Biography/ Background
Awards & Achievements
Research Interests
Publications
Professional Associations

Dr Sabrina Heng

Telephone	+61 8 8313 2364
Position	ARC Super Science Fellow
Email	sabrina.heng@adelaide.edu.au
Fax	+61 8 8313 4358
Building	The Braggs
Floor/Room	1 11
Campus	North Terrace
Org Unit	Chemistry (School of Chemistry and Physics)

To link to this page, please use the following URL:
http://www.adelaide.edu.au/directory/sabrina.heng

Biography/ Background

2010 - present Australian Research Council Super Science Fellow

Research Area: Light driven on/off Sensors.

(Institute of Photonics & Advanced Sensing, University of Adelaide)

2009 - 2010 Post Doctoral Fellow with Prof. Andrew Abell & Prof. Tanya Monro

(School of Chemistry and Physics, University of Adelaide, Australia)

2004 - 2009 Ph.D with Prof. Evan Kantrowtiz

Fields: Medicinal Chemistry, Organic Synthesis, Enzymology.

(Boston College, Massachusetts, USA)

Awards & Achievements

2005 Donald White Teaching Excellence Award (Boston College)

Research Interests

Development of novel sensing platforms.

Disease diagnosis using molecular sensors.

Control of enzyme/protein function using photoswitchable molecules.

Publications

RECENT PUBLICATIONS

Nanoliter-scale, regenerable ion sensor: sensing with a surface functionalized microstructured optical fibre.

Sabrina Heng, Mai-Chi Nguyen, Roman Kostecki, Tanya M. Monro and Andrew D. Abell

RSC Advances, 2013, 3, 8308-8317. doi: 10.1039/C3RA40321A

New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds.

Heng S, Tieu W, Hautmann S, Kuan K, Pedersen DS, Pietsch M, Gütschow M, Abell AD.

Bioorg Med Chem. 2011, 19 (24), 7453-63. doi: 10.1016/j.bmc.2011.10.042.

Fluorescence-based aluminum ion sensing using a surface-functionalized microstructured optical fiber.

Warren-Smith SC, Heng S, Ebendorff-Heidepriem H, Abell AD, Monro TM.

Langmuir. 2011, 27 (9), 5680-5. doi: 10.1021/la2002496.

Sensing with suspended-core optical fibers. Enzyme detection by surface plasmon resonance using specially engineered spaces and plasmonic labeling.

Francois, A, Heng S, Kosteki, R, Monro, T.M

Proc. of SPIE, 2010, 8024, 802402. doi: 10.1117/12.883835

Sensing with suspended-core optical fibers.

Monro, TM, Warren-Simth SC, Schartner, EP, Francois, A, Heng S, Ebendorff-Heidepriem H, Afshar V, S.

Optical Fiber Technology, 2010, 16, 343-356. doi: 10.1016/j.yofte.2010.09.010

Designing inhibitors against fructose 1,6-bisphosphatase: exploring natural products for novel inhibitor scaffolds.

Heng S, Harris KM, Kantrowitz ER.

Eur J Med Chem. 2010, 45 (4), 1478-84. doi: 10.1016/j.ejmech.2009.12.055.

A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase.

Heng S, Gryncel KR, Kantrowitz ER.

Bioorg Med Chem. 2009, 17 (11), 3916-22. doi: 10.1016/j.bmc.2009.04.030.

Design, synthesis, and bioactivity of novel inhibitors of E. coli aspartate transcarbamoylase.

Eldo J, Heng S, Kantrowitz ER.

Bioorg Med Chem Lett. 2007, 17 (7), 2086-90.

T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition.

Heng S, Stieglitz KA, Eldo J, Xia J, Cardia JP, Kantrowitz ER.

Biochemistry. 2006, 45 (33), 10062-71.

Professional Associations

2007 - present American Chemical Society

2011 - present Scientist in Schools

Entry last updated: Thursday, 6 Jun 2013

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