MICRO 2505 - Immunology & Virology II (Biotechnology)
North Terrace Campus - Semester 2 - 2018
General Course Information
Course Code MICRO 2505 Course Immunology & Virology II (Biotechnology) Coordinating Unit School of Biological Sciences Term Semester 2 Level Undergraduate Location/s North Terrace Campus Units 3 Contact Up to 5 hours per week Available for Study Abroad and Exchange N Prerequisites BIOLOGY 1101/1101ND or BIOLOGY 1401, & BIOLOGY 1201 or BIOLOGY 1202 Incompatible MICRO 2501, MICRO 2503, MICRO 2003B or equivalent Assumed Knowledge MICRO 2504, MICRO 2002 or MICRO 2004 Restrictions Available to B Sc (Biotechnology) students only Course Description This course introduces Immunology and Virology and is complementary to Microbiology II and equivalent courses. An integrated approach is used to study the mechanisms by which our immune system deals with pathogens. Emphasis is also given to the fundamental roles of Immunology and Virology in Biotechnology. Topics covered in the Immunology section comprise innate and adaptive immunity, including T and B cell development, cell mediated and humoral immunity; receptors and cytokines; inflammatory responses; tolerance and autoimmunity; immunity to intra- and extra-cellular organisms such as bacteria, viruses and macroparasites. Topics covered in the Virology section include: information on structure, replication and classification of eukaryotic viruses; virus-host interactions; epidemiology of virus infections; virus vaccines, antiviral drugs and viral diagnostics. Students enrolled in this course will attend one or more of Practicals A, B and C. Refer to Current Students Online Enrolment information at www.sciences.adelaide.edu.au for further information.
Course Coordinator: Dr Christopher Wong
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning OutcomesThe anticipated knowledge, skills and attitude to be developed by the student are:
1 The basic replication strategies of viruses and the fundamentals of interactions between viruses and the host; 2 The role and importance of innate and adaptive immunity to host defence against micro-organisms; 3 The functions and properties of different cell types and organs that comprise the immune system; 4 The processes involved in immune cell development; 5 The assembly and expression of antigen receptor molecules during lymphocyte development; 6 The cellular interactions and activation of immune cells in response to foreign antigen and cytokines; 7 The generation of immune memory and tolerance; 8 Antibody structure and how this relates to antibody functions; 9 The importance of MHC molecules in activation of adaptive immunity; 10 The complement system & Hypersensitivity reactions
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Deep discipline knowledge
- informed and infused by cutting edge research, scaffolded throughout their program of studies
- acquired from personal interaction with research active educators, from year 1
- accredited or validated against national or international standards (for relevant programs)
Learning & Teaching Activities
Learning & Teaching ModesLectures
An average of three lectures per week which are recorded for MyUni
An average of one tutorial per week
An average of 20 hours per semester
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities Summary
Week Topic Lecturer Week 1 Animal Viruses – Classification and Structure Dr. Mohammed Alsharifi Virus Infection of Single Cells Dr. Mohammed Alsharifi Replication of RNA Viruses Dr. Mohammed Alsharifi Week 2 Replication of DNA Viruses Dr. Mohammed Alsharifi Virus-Host Interactions - Transient Infections Dr. Mohammed Alsharifi Virus-Host Interactions - Persistent Infections Dr. Mohammed Alsharifi Week 3 Epidemiology of Virus Infections Dr. Mohammed Alsharifi Control of Virus Infections Dr. Mohammed Alsharifi Diagnosis of Virus Infections Dr. Mohammed Alsharifi Week 4 Innate Immunity Dr. Iain Comerford Cells & Tissues Involved in Mounting Immune Responses I Dr. Iain Comerford Cells & Tissues Involved in Mounting Immune Responses II Dr. Iain Comerford Week 5 Complement Dr. Chris Wong Antibody: Structure and Function Dr. Chris Wong No lecture Week 6 No lecture No lecture No lecture Week 7 Mid-Term Test (50 min) Mechanisms of Humoral Immunity I Dr. Chris Wong Mechanisms of Humoral Immunity II Dr. Chris Wong Week 8 Antibody Technology Dr. Chris Wong Antigen Processing and Presentation Dr. Iain Comerford The Roles of T Cells: Help to B cells, CMI and Memory Dr. Iain Comerford Mid Semester Break Week 9 Labour Day Holiday Cytokines & Receptors in the Immune Sys I Dr. Iain Comerford Cytokines & Receptors in the Immune Sys II Dr. Iain Comerford Week 10 Lymphocyte Development & Differentiation I Prof. Shaun McColl Lymphocyte Development & Differentiation II Prof. Shaun McColl Immunological Tolerance Prof. Shaun McColl Week 11 Autoimmunity Prof. Shaun McColl Immunodeficiences Prof. Shaun McColl Hypersensitivity Reactions Pt 1 Dr. Olivier Fahy Week 12 Hypersensitivity Reactions Pt 2 Dr. Olivier Fahy No lecture No lecture
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Task Task Type Hurdle Weighting Learning Outcome Practicals Summative
20% Tutorials Formative and Summative No 20% Mid-Term Test Summative No 20% End of Semester Exam Summative No 40%
Assessment DetailThe assessment methods used for this course are designed to address a number of the B. Sciences graduate attributes. The indicators provided were reviewed and where appropriate incorporated into the following assessment components, which are:
Students are required to participate and complete the MBS Practical A/B/C.
Students enrolled in this course will attend one or more of Practicals A, B and C offered by the School of Molecular and Biomedical Science. Refer to Current Students Online Enrolment information at www.sciences.adelaide.edu.au for further information.
The tutorials are designed as both summative and formative assessments.
The summative assessment is an MCQ/SAQ test held during the first 10 min of the tutorial. Then for the remaining 40 min, students will discuss tutorial questions (released the week before) pertaining to concepts taught in preceeding lectures (formative assessment).
Of 8 tutorials that students will be attending, 6 will be assessed and the best 5 will be taken into account in the final mark. The remaining 2 tutorials will be non-assessed revision tutorials.
Mid-Term Test (20%)
This is a 50 min summative assessment that will be held during a nominated lecture time slot. Students will be tested on their knowledge and understanding of concepts taught in Virology and Immunology. The assessment will be marked and returned to the the students as feedback.
End of semester examination (40%)
This is a 2 h summative assessment which comprehensively tests the learning outcomes of the Immunology and Virology component of the course. Students will be tested on their knowledge and understanding of the content taught since the beginning of this course.
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that the assignment is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days late or more without an approved extension can only receive a maximum of 50% of the marks available for that assignment.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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This section contains links to relevant assessment-related policies and guidelines - all university policies.
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