PUB HLTH 7111 - Industrial Toxicology
North Terrace Campus - Semester 2 - 2016
General Course Information
Course Code PUB HLTH 7111 Course Industrial Toxicology Coordinating Unit Public Health Term Semester 2 Level Postgraduate Coursework Location/s North Terrace Campus Units 3 Contact 1 week full time intensive Available for Study Abroad and Exchange N Course Description This course reviews concepts in chemical toxicology which constitute a rational basis for the setting of chemical exposure standards. It includes an overview of the principles of toxicology; biological processes such as toxicant absorption, distribution, metabolism and excretion; the use of toxicity tests and other data to characterise a chemical's toxic effects with specific emphasis on carcinogenicity, mutagenicity, neurotoxicity and developmental toxicity; and the problem of estimating risk.
Course Coordinator: Dr Paul Rothmore
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
1 Describe toxicology as a discipline in the overall health sciences framework. 2 Explain the basic concepts of chemical hazard and exposure as determinants of chemical toxicity. Describe key pathways and mechanisms of chemical absorption, distribution, metabolism, storage and excretion in the human body. 3 Explain dose-response relationships as the basis of toxicity. 4 Outline the derivation of Reference Dose (RfD) and other related measures of occupational exposure. 5 Describe the scientific basis of occupational exposure assessments and practical methods for their determination. 6 Critically interpret Chemical Safety Data Sheets (SDS) and discuss issues of relevance to the workplace setting. 7 Gather and critically interpret toxicological information from diverse resources for human health hazard and risk assessment.
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Deep discipline knowledge
- informed and infused by cutting edge research, scaffolded throughout their program of studies
- acquired from personal interaction with research active educators, from year 1
- accredited or validated against national or international standards (for relevant programs)
1-5 Critical thinking and problem solving
- steeped in research methods and rigor
- based on empirical evidence and the scientific approach to knowledge development
- demonstrated through appropriate and relevant assessment
6, 7 Teamwork and communication skills
- developed from, with, and via the SGDE
- honed through assessment and practice throughout the program of studies
- encouraged and valued in all aspects of learning
1-5 Career and leadership readiness
- technology savvy
- professional and, where relevant, fully accredited
- forward thinking and well informed
- tested and validated by work based experiences
N/A Intercultural and ethical competency
- adept at operating in other cultures
- comfortable with different nationalities and social contexts
- Able to determine and contribute to desirable social outcomes
- demonstrated by study abroad or with an understanding of indigenous knowledges
N/A Self-awareness and emotional intelligence
- a capacity for self-reflection and a willingness to engage in self-appraisal
- open to objective and constructive feedback from supervisors and peers
- able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate
Required ResourcesThere is no specific required textbook for this course. Notes and additional readings will be made available.
The following reference will be useful.
Department of Health and Aging, enHealth Council (2012) Environmental Health Risk Assessment – Guidelines for Assessing Human Health Risks from Environmental Hazards (Commonwealth of Australia, Canberra)
It is recommended that students download for this document directly from:
Recommended ResourcesSee MyUni
Online LearningPre-reading will be made available online. Formative quizzes will be prescribed from existing (freely available) internet sources, e.g. US National Library of Medicine (http://sis.nlm.nih.gov/enviro/toxtutor.html)
Learning & Teaching Activities
Learning & Teaching ModesThis course revolves around a series of workshops and seminars, involving critical reflection and discussion. Toxicological concepts will be contextualised via case studies and expert panel discussions.
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.1 week full time intensive.
Learning Activities SummaryIntroduction to Toxicology (Q/A, critiques, group exercises)
Introduction and Basic Principles
Exposure & Toxicokinetics
Factors influencing occupational exposures.
Toxicity & toxicogenomics
Methods & Techniques (exposure, biomonitoring)
Chemical Groupings and workplace scenarios (critiques, group exercises)
Toxicology of prominent chemical groupings (solvents, metals etc.)
Chemical exposure standards
Information available in the workplace (critiques, group exercises, expert panel)
Safety data sheets – critical examination
Expert panel discussion
Topical issues and emerging issues (seminar and class discussions)
Selected chemicals and exposure scenarios
Stakeholder communication, legal issues
Specific Course RequirementsNone.
Small Group Discovery ExperienceN/A
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Task Assessment Type Weighting Learning course objective(s) being addressed Class Participation Summative 10% 1-7 Assignment Summative 40% 6, 7 Exam Summative 50% 1-5
Assessment Related RequirementsNone.
Assessment DetailStudent participation: Marks will be based on the contribution of each student to class discussions and individual/group exercises
Written examination: This will be approximately 1.5 hr duration, held at the end of the intensive face to face component. Questions will be 50% multiple choice style and 50% written, short essay-type, answer.
Major assignment: 2500 words, based on a chemical used in Australian industry. The assignment will address exposure scenario, potential health effects, risk management with recommendations based on critical review of the literature.
All extensions for assignments must be requested, at the latest, by the last working day before the due date of submission. Extensions will generally be granted only on medical or genuine compassionate grounds. Supporting documentation must be provided at the time a student requests an extension. Without documentation, extensions will not be granted. Late requests for extension will neither be accepted nor acknowledged.
Only the Course Co-ordinator(s) may grant extensions.
Supporting documentation will be required when requesting an extension. Examples of documents that are acceptable include: a medical certificate that specifies dates of incapacity, a police report (in the case of lost computers, car & household theft etc.), a letter from a Student Counsellor, Education and Welfare Officer (EWO) or Disability Liaison Officer that provides an assessment of compassionate circumstances, or a letter from an independent external counsellor or appropriate professional able to verify the student’s situation. The length of any extension granted will take into account the period and severity of any incapacity or impact on the student. Extensions of more than 10 days will not be granted except in exceptional circumstances.
Marks will be deducted when assignments for which no extension has been granted are handed in late.
All assignments, including those handed in late, will be assessed on their merits. In the case of late assignments where no extension has been granted, 5 percentage points of the total marks possible per day will be deducted. If an assignment that is 2 days late is awarded 65% on its merits, the mark will then be reduced by 10% (5% per day for 2 days) to 55%. If that same assignment is 4 days late, the mark will be reduced by 20% (5% per day for 4 days) to 45%, and so on.
The School of Public Health reserves the right to refuse to accept an assignment that is more than 7 days late.
Assignments submitted after the due date may not be graded in time to be returned on the listed return dates.
Students submitting examinable written work who request (and receive) an extension that takes them beyond the examination period are advised that there is no guarantee that their grades will be processed in time to meet usual University deadlines.
If a student is dissatisfied with an assessment grade they should follow the Student Grievance Resolution Process <https://www.adelaide.edu.au/student/grievance/process/>. Students who are not satisfied with a particular assessment result should raise their concerns with Course Co-ordinator(s) in the first instance. This must be done within 10 business days of the date of notification of the result. Resubmission of any assignment is subject to the agreement of the Course Co-ordinator(s) and will only be permitted for the most compelling of reasons.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
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