Medical Research Future Fund (MRFF)

As a “translation fund”, the MRFF will supercharge the growth of Australian health and medical research to better translate research into health outcomes, improve lives, build the economy and contribute to health system sustainability.

View MRFF application instructions

The MRFF is an ongoing research fund set up by the Australian Government in 2015. In July 2020, it grew to $20 billion. The net interest from the fund pays for health and medical research initiatives. 

The Medical Research Future Fund Act 2015 requires the Minister for Health must take into account the Australian Medical Research and Innovation Priorities that are in force when approving MRFF grants.

These are the second set of priorities for the MRFF selected by the Australian Medical Research Advisory Board, and influence the format and direction of both competitive funding rounds and non-competitive investments.

The Department of Health has a useful overview of how the MRFF strategy and each set of priorities have informed the funding programs established so far. There will be opportunity to engage in the national consultations as future MRFF strategies and priorities are set, which will be an important way to represent the fields of research undertaken at the University of Adelaide.

Funding schemes Min Data Internal review Close

Targeted translation research accelerator for diabetes and cardiovascular disease
For for innovative preventative, diagnostic, therapeutic and/or disease management projects or solutions addressing one of the following Priority Areas.

Priority 1: Atherosclerosis, including cerebrovascular disease
Priority 2: Cardiomyopathy and heart failure
Priority 3: Obesity as it relates to diabetes
Priority 4: Mental health as it relates to diabetes
Priority 5: Glucose control in type 1 diabetes (T1D), type 2 diabetes (T2D), double diabetes and/or gestational diabetes mellitus (GDM)

  • Requires co-contribution to the value of at least 50% of funding requested
  • Zoom info session: 12 Oct 2021 (register here)
  • AUD $200k - $750k
  • Further information
n/a 28 Oct 2021 4 Nov 2021

2021 Improving the Health and Wellbeing of Aboriginal and Torres Strait Islander Mothers and Babies Grant Opportunity
For Indigenous-led projects that translate existing knowledge through culturally safe care for pregnancy, birthing and the post-natal period, for example on-country birthing and continuity of family and midwifery care.

n/a 18 Nov 2021 25 Nov 2021

2021 Traumatic Brain Injury Grant Opportunity
Accelerating Australian TBI research to develop and deliver innovative and effective treatments that substantially and equitably improve outcomes for people who experience TBI, in partnership with patients and carers across 2 streams:
Stream 1: $1.5M - $3M for competitively selected national consortium/s to develop more effective, evidence-based care for mild TBI.
Stream 2: $1M for innovative approaches for the prevention, diagnosis and treatment of sports-related concussion.

25 Jan 2022 2 Feb 2022 9 Feb 2022

2021 Chronic Musculoskeletal Conditions in Children and Adolescents Grant Opportunity
To fund research into chronic musculoskeletal conditions occurring in children, across 3 streams:
Stream 1: Chronic autoimmune diseases that affect the musculoskeletal system
Examples include, but are not limited to, juvenile idiopathic arthritis, juvenile systemic lupus erythematosus and juvenile scleroderma. $500k - $2.5M per project.
Stream 2: Chronic musculoskeletal pain
Examples include, but are not limited to, knee pain, lower back pain and neck pain, including complex pain syndromes and recurrent headache (regardless of aetiology). $500k - $2.5M per project.
Stream 3: Congenital musculoskeletal diseases
Examples include, but are not limited to, muscular dystrophy, scoliosis and hip dysplasia. $500k - $2.5M per project.

2 Feb 2022 9 Feb 2022 16 Feb 2022

Dementia, ageing and aged care mission grants
For research that enhances the lives of Australians as they age, across 4 streams:

Stream 1: $10M total. $2M - $5M per project. Implementation research on preventive health care to understand enablers and barriers, and develop tools and strategies for improving access to and utilisation of care.
Stream 2: $11.5M total. ≤ $2M per project. Support early diagnosis and treatment of conditions that are prevalent among older Australians, addressing stigma and including vulnerable populations.

Stream 3: $3M to fund one national consortium to identify the key components of high-quality care for older Australians and how these can be combined to ensure optimal care.
Stream 4: $200k - $1M to fund one early stage, small-scale development project to establish feasible evidence based care approaches using data for older Australians in care.

2 Feb 2022 9 Feb 2022 16 Feb 2022

2021 Genomics Health Futures Mission Grant Opportunity
To fund research to integrate genomics knowledge and technology into clinical practice, across 6 streams:
Stream 1: $20M total, ≤ $3M per project. Develop disease-agnostic, high throughput and scalable functional genomics platforms to increase the diagnostic rate of unresolved cases and accelerate the development of experimental therapeutics.
Stream 2: $12M total, ≤ $3M per project. Develop new models of genomic newborn screening.
Stream 3: $5M to fund one national consortium to conduct research addressing emerging ethical, legal and social issues associated with the governance of clinical and genomic datasets.
Stream 4: $5M to fund one national consortium to conduct research to develop effective approaches for responsible, culturally appropriate and nationally consistent involvement of Aboriginal and/or Torres Strait Islander people in genomics research and clinical practice.
Stream 5: $10M to fund one national consortium to conduct research to enrich genomics databases to support the inclusion of culturally and linguistically diverse groups in genomics research, and equitable benefit from genomics in health.
Stream 6: $4M total. $200k - $1M per project. Conduct small-scale development projects to establish feasible evidence-based approaches for population cohort research, focusing on culturally and linguistically diverse groups, including:

  • Using the international landscape to inform an Australian approach
  • Identifying potential cohorts for analysis and integration
  • Identifying opportunities for Australian leadership and contribution.


2 Feb 2022 9 Feb 2022 16 Feb 2022

International clinical trial collaborations grants - round 2
Supports Australian research teams in conducting clinical trial research in collaboration with international counterparts.

2 Feb 2022 9 Feb 2022 16 Feb 2022
Cardiovascular Health Grant Opportunity

To advance cardiovascular health, across 5 streams:
Stream 1: $8M total. ≤$1M per project. Improve understanding of cardiovascular disease risk, including biological mechanisms.
Stream 2: $6M total. ≤$1M per project. Support effective adoption and adherence of preventive health interventions for cardiovascular disease and stroke.
Stream 3: $8M total. ≤ $1M per project. Accelerate equitable patient access to best care that results in best possible outcomes.
Stream 4: $6M total. $200k - $1M per project. Small-scale development projects that will establish feasible, evidence-based approaches for identifying and targeting personalised lifelong care approaches, to prevent further stroke or heart events.
Stream 5: $6M total. $200k - $1M per project. Small-scale development projects that establish feasible, evidence-based approaches for developing new treatments for recovery with better understanding of the biology of recovery, leading to improved monitoring and new treatments.

Proposals must focus on one of the Topics identified under each stream - refer to the guidelines for further details.

9 Feb 2022 16 Feb 2022 23 Feb 2022

2021 Primary Health Care Research Grant Opportunity
Supports research into emerging fields of wearable health technologies and point-of-care testing. Outcomes must inform clinical care and better target public health interventions.
Stream 1: test and implement new applications of existing wearables in primary health care practice, with potential for scalability
Stream 2: test the effectiveness of new point-of-care testing delivery models:

  • in rural, regional and/or remote areas (MM3-7 according to the Modified Monash Model locator3) and/or
  • through mobile delivery.

Applicants must demonstrate a clear pathway for any regulatory approvals their technology may need, such as undergoing conformity assessment, or inclusion in the Australian Register of Therapeutic Goods (ARTG).

9 Feb 2022 16 Feb 2022 23 Feb 2022

2021 Stem Cell Therapies Grant Opportunity
To support stem cell research to deliver innovative, safe and effective treatments, across 2 streams:

Stream 1 (Accelerator): Up to $7M per project. Developing novel stem cell-based therapies that have the potential to transform clinical care.

Stream 2 (Accelerator): Up to $5M per project. Evaluating and performing pre-clinical screening of new therapeutics using human tissues made from stem cells.

9 Feb 2022 16 Feb 2022 23 Feb 2022

GBM AGILE Grant Opportunity (Australian Brain Cancer Mission)
To lead, co-ordinate and manage the implementation and evaluation of the Australian arm of the Glioblastoma Adaptive Global Innovative Learning Environment (GBM AGILE) clinical trial.

16 Feb 2022 23 Feb 2022 2 March 2022

Ministerial announcements will frequently precede eventual funding rounds by weeks or months. Wherever possible, such advance alerts will be outlined below

While MRFF processes are distinct to NHMRC or ARC, and peer review does not obligatorily guide Ministerial funding decisions, some MRFF rounds do utilise peer review processes, managed online by either the NHMRC (Sapphire) or the Department of Industry, Innovation & Science (Business Portal).

Get involved

For schemes that do undertake peer review of grant applications, University of Adelaide involvement is critical.

The NHMRC invite you to self-nominate to assist in MRFF grant review and assessment processes as a member of a Grant Assessment Committee for a number of 2020-21 MRFF grant opportunities. It is necessary to register for these MRFF panels as they are coordinated independent of NHMRC peer review activities. Register here.

Anyone who has volunteered and participated in MRFF Peer Review is urged to contact MRFF Strategic Research Team, for University acknowledgement and support.

It is the intention of the Taskforce to:

  • Capture critical knowledge and information
  • Share the information with groups/individuals who need to know
  • Understand the needs of researchers, to help our University better support MRFF applications and activity

Talk to your representative, or contact the MRFF Strategic Research Team for more information.



A/Prof Mathias Baumert

Theme Leader – Medical, Health and Bioprocessing Technologies, ECMS

A/Prof Michael Beard

School of Biological Sciences Research Committee chair, and
representative for the Research Centre for Infectious Diseases

Prof Alex Brown

Theme Leader, Aboriginal Health Equity, SAHMRI and Adelaide Medical School

A/Prof Gustavo Carneiro

Professor of Computer Science

Prof Józef Gecz

Adelaide Medical School Research Committee chair

Prof Bronwyn Gillanders

DDR Faculty of Sciences – also represent human health-related Animal and
Veterinary Sciences, Agriculture Food and Wine and Physical Sciences

Prof Tim Hughes

Precision Medicine Theme Leader at SAHMRI; Cancer Council Chair in
Cancer Research and Consultant Haematologist at the Royal Adelaide Hospital.

Prof Mark Hutchinson

Director of the Centre for Nanoscale BioPhotonics

Prof Mark Jenkinson

Professor of Neuroimaging at the University of Adelaide, SAHMRI,
Australian Institute for Machine Learning (AIML), and the University of Oxford

Prof John Lynch

Interim DDR Faculty of Health & Medical Sciences
School of Public Health

A/Prof Anna Ma-Wyatt

School of Psychology Research Committee chair

A/Prof Peter Psaltis

Cardiologist with Central Adelaide Local Health Network (CALHN);
Deputy Leader of the Heart Health Theme and Co-director of the
Vascular Research Centre at SAHMRI.

Prof. Sarah Robertson

Senior Research Fellow

Dr. Nick Smith

Paediatric Neurologist at the Women’s and Children’s Hospital

Mr Steve Whetton

Deputy Director - South Australian Centre for Economic Studies,
representing Health Economics

Dr Peter Zilm

Adelaide Dental School Research Committee chair

Need help?

For further information please contact our MRFF Strategic Research Team.