GENETICS 3210 - Advanced Molecular Biology IIIB (Genetics)
North Terrace Campus - Semester 2 - 2014
General Course Information
Course Code GENETICS 3210 Course Advanced Molecular Biology IIIB (Genetics) Coordinating Unit School of Molecular and Biomedical Sci(Inactive) Term Semester 2 Level Undergraduate Location/s North Terrace Campus Units 6 Contact Up to 19 hours per fortnight Prerequisites BIOCHEM 2510 or BIOCHEM 2102 & BIOCHEM 2520 or BIOCHEM 2202 & GENETICS 2510 or GENETICS 2102 & GENETICS 2520 or GENETICS 2202 Incompatible BIOCHEM 3225 & GENETICS 3006 Assumed Knowledge GENETICS 3110 Restrictions Available to BSc(MolBiol) students only Course Description This course combines lectures from GENETICS 3211 Gene Expression and Human & Development Genetics with practical exercises and/or laboratory placements in professional research laboratories. It includes a special set of tutorial/Problem Based Learning (PBL) exercises, not offered in any other course, which are designed to provide students with a perspective of how cutting edge molecular biology principles and techniques are applied to major research questions. The PBL segment of course will include aspects of biochemistry, genetics, microbiology/immunology and chemistry. This course will illustrate that cross-disciplinary approaches are essential in modern research.
Course Coordinator: Associate Professor Michael Lardelli
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
The course aims to give students a level of understanding of concepts and experimental techniques in the areas of gene regulation, developmental genetics and human genetics that would enable them to develop competencies expected of a university graduate in Genetics. The course cannot hope to cover comprehensively the very broad range of research questions in these areas but it will give students understanding of specific exemplary questions and provide them with knowledge of how they can extend their learning as required by future studies and employment. The practical aspect of the course aims to equip students with sufficient fundamental skills to apply them to a broad range of positions requiring these skills. The Problem Based Learning (PBL) exercises aim to give students a perspective of how cutting edge molecular biology principles and techniques are applied to major research questions.
The anticipated knowledge, skills and/or attitude to be developed by the student are:
1 Understanding of the underlying conceptual framework regarding the regulation of genes and how research expands our knowledge in this area 2 Understanding of the underlying conceptual framework regarding how genes control embryo development and how research expands our knowledge in this area 3 Understanding of the underlying conceptual framework regarding human genetics and how research expands our knowledge in this area 4 Comprehension of scientific research data described in peer-reviewed journals 5 Recording of laboratory research notes and analysis and reporting of experimental data 6 The ability to extract relevant information from literature databases and to present it in written form 7 To provide students with the opportunity to derive and interpret novel experimental outcomes in a supportive environment commensurate with their capabilities as a final year candidates for the Degree of Bachelor of Science (Molecular Biology).
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Knowledge and understanding of the content and techniques of a chosen discipline at advanced levels that are internationally recognised. 1,2,3,4,5,6,7 The ability to locate, analyse, evaluate and synthesise information from a wide variety of sources in a planned and timely manner. 4,5,6 An ability to apply effective, creative and innovative solutions, both independently and cooperatively, to current and future problems. 5,6,7 A proficiency in the appropriate use of contemporary technologies. 5 A commitment to continuous learning and the capacity to maintain intellectual curiosity throughout life. 4,6,7 A commitment to the highest standards of professional endeavour and the ability to take a leadership role in the community. 4,6
This course will require the following texts and other resources:
· Text for Human Genetics lectures: 'Human Molecular Genetics - 4th Edition' by Strachan and Read.
· Copies of scientific papers for Gene Regulation and Developmental Genetics aspects of the course (supplied by the lecturers)
· Collaborating research laboratories
· Scientific equipment
· Lecture theatres and tutorial rooms
· Access to University Library
· Access to computers and internet
· Students must supply laboratory coat and safety glasses for their own use
Learning & Teaching Activities
Learning & Teaching Modes
This course will be delivered by the following means:
3 lectures of 1 hour each per week
1 tutorial of 1 hour per fortnight
12 hours of practical laboratory/placement per fortnight (weeks 1-6)
(Note: Students who do not obtain a laboratory placement will perform the normal Practical course of Genetics 3211 in weeks 1-6)
6 PBL sessions of up to 5 hours per week in weeks 7-12.
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.A student enrolled in a 6 unit course, such as this, should expect to spend, on average 24 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities Summary
Week 1 Type of learning activity Topic Lecture Developmental Neurogenetics Practical Laboratory Placement Tutorial or other activity None Week 2 Lecture Developmental Neurogenetics Practical Laboratory Placement Tutorial or other activity Developmental Neurogenetics Week 3 Lecture DeveDevelopmental Neurogenetics / Regulation of Gene Expression Practical Laboratory Placement Tutorial or other activity None Week 4 Lecture Regulation of Gene Expression Practical Laboratory Placement Tutorial or other activity Developmental Neurogenetics Week 5 Lecture Regulation of Gene Expression Practical Laboratory Placement Tutorial or other activity Regulation of Gene Expression Week 6 Lecture Regulation of Gene Expression Practical Laboratory Placement Tutorial or other activity None Week 7 Lecture Plant Developmental Genetics Practical Problem Based Learning Exercises Tutorial or other activity Regulation of Gene Expression Week 8 Lecture Epigenetics Practical Problem Based Learning Exercises Tutorial or other activity Plant Developmental Genetics Mid Semester Break Week 9 Lecture Epigenetics / Human Genetics Practical Problem Based Learning Exercises Tutorial or other activity Epigenetics Week 10 Lecture Human Genetics Practical Problem Based Learning Exercises Tutorial or other activity Human Genetics Week 11 Lecture Human Genetics Practical Problem Based Learning Exercises Tutorial or other activity None Week 12 Lecture Human Genetics Practical Problem Based Learning Exercises Tutorial or other activity Human Genetics Week 13* Lecture Practical Tutorial
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment task Type of assessment Percentage of total assessment for grading purposes # Hurdle
Yes or No #
Outcomes being assessed / achieved Final Examination Summative 60% No 1, 2, 3, 4 Laboratory Placement/Practical Formative/Summative 20% No 1,3,4,7 PBL Summative 20% No 2, 4, 5
Assessment DetailLaboratory Placement (20% of total course grade, learning objectives 1,3,4,7) - comprised of one 10-15 minute oral presentation (4%), laboratory performance (6%) and written practical report (10%) in weeks 1-6. Marked Practical Reports will be handed in at the end of week 6 and promptly assessed by mentors/demonstrators to provide feedback to students and a sense of progressive accomplishment in the course. Students who do not obtain a laboratory placement will perform the normal Practical course of Genetics 3211 for weeks 1-6 and will be assessed as for that course.
PBL exercises, including assessment via 2 small group oral presentations, weeks 7-12: (20% of total course grade, learning objectives 2,4,5). Each individual in the PBL group marked separately.
Final examination (60% of course grade, learning objectives 1,2,3,4). This will be a three hour examination assessing any/all theoretical aspects of the course. The examination includes compulsory areas but also a limited choice of questions within each compulsory area.
SubmissionDetails on submission are provided in the Course Handbook and/or Practical manuals etc.
Late submission of assessments:
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
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