Candida parapsilosis

RG-2 organism.

Culture: 
Colonies (SDA) white to cream-coloured smooth, glabrous, yeast-like.

Microscopy: 
Predominantly small, globose to ovoid budding blastoconidia, 3-4 x 5-8 µm, with some larger elongated forms present.

India ink preparation: 
Negative - no capsules present.

Dalmau plate culture: 
Abundant, much-branched pseudohyphae in a delicate tree-like pattern with 2-3 blastoconidia in small clusters at intervals along the pseudohyphae.

Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow, nd No Data
Germ Tube - L-Sorbose +,s L-Arabinose + D-Glucitol +
Fermentation   Sucrose + D-Arabinose - 𝝰-M-D-Glucoside +
Glucose + Maltose + D-Ribose v D-Gluconate -
Galactose + Cellobiose - L-Rhamnose - DL-Lactate -
Sucrose + Trehalose + D-Glucosamime v myo-Inositol -
Maltose -,s Lactose - N-A-D-glucosamine + 2-K-D-Gluconate +
Lactose - Melibiose - Glycerol + D-Glucuronate -
Trehalose -,s Raffinose - Erythritol - Nitrate -
Assimilation   Melezitose + Ribitol v Urease -
Glucose + Soluble Starch - Galactitol - 0.1% Cycloheximide -
Galactose + D-Xylose + D-Mannitol + Growth at 37C +

Key features:
Abundant, much-branched pseudohyphae in a delicate tree-like pattern with 2-3 blastoconidia in small clusters at intervals along the pseudohyphae.

Antifungal susceptibility: Candida parapsilosis (Australian national data); MIC µg/mL.
Antifungal No ≤0.008 0.016 0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 ≥64
AMB 863   2 8 28 132 149 239 231 71 3        
FLU 864         14 76 203 283 165 79 29 6 7 2
ISAV 289 14 16 60 108 70 11 4 4       2    
VORI 784 175 179 220 126 57 20 5 1 1          
POSA 694 4 44 168 333 118 25 2              
ITRA 865 1 15 90 207 430 107 12 3            
ANID 599       3 8 10 48 198 257 53 22      
MICA 599   1   3 1 6 55 224 226 72 11      
CAS 604     1 1 7 46 272 303 64 6 1 3    
5FC 865 2 1 31 222 264 284 49 7 3         2

Go to Candida metapsilosis Go to Candida orthopsilosis  Back to Candida