GENETICS 3212 - Gene Expression & Hum Devel Genetics (Biomed) III
North Terrace Campus - Semester 2 - 2017
General Course Information
Course Code GENETICS 3212 Course Gene Expression & Hum Devel Genetics (Biomed) III Coordinating Unit School of Biological Sciences Term Semester 2 Level Undergraduate Location/s North Terrace Campus Units 6 Contact Up to 18 hours per fortnight Available for Study Abroad and Exchange N Prerequisites GENETICS 2510 & GENETICS 2520 or equivalent Incompatible GENETICS 3211, GENETICS 3210 & GENETICS 3520 Restrictions Available to BSc(BiomedSc) students only Course Description The material taught in this courses is organised around the theme of genes ? how genes function and their roles in development and disease. The aim is to give students an appreciation, at an advanced level, of the mechanisms that control gene expression, the genetic determination of developmental pathways, the various types of human genetic mutation that lead to disease and the pathogenic pathways from genotype to phenotype. The practical component of the course will extend students? familiarity with various laboratory and/or analytical techniques used in human, developmental or other areas of genetics. Eligible students will be placed in a research laboratory to perform a project involving both laboratory and scientific literature research or will do a mixture of group laboratory-based small research projects with literature research/essay/oral presentation tasks.
Course Coordinator: Associate Professor Michael Lardelli
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
1 Understanding of the underlying conceptual framework regarding the regulation of genes and how research expands our knowledge in this area 2 Understanding of the underlying conceptualframework regarding how genes control embryo development and how research expands our knowledge in this area 3 Understanding of the underlying conceptual framework regarding human genetics and how research expands our knowledge in this area 4 Comprehension of scientific research data described in peer-reviewed journals 5 Recording of laboratory research notes and analysis and reporting of experimental data 6 The ability to extract relevant information from literature databases and to present it in written or oral form
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Deep discipline knowledge
- informed and infused by cutting edge research, scaffolded throughout their program of studies
- acquired from personal interaction with research active educators, from year 1
- accredited or validated against national or international standards (for relevant programs)
1, 2, 3, 4, 5, 6 Critical thinking and problem solving
- steeped in research methods and rigor
- based on empirical evidence and the scientific approach to knowledge development
- demonstrated through appropriate and relevant assessment
4, 5, 6 Career and leadership readiness
- technology savvy
- professional and, where relevant, fully accredited
- forward thinking and well informed
- tested and validated by work based experiences
4, 5, 6 Self-awareness and emotional intelligence
- a capacity for self-reflection and a willingness to engage in self-appraisal
- open to objective and constructive feedback from supervisors and peers
- able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate
4, 5, 6
Required ResourcesThis course will require the following texts and other resources:
Text for Human Genetics lectures: 'Human Molecular Genetics - 4th Edition' by Strachan
Copies of scientific papers for Gene Regulation and Developmental Genetics aspects of the
course (supplied by the lecturers)
Collaborating research laboratories
Practical manuals (if doing genetics/molecular biology laboratory practical work. These are supplied by lecturer/s running each practical)
Practical Laboratories (if doing the practical)
Lecture theatres and tutorial rooms
Access to University Library
Access to computers and internet including a portable internet-capable device during workshops
Students must supply laboratory coat and safety glasses for their own use
Learning & Teaching Activities
Learning & Teaching ModesThis course will be delivered by the following means:
“Pre-workshop” material in the form of pre-recorded lectures or assigned reading material etc. 10 hours per week (includes revision of delivered material.)
4 workshops of 1 hour each per week. Each week will include one 20 minute in-workshop summative test.
72 hours of laboratory/other practical work per semester.
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.The information below is provided as a guide to assist students in engaging appropriately with the course requirements.
A student enrolled in a 6 unit course, such as this, should expect to spend, on average 24 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities Summary
Week Type of Learning Activity Topic 1 Pre-Workshop Material Developmental Neurogenetics Workshop Developmental Neurogenetics Practical Placement or Developmental Genetics Practical 2 Pre-Workshop Material Developmental Neurogenetics Workshop Developmental Neurogenetics Practical Placement or Developmental Genetics Practical 3 Pre-Workshop Material Developmental Neurogenetics Workshop Developmental Neurogenetics Practical Placement or Developmental Genetics Practical 4 Pre-Workshop Material Developmental Genetics Workshop Developmental Genetics Practical Placement or Developmental Genetics Practical 5 Pre-Workshop Material Regulation of Gene Expression / Epigenetics Workshop Regulation of Gene Expression / Epigenetics Practical Placement or Focus Genetic Disease literature review 6 Pre-Workshop Material Regulation of Gene Expression / Epigenetics Lecture Regulation of Gene Expression / Epigenetics Practical Placement or Focus Genetic Disease literature review 7 Pre-Workshop Material Regulation of Gene Expression / Epigenetics and Cancer Genetics Workshop Regulation of Gene Expression / Epigenetics and Cancer Genetics Practical Placement or Focus Genetic Disease literature review 8 Pre-Workshop Material Plant Developmental Genetics Workshop Plant Developmental Genetics Practical Placement or essay on current treatments and future treatment options/possibilities Mid Semester Break 9 Pre-Workshop Material Human Genetics Workshop Human Genetics Practical Placement or oral presentation of a case study of the focus genetic disease 10 Pre-Workshop Material Human Genetics Workshop Human Genetics Practical Placement or oral presentation of a case study of the focus genetic disease 11 Pre-Workshop Material Human Genetics Workshop Human Genetics Practical Placement or oral presentation of a case study of the focus genetic disease 12 Pre-Workshop Material Human Genetics Workshop Human Genetics Practical End of Placement 13* Pre-Workshop Material Workshop
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment task Type of assessment Percentage of total
assessment for grading purposes #
Yes or No #
Outcomes being assessed / achieved In-Workshop Tests Formative/Summative 15% No 1, 2, 3, 4 Final Examination Summative 40% No 1, 2, 3, 4 For laboratory placement: Literature review Formative/Summative 15% No 3, 4, 6 Research report Summative 20% No 1/2/3, 4, 5 ( “/” = “or” ) Supervisor assessment Summative 10% No 4, 5 For Focus Genetic Disease work: *Developmental Genetics Laboratory Practical Summative/Formative 15% No 2, 4, 5 *Literature Review (~2,500 words) on a particular ("Focus") Genetic Disease Formative/Summative 10% No 3, 4, 6 *Essay (~1,500 words) on current treatments and future treatment options/ possibilities for the Focus Genetic Disease Summative/Formative 10% No 3, 4, 6 Oral presentation, 10 minutes, on a case study of the Focus Genetic Disease Summative/Formative 10% No 3, 4, 6
*The order in which the above four practical components will be conducted may vary from year to year.
For students doing the laboratory placement:
Literature review for laboratory placement project (15% of course grade, Learning objectives 3,4,6) ~2,500 words and fully referenced on the background to the laboratory project. This is due at the end of the 8th week of the semester. (Formative and summative assessment)
The course convenor will call for all placement laboratory hosts to interview their students at the end of week 5 to provide feedback to them about how they are progressing in their laboratory work and to discuss progress in writing of the literature review. (Formative assessment, no grade given.)
Research Report on laboratory placement project (20% of course grade, Learning objectives 1/2/3, 4, 5 [“/” = “or” ]). ~2,000 words (plus figures) describing and discussing the research project results. This is due at the end of the semester. (Summative assessment)
Supervisor assessment (10% of course grade) of general approach to laboratory work and the skills displayed in the laboratory. (Summative assessment, Learning objectives 4,5)
For students doing Focus Genetic Disease work:
4 weeks (6 x 4 hour sessions) of Developmental Genetics laboratory practical work (15% of course grade, summative assessment and formative assessment, Learning objectives 2,4,5.)
Literature review of the focus genetic disease (i.e. of a particular genetic disease, 10% of course grade) ~2,500 words and fully referenced on the background to the focus genetic disease. (Summative and formative assessment, Learning objectives 3,4 6)
Essay on current treatments and future treatment development options/possibilities for the focus genetic disease (10% of course grade, summative and formative assessment, Learning objectives 3,4 6)
Oral presentation (Powerpoint) of a case study of the focus genetic disease (10% of course grade, summative and possibly formative assessment*, Learning objectives 3,4 6)
For all students:
Examinations in workshops (15% of course grade, Learning Objectives 1, 2, 3). The final third of one workshop session per week (any of the four workshop sessions per week) will be devoted to answering a series of questions assessing material in that and previous workshops and the pre-workshop material. This will test and reinforce students’ understanding of the course material. To avoid problems with students occasionally missing workshops, students’ final accumulated mark for these examinations will be made up of their best 8 scores (from the possible 12 examinations). (Formative and summative assessement.)
Final examination (40% of course grade). This will be a three hour examination assessing any/all theoretical aspects of the course. The examination includes compulsory areas but also a limited choice of questions within each compulsory area.
SubmissionSubmission of Developmental Genetics Practical workbooks is into the submission box at the front desk of the Molecular Life Sciences Building. Submission of other essays is via MyUni and will include checking for plagiarism by Turnitin. Details on submission are provided in the Course Handbook and/or Practical manuals etc.
Late submission of assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
- Academic Support with Maths
- Academic Support with writing and speaking skills
- Student Life Counselling Support - Personal counselling for issues affecting study
- International Student Support
- AUU Student Care - Advocacy, confidential counselling, welfare support and advice
- Students with a Disability - Alternative academic arrangements
- Reasonable Adjustments to Teaching & Assessment for Students with a Disability Policy
Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
- Academic Credit Arrangement Policy
- Academic Honesty Policy
- Academic Progress by Coursework Students Policy
- Assessment for Coursework Programs
- Copyright Compliance Policy
- Coursework Academic Programs Policy
- Elder Conservatorium of Music Noise Management Plan
- Intellectual Property Policy
- IT Acceptable Use and Security Policy
- Modified Arrangements for Coursework Assessment
- Student Experience of Learning and Teaching Policy
- Student Grievance Resolution Process
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