CHEM 3214 - Medicinal and Biological Chemistry III
North Terrace Campus - Semester 2 - 2022
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General Course Information
Course Details
Course Code CHEM 3214 Course Medicinal and Biological Chemistry III Coordinating Unit School of Physical Sciences Term Semester 2 Level Undergraduate Location/s North Terrace Campus Units 3 Contact Up to 9 hours per week Available for Study Abroad and Exchange Y Prerequisites CHEM 2545 or equivalent Assumed Knowledge CHEM 3620, CHEM 2540 Assessment Exam, practical work, assignments Course Staff
Course Coordinator: Associate Professor David Huang
Course Timetable
The full timetable of all activities for this course can be accessed from Course Planner.
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Learning Outcomes
Course Learning Outcomes
On successful completion of this course, students will be able to:
1 apply knowledge of synthetic bioorganic chemistry and the mechanisms for biological activity and key biological reactions to design bioactive compounds. 2 describe and explain the theory and role of electron transfer in biological systems. 3 explain the role of medicinal and biological chemistry in the pharmaceutical industry. 4 demonstrate proficiency in undertaking individual and/or team-based laboratory investigations using appropriate apparatus and safe laboratory practices, including the collection, analysis, interpretation and communication of results of an experiment. 5 design and plan an investigation by selecting and applying appropriate practical and/or theoretical techniques or tools.
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Attribute 1: Deep discipline knowledge and intellectual breadth
Graduates have comprehensive knowledge and understanding of their subject area, the ability to engage with different traditions of thought, and the ability to apply their knowledge in practice including in multi-disciplinary or multi-professional contexts.
1-5 Attribute 2: Creative and critical thinking, and problem solving
Graduates are effective problems-solvers, able to apply critical, creative and evidence-based thinking to conceive innovative responses to future challenges.
1-3,5 Attribute 3: Teamwork and communication skills
Graduates convey ideas and information effectively to a range of audiences for a variety of purposes and contribute in a positive and collaborative manner to achieving common goals.
4,5 Attribute 4: Professionalism and leadership readiness
Graduates engage in professional behaviour and have the potential to be entrepreneurial and take leadership roles in their chosen occupations or careers and communities.
1-5 Attribute 5: Intercultural and ethical competency
Graduates are responsible and effective global citizens whose personal values and practices are consistent with their roles as responsible members of society.
4,5 Attribute 8: Self-awareness and emotional intelligence
Graduates are self-aware and reflective; they are flexible and resilient and have the capacity to accept and give constructive feedback; they act with integrity and take responsibility for their actions.
4,5 -
Learning Resources
Required Resources
There is no prescribed text for this course. All required course material will be provided by the course instructor(s).
Recommended Resources
Textbooks
- Clayden, Greeves, and Warren, Organic Chemistry (Oxford University Press)
- Weller, Overton, Rourke and Armstrong, Inorganic Chemistry (Oxford University Press)
- Housecroft and Sharpe, Inorganic Chemistry (Pearson)
- Kaim, Schwederski and Klein, Bioinorganic Chemistry - Inorganic Elements in the Chemistry of Life (Wiley)
- Silverstein, Webster, Kiemle, and Bryce, Spectroscopic Identification of Organic Compounds (Wiley)
Online Learning
Teaching materials and course documentation will be posted on the MyUni website (http://myuni.adelaide.edu.au/).
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Learning & Teaching Activities
Learning & Teaching Modes
This course consists of the following components:
- Lectures/Tutorials: 12 x 3 hours per week (timetabled as "Workshops")
- Practicals: 10 x 5.5-hour sessions with one session per week
Workload
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.
A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities Summary
Coursework
Course material will cover the following topics:- Bioorganic Chemistry
- Bioinorganic Chemistry
- Medicinal Chemistry
Practical exercises will provide students with "hands on" experience in the design and conduct of contemporary organic chemistry experiments. These skills-based sessions will allow students to develop their control of chemical reactivity, synthesise and isolate molecular targets, and characterise the structure and properties, all in a safe manner. Training and direction on communicating the results of these investigations in various formats will be provided.
Tutorials
Tutorial sessions will be held weekly and will provide the student with the opportunity to discuss material from the lecture course. Formative tutorial questions will be used to reinforce the concepts introduced in lectures through a combination of qualitative and quantitative problem solving.Specific Course Requirements
Attendance is compulsory at all scheduled chemistry practical sessions. The learning outcomes for this course are substantially dependent on laboratory experience and practice. Therefore, missing any practical class in a semester will result in a grade of FAIL being recorded for the course. Students with medical or compassionate reasons for non-attendance will be given an opportunity to make up missed practical sessions. -
Assessment
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Summary
Assessment task Type of assessment Percentage of total assessment for grading purposes Hurdle (Yes/No) Outcomes being assessed Approx timing of assessment Summative Assignments Formative & Summative 10% No 1-3 Weeks 5,9,13 Practical Formative & Summative 30% No 1-5 Bi-weekly, major reports due every 3 weeks Examination Summative 60% Yes (45%) 1-3 Exam period Assessment Related Requirements
Assessment Item % needed to meet course requirement Additional Assessment Examination 45% Yes - RAA Exam;
a grade of at least 45% must obtainedPractical work is compulsory Satisfactory completion of all practicals, including attendance of ALL practical sessions and reasonable attempt at ALL practical reports Missed practicals can be made up Assessment Detail
Summative Assignments (10% of final course grade)
Students will complete assignments on the course material. There will be 3 assignments on the topics each worth 3.33%. The topics are Bioorganic Chemistry, Bioinorganic Chemistry, and Medicinal Chemistry. Each assignment will consist of a series of short-answer and/or multiple-choice questions.
Practicals (30% of final course grade)
This will come from assessment of experiment reports (3 major reports and 2 minor reports) and in-lab assessments. Each major report is worth 6% of the assessment, each minor report is worth 3% of the assessment, and each in-lab assessment is worth 2% of the assessment. Students will be provided with sample reports, rubrics with assessment criteria, and guidelines on report structure and approximate length. Students will complete 5 experiments, with each experiment taking approximately 2 lab sessions (1 experiment approximately every 2 weeks). They will submit a minor report on the day of completion of an experiment for 2 of the 5 experiments and they will complete an in-lab assessment and submit a major report approximately one week after the completion of an experiment for the other 3 experiments. The in-lab assessment will assess risk assessment, experimental write-up, successful synthesis, and laboratory skills.
Examination (60% of final course grade)
The end-of-semester examination will be based primarily on lecture/tutorial material and will consist of a series of short-answer and/or multiple-choice questions.
Submission
Submission of Assigned Work
Coversheets must be completed and attached to all submitted work. Coversheets can be obtained from the School Office (room G33 Physics) or from MyUNI. Work should be submitted via the assignment drop box at the School Office or via MyUni as instructed.
Extensions for Assessment Tasks
Extensions of deadlines for assessment tasks may be allowed for reasonable causes. Such situations would include compassionate and medical grounds of the severity that would justify the awarding of a supplementary examination. Evidence for the grounds must be provided when an extension is requested. Students are required to apply for an extension to the Course Coordinator before the assessment task is due. Extensions will not be provided on the grounds of poor prioritising of time. The assessment extension application form can be obtained from: https://sciences.adelaide.edu.au/study/student-support/forms-and-policies#academic-forms
Late Submission of Assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.Course Grading
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
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Student Feedback
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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Student Support
- Academic Integrity for Students
- Academic Support with Maths
- Academic Support with writing and study skills
- Careers Services
- International Student Support
- Library Services for Students
- LinkedIn Learning
- Student Life Counselling Support - Personal counselling for issues affecting study
- Students with a Disability - Alternative academic arrangements
- YouX Student Care - Advocacy, confidential counselling, welfare support and advice
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Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
- Academic Credit Arrangements Policy
- Academic Integrity Policy
- Academic Progress by Coursework Students Policy
- Assessment for Coursework Programs Policy
- Copyright Compliance Policy
- Coursework Academic Programs Policy
- Elder Conservatorium of Music Noise Management Plan
- Intellectual Property Policy
- IT Acceptable Use and Security Policy
- Modified Arrangements for Coursework Assessment Policy
- Reasonable Adjustments to Learning, Teaching & Assessment for Students with a Disability Policy
- Student Experience of Learning and Teaching Policy
- Student Grievance Resolution Process
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Fraud Awareness
Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student’s disciplinary procedures.
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