, Wu LL, Chura LR, Liang X, Lane M, Norman RJ, Robker RL. ‘Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes’, Fertil Steril. 2012 Jun;97(6):1438-43. Thomson RL, Brinkworth GD, Noakes M, Clifton PM, Norman RJ, Buckley JD. ‘The effect of diet and exercise on markers of endothelial function in overweight and obese women with polycystic ovary syndrome’, Hum Reprod. 2012 May 2. Norman RJ. ‘Does ovulation induction with follicle-stimulating hormone still have a future in polycystic ovary syndrome?’, Fertil Steril. 2012 May 8. Tang T, Lord JM, Norman RJ, Yasmin E, Balen AH. ‘Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility’, Cochrane Database Syst Rev. 2012 May 16;5:CD003053. Smith CA, de Lacey S, Chapman M, Ratcliffe J, Norman RJ, Johnson N, Sacks G, Lyttleton J, Boothroyd C. ‘Acupuncture to improve live birth rates for women undergoing in vitro fertilization: a protocol for a randomized controlled trial’, Trials. 2012 May 18;13(1):60. Costello MF, Misso ML, Wong J, Hart R, Rombauts L, Melder A, Norman RJ, Teede HJ . ‘The treatment of infertility in polycystic ovary syndrome: a brief update’, Aust N Z J Obstet Gynaecol. 2012 May 28. Homan G, Litt J, Norman RJ. ‘The FAST study: Fertility ASsessment and advice Targeting lifestyle choices and behaviours: a pilot study’, Hum Reprod. 2012 May 30. Witchel SF, Recabarren SE, González F, Diamanti-Kandarakis E, Cheang KI, Duleba AJ, Legro RS, Homburg R, Pasquali R, Lobo RA, Zouboulis CC, Kelestimur F, Fruzzetti F, Futterweit W, Norman RJ, Abbott DH. ‘Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome’, Endocrine. 2012 Jun 4. Reid SM, Norman RJ. ‘PCOS and thromboembolism: a complex case’, Endocrinology Today. April 2012. Misso ML, Wong JLA, Teede HJ, Hart R, Rombauts L, Melder AM, Norman RJ, Costello MF. ‘Aromatase inhibitors for PCOS: a systematic review and meta-analysis’, Hum Reprod Update. 2012. Wu LL, Russell DL, Norman RJ, Robker RL. ‘Endoplasmic Reticulum (ER) Stress in Cumulus-Oocyte Complexes Impairs Pentraxin-3 Secretion, Mitochondrial Membrane Potential ({Delta}{Psi}m), and Embryo Development’, Mol Endocrinol. 2012 Mar 1. Boyle JA, Cunningham J, Dunbar T, O’Dea K, Norman RJ. ‘Prevalence of Polycystic Ovary Syndrome in sample of urban Indigenous women in Darwin, Australia’, The Medical Journal of Australia. 2012 Jan 16. Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, Boivin J, Petraglia F, Wijeyeratne CN, Norman RJ et al, ‘Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group’, Fertil Steril. 2012 Jan. Book Chapters 2012 Norman RJ. ‘Manging Failures-Troubleshooting and Patient Counselling’. Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings), Chapter 25, pp 212-215. Refereed Journal Articles 2011 Boyle JA, Cunningham J, Dunbar T, O'Dea K, Norman RJ. ‘A high prevalence of Polycystic Ovary Syndrome in sample of urban Indigenous women in Darwin', The Medical Journal of Australia. In press (accepted 12/10/2011). Norman RJ. ‘The power of one and its cost', The Medical Journal of Australia. In press (accepted 08/10/2011). Janse F, Eijkemans M, Goverde AJ, Lentjes EG, Hoek A, Lambalk CB, Hickey TE, Fauser B & Norman RJ. ‘Assessment of androgen concentrations in women: liquid chromatography - tandem mass spectrometry and extraction radioimmunoassay show comparable results. Eur J Endocrinol. In press (accepted 03/10/11). [Epub ahead of print]. Escobar-Moreale H, Carmina E, Dewailly D, Gambineri A, Kelestimur F, Moghetti P, Pugeat M, Wijeyaratne CN, Witchel S & Norman RJ. ‘Epidemiology, diagnosis and management of hirsutisma: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society', Hum Reprod. In press (accepted 20/9/11). Teede HJ, Misso ML, Deeks AA, Moran LJ, Stuckey BG, Wong JJ, Norman RJ & Costello MF. ‘Assessment and management of polycystic ovary syndrome: summary of an evidence-based guideline'. The Medical Journal of Australia. 2011 September 19; 195(6): s65-s112 Fauser B, Tarlatzis BC, Rebar B, Legro RS, Balen AH, Lobo RA, Carmina E, Chang JR, Yildiz BO, Laven JS, Boivin J, Petraglia F, Wijeyeratne CN, Norman RJ, Dunaif A, Franks S, Wild RA, Dumesic D & Barnhart K. ‘Consensus of women's health aspects of polycystic ovary syndrome (PCOS)', Hum Reprod. In press (accepted 2011) Ngo DT, Chan WP, Rajendran S, Heresztyn T, Amarasekera A, Sverdlov AL, O’Loughlin PD, Morris HA, Chirkov YY, Norman RJ, Horowitz JD. ‘Determinants of insulin responsiveness in young women: Impact of polycystic ovarian syndrome, nitric oxide, and vitamin D’, Nitric Oxide, 30 June 2011 [Epub ahead of print]. Moran LJ, Tsagareli V, Norman RJ, Noakes M. ‘Diet and IVF Approaches (DIVA) pilot study: Short-term weight loss improves pregnancy rates in overweight / obese women undertaking IVF’, Australian and New Zealand Journal of Obstetrics and Gynaecology, in press (accepted 27/5/11). Norman RJ, Zegers-Hochschild F, Salle BS, Elbers J, Heijen E, Marintcheva-Petrova M, Mannaerts B; for the Trust Investigators. ‘Repeated ovarian stimulation with corifollitropin alfa in patients in a GnRH antagonist protocol: no concern for immunogenicity’, Hum Reprod. 2011 May 27. [Epub ahead of print] Dunning KR, Akison LK, Russell DL, Norman RJ, Robker RL. ‘Increased Beta-Oxidation and Improved Oocyte Developmental Competence in Response to L-Carnitine During Ovarian In Vitro Follicle Development in Mice’, Biol Reprod. 2011 May 25. [Epub ahead of print] Hickey M, Doherty DA, Atkinson H, Sloboda DM, Franks S, Norman RJ, Hart R. ‘Clinical, ultrasound and biochemical features of polycystic ovary syndrome in adolescents: implications for diagnosis’, Hum Reprod. 2011 Apr 8. Hart R, Doherty DA, Mori T, Huang RC, Norman RJ, Franks S, Sloboda D, Beilin L, Hickey M. ‘Extent of metabolic risk in adolescent girls with features of polycystic ovary syndrome’, Fertil Steril. 2011 Mar 28. [Epub ahead of print] Moran LJ, Hutchison SK, Norman RJ, Teede HJ. ‘Lifestyle changes in women with polycystic ovary syndrome’, Cochrane Database Syst Rev. 2011 Feb 16;2:CD007506. Community EngagementMedia Reports 2011-2013 2013
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