GENETICS 3111 - Genes, Genomes and Molecular Evolution III
North Terrace Campus - Semester 1 - 2021
General Course Information
Course Code GENETICS 3111 Course Genes, Genomes and Molecular Evolution III Coordinating Unit School of Biological Sciences Term Semester 1 Level Undergraduate Location/s North Terrace Campus Units 6 Contact Up to 19 hours per fortnight Available for Study Abroad and Exchange Y Prerequisites GENETICS 2510 & GENETICS 2520 or equivalent Incompatible GENETICS 3110 Course Description The DNA molecules that comprise the informational basis of inheritance in living organisms are collectively referred to as the genome. In this course the organisation, origin and mechanisms of change of prokaryotic and eukaryotic genomes are explored using cytogenetic and molecular genetic analyses. Topics include - structure and function of genomes and chromosomes; chromosomes in disease; the roles of natural selection and chance as drivers of molecular evolution.
Course Coordinator: Professor Frank Grutzner
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
1 Knowledge at an advanced level of: the origin, structure, function and evolution of genomes and chromosomes; molecular phylogenetics; and the roles of chance, mutation and natural selection in evolution at the molecular genetic level 2 The ability to interpret the primary scientific literature in cytogenetics and evolutionary genetics. 3 Application and integration of knowledge specified in 1 through microscopy techniques and computational methods
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Deep discipline knowledge
- informed and infused by cutting edge research, scaffolded throughout their program of studies
- acquired from personal interaction with research active educators, from year 1
- accredited or validated against national or international standards (for relevant programs)
1, 2, 3 Critical thinking and problem solving
- steeped in research methods and rigor
- based on empirical evidence and the scientific approach to knowledge development
- demonstrated through appropriate and relevant assessment
1, 2, 3 Teamwork and communication skills
- developed from, with, and via the SGDE
- honed through assessment and practice throughout the program of studies
- encouraged and valued in all aspects of learning
1, 3 Career and leadership readiness
- technology savvy
- professional and, where relevant, fully accredited
- forward thinking and well informed
- tested and validated by work based experiences
1, 2, 3 Self-awareness and emotional intelligence
- a capacity for self-reflection and a willingness to engage in self-appraisal
- open to objective and constructive feedback from supervisors and peers
- able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate
Required ResourcesThis course will require the following texts and other resources:
- Copies of scientific papers (supplied by the lecturers)
- Practical manuals (supplied by lecturers)
- Practical Laboratories and computer suites
- Scientific equipment
- Lecture theatres and tutorial rooms
- Access to University Library
- Access to computers and internet
- Students must supply laboratory coat and safety glasses for their own use
Learning & Teaching Activities
Learning & Teaching ModesEvery week, there will be 3 lectures supported by 1 tutorial that developes material covered in lectures and one or two practicals that also develop material covered in lectures.
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.A student enrolled in a 6 unit course, such as this, should expect to spend, on average 24 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities SummaryLectures
Chromosome Structure and Evolution
1. Overview – Chromosome Analysis
2. Centromeres and Telomeres
3. Metaphase and Interphase
5. Histone Code
6. Chromosome Evolution
7. Sex Chromosomes in Monotremes I
8. Sex Chromosomes in Monotremes II
1. Genetic Distance
2. Inferring Trees - UPGMa
3. Inferring Trees – Neighbour-Joining
1. A First Look
2. The Decay of Heterozygosity
3. Mutation & Drift
1. The Rate of Substitution & the Neutral Theory
2. Natural Selection & Genetic Drift
3. Natural Selection & Molecular Evolution
1. Linkage Disequilibrium
2. Two-Locus Selection - Genetic Hitchhiking
3. Two-Locus Selection - Clonal Interference
The Evolution of Sex and Sexes
1. The Evolution of Sex I - Hill Robertson Interference
2. The Evolution of Sex II - The Red Queen Hypothesis
3. The Evolution of Sexes
Senescence, Kin Selection & Genomic Imprinting
1. The Evolution of Senescence
2. Kin Selection
3. Genomic Imprinting
Tutorials and Practicals are coordinated with lectures.
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Task Task Type Weighting Hurdle
Yes or No
Approximate timing of
(week of teaching period)
Quiz 1 Summative 12.5% No 1, 2 Week 3 Quiz 2 Summative 12.5% No 1, 2 Week 6 Theory Examination Summative 25% No 1,2 Week 13 Practical reports Formative & Summative 50% No 1,2, 3 Weeks 1-12
Assessment DetailQuizzes (total of 25%)
Students will complete a total of 2 online quizzes during semester (worth 12.5% each). Quizzes will consist of multiple choice,
true/false, numerical and short answer questions.
Theory Exam (25%)
The final 2-hour theory exam will examine the components in the second half of the semester. It will consist of multiple choice, numerical, short answer and long answer questions.
Practical Reports (50%)
Practical reports will be assigned throughout the semester (Weeks 1-12) with the frequency depending on the specific pracs
SubmissionLate submission of assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
- Academic Support with Maths
- Academic Support with writing and speaking skills
- Student Life Counselling Support - Personal counselling for issues affecting study
- International Student Support
- AUU Student Care - Advocacy, confidential counselling, welfare support and advice
- Students with a Disability - Alternative academic arrangements
- Reasonable Adjustments to Teaching & Assessment for Students with a Disability Policy
- LinkedIn Learning
Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
- Academic Credit Arrangement Policy
- Academic Honesty Policy
- Academic Progress by Coursework Students Policy
- Assessment for Coursework Programs
- Copyright Compliance Policy
- Coursework Academic Programs Policy
- Elder Conservatorium of Music Noise Management Plan
- Intellectual Property Policy
- IT Acceptable Use and Security Policy
- Modified Arrangements for Coursework Assessment
- Student Experience of Learning and Teaching Policy
- Student Grievance Resolution Process
Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student’s disciplinary procedures.
The University of Adelaide is committed to regular reviews of the courses and programs it offers to students. The University of Adelaide therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.