Medical Research Future Fund (MRFF)

Targeted translation research accelerator for diabetes and cardiovascular disease
For for innovative preventative, diagnostic, therapeutic and/or disease management projects or solutions addressing one of the following Priority Areas.

Priority 1: Atherosclerosis, including cerebrovascular disease
Priority 2: Cardiomyopathy and heart failure
Priority 3: Obesity as it relates to diabetes
Priority 4: Mental health as it relates to diabetes
Priority 5: Glucose control in type 1 diabetes (T1D), type 2 diabetes (T2D), double diabetes and/or gestational diabetes mellitus (GDM)

• Requires co-contribution to the value of at least 50% of funding requested
• Zoom info session: 12 Oct 2021 (register here)
• AUD $200k - $750k
• Further information

2021 Improving the Health and Wellbeing of Aboriginal and Torres Strait Islander Mothers and Babies Grant Opportunity
For Indigenous-led projects that translate existing knowledge through culturally safe care for pregnancy, birthing and the post-natal period, for example on-country birthing and continuity of family and midwifery care.

• Opens 12 Aug 2021
• Total budget of AUD $15M
• Further information

2021 Traumatic Brain Injury Grant Opportunity
Accelerating Australian TBI research to develop and deliver innovative and effective treatments that substantially and equitably improve outcomes for people who experience TBI, in partnership with patients and carers across 2 streams:
Stream 1: $1.5M - $3M for competitively selected national consortium/s to develop more effective, evidence-based care for mild TBI.
Stream 2: $1M for innovative approaches for the prevention, diagnosis and treatment of sports-related concussion.

• Further information       

2021 Chronic Musculoskeletal Conditions in Children and Adolescents Grant Opportunity
To fund research into chronic musculoskeletal conditions occurring in children, across 3 streams:
Stream 1: Chronic autoimmune diseases that affect the musculoskeletal system
Examples include, but are not limited to, juvenile idiopathic arthritis, juvenile systemic lupus erythematosus and juvenile scleroderma. $500k - $2.5M per project.
Stream 2: Chronic musculoskeletal pain
Examples include, but are not limited to, knee pain, lower back pain and neck pain, including complex pain syndromes and recurrent headache (regardless of aetiology). $500k - $2.5M per project.
Stream 3: Congenital musculoskeletal diseases
Examples include, but are not limited to, muscular dystrophy, scoliosis and hip dysplasia. $500k - $2.5M per project.

• Total budget of AUD $20M
• Further information

Dementia, ageing and aged care mission grants
For research that enhances the lives of Australians as they age, across 4 streams:

Stream 1: $10M total. $2M - $5M per project. Implementation research on preventive health care to understand enablers and barriers, and develop tools and strategies for improving access to and utilisation of care.
Stream 2: $11.5M total. ≤ $2M per project. Support early diagnosis and treatment of conditions that are prevalent among older Australians, addressing stigma and including vulnerable populations.
Stream 3: $3M to fund one national consortium to identify the key components of high-quality care for older Australians and how these can be combined to ensure optimal care.
Stream 4: $200k - $1M to fund one early stage, small-scale development project to establish feasible evidence based care approaches using data for older Australians in care.

• Total budget of AUD $ 25.5M
• Further information

2021 Genomics Health Futures Mission Grant Opportunity
To fund research to integrate genomics knowledge and technology into clinical practice, across 6 streams:
Stream 1: $20M total, ≤ $3M per project. Develop disease-agnostic, high throughput and scalable functional genomics platforms to increase the diagnostic rate of unresolved cases and accelerate the development of experimental therapeutics.
Stream 2: $12M total, ≤ $3M per project. Develop new models of genomic newborn screening.
Stream 3: $5M to fund one national consortium to conduct research addressing emerging ethical, legal and social issues associated with the governance of clinical and genomic datasets.
Stream 4: $5M to fund one national consortium to conduct research to develop effective approaches for responsible, culturally appropriate and nationally consistent involvement of Aboriginal and/or Torres Strait Islander people in genomics research and clinical practice.
Stream 5: $10M to fund one national consortium to conduct research to enrich genomics databases to support the inclusion of culturally and linguistically diverse groups in genomics research, and equitable benefit from genomics in health.
Stream 6: $4M total. $200k - $1M per project. Conduct small-scale development projects to establish feasible evidence-based approaches for population cohort research, focusing on culturally and linguistically diverse groups, including:

• Using the international landscape to inform an Australian approach
• Identifying potential cohorts for analysis and integration
• Identifying opportunities for Australian leadership and contribution.

• Total budget of AUD $56M 
• Further information

International clinical trial collaborations grants - round 2
Supports Australian research teams in conducting clinical trial research in collaboration with international counterparts.

• Total budget of AUD $6.3M
• Further information

To advance cardiovascular health, across 5 streams:
Stream 1: $8M total. ≤$1M per project. Improve understanding of cardiovascular disease risk, including biological mechanisms.
Stream 2: $6M total. ≤$1M per project. Support effective adoption and adherence of preventive health interventions for cardiovascular disease and stroke.
Stream 3: $8M total. ≤ $1M per project. Accelerate equitable patient access to best care that results in best possible outcomes.
Stream 4: $6M total. $200k - $1M per project. Small-scale development projects that will establish feasible, evidence-based approaches for identifying and targeting personalised lifelong care approaches, to prevent further stroke or heart events.
Stream 5: $6M total. $200k - $1M per project. Small-scale development projects that establish feasible, evidence-based approaches for developing new treatments for recovery with better understanding of the biology of recovery, leading to improved monitoring and new treatments.

Proposals must focus on one of the Topics identified under each stream - refer to the guidelines for further details.

• Total budget of AUD $ 34M
• Further information

2021 Primary Health Care Research Grant Opportunity
Supports research into emerging fields of wearable health technologies and point-of-care testing. Outcomes must inform clinical care and better target public health interventions.
Stream 1: test and implement new applications of existing wearables in primary health care practice, with potential for scalability
Stream 2: test the effectiveness of new point-of-care testing delivery models:

• in rural, regional and/or remote areas (MM3-7 according to the Modified Monash Model locator3) and/or
• through mobile delivery.

Applicants must demonstrate a clear pathway for any regulatory approvals their technology may need, such as undergoing conformity assessment, or inclusion in the Australian Register of Therapeutic Goods (ARTG).

• Further information

2021 Stem Cell Therapies Grant Opportunity
To support stem cell research to deliver innovative, safe and effective treatments, across 2 streams:

Stream 1 (Accelerator): Up to $7M per project. Developing novel stem cell-based therapies that have the potential to transform clinical care.

Stream 2 (Accelerator): Up to $5M per project. Evaluating and performing pre-clinical screening of new therapeutics using human tissues made from stem cells.

• Total budget of AUD $25M
• Further information

GBM AGILE Grant Opportunity (Australian Brain Cancer Mission)
To lead, co-ordinate and manage the implementation and evaluation of the Australian arm of the Glioblastoma Adaptive Global Innovative Learning Environment (GBM AGILE) clinical trial.

• AUD $12M
• Further information