ANAT SC 2500 - Cells and Tissues II
North Terrace Campus - Semester 1 - 2014
General Course Information
Course Code ANAT SC 2500 Course Cells and Tissues II Coordinating Unit Anatomy and Pathology Term Semester 1 Level Undergraduate Location/s North Terrace Campus Units 3 Contact Up to 6 hours per week Assumed Knowledge BIOLOGY 1101 & BIOLOGY 1201 or 1202 Course Description Cells and Tissues II considers the structure and function of cells and tissues of the mammalian body. Study of ultrastructural characteristics of the typical mammalian cell is followed by consideration of the structure of tissues, organs and systems. The features of the cells, their arrangement and their intercellular products are considered with emphasis on the relationship between microscopic structure and function. Human examples are mainly used with some material from other mammalian species. Routine techniques used for the study of cells and tissues at the light and electron microscopic levels as well as the principles of microscopy are presented early in the course. Practicals have a problem-solving approach and illustrate topics covered in lectures. Tutorials form a large component of the continuous assessment and give students ongoing feedback information on their progress in the course. Students also participate in an oral presentation and written, referenced summary on a topic in structural cell biology.
Course Coordinator: Dr Julie HaynesCourse Coordinator: Dr Julie Haynes
Phone: +61 8 8313 5769
Location: Room N127, Level 1, Medical School North
Lecturer: Dr Jeff Trahair
Phone: +61 8 8313 5484
Location: Room N118, Level 1, Medical School North
Lecturer: Dr Eleanor Peirce
Phone: +61 8 8313 5192
Location: Room N131b, Level 1, Medical School North
Phone: +61 8 8313 1066
Location: Level 4, Medical School South
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
1 Demonstrate an understanding of the structure and function relationships of cells, tissues, and selected components of the body systems 2 Demonstrate a knowledge of routine tissue processing and causes of artefacts, recognise and interpret the normal appearance and functional status of cells and tissues at the light and electron microscopic levels, and inter-relate two-dimensional histological sections with three-dimensional body structure. 3 Demonstrate competency in using scientific electronic data bases to collect, process and analyse scientific information 4 Demonstrate competency in compiling scientific information for delivering an oral presentation and writing a scientific summary on a histopathological topic 5 Demonstrate competency in engaging in group work activities
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Knowledge and understanding of the content and techniques of a chosen discipline at advanced levels that are internationally recognised. 1-2 The ability to locate, analyse, evaluate and synthesise information from a wide variety of sources in a planned and timely manner. 2-5 An ability to apply effective, creative and innovative solutions, both independently and cooperatively, to current and future problems. 1-5 Skills of a high order in interpersonal understanding, teamwork and communication. 3-5 A proficiency in the appropriate use of contemporary technologies. 2-4 A commitment to continuous learning and the capacity to maintain intellectual curiosity throughout life. 3-4 An awareness of ethical, social and cultural issues within a global context and their importance in the exercise of professional skills and responsibilities. 1, 4, 5
Required ResourcesCells and Tissues Manual
Students are provided with a hard copy of the Cells and Tissues manual in the first practical session. A pdf version is also available on MyUni. The manual has essential information relating to the course and notes for all the practical and tutorial sessions.
Equal First Choices
Ross, MH, and Pawlina, W. (2011) Histology: A Text and Atlas, 6th ed. Lippincott, Williams and Wilkins, Philadelphia
Mescher, AL. (2013) Junqueira’s Basic Histology, 13th ed. Mc Graw Hill, New York.
(Recent, earlier editions of both books are also suitable)
Both books are available at Unibooks, Union Building, University of Adelaide http://www.unibooks.com.au
or Encompass Books, Shop 20, Renaissance Arcade, http://www.encompassbooks.com.au
Recommended ResourcesHistology Text
Kerr, JB. (2010) Functional histology, 2nd ed. Mosby Elsevier, Sydney
Young B, Woodford P, O’Dowd G. (2014) Wheater’s Functional Histology, 6th ed. Churchill Livingstone, London.
Kierszenbaum AL, Tres L. (2012) Histology and Cell Biology, 3rd ed. Mosby Elsevier, Philadelphia
Other Reference Textbooks and Sources
Textbooks on Cellular Biology (eg. Molecular Biology of the Cell, Alberts et al)
Anatomy and Physiology texts (eg. Principles of Anatomy and Physiology, Tortora and Derrickson)
Physiology texts (eg. Human Physiology, Sherwood) etc. will also be very helpful BUT will not be a complete replacement for the recommended texts.
It is assumed that students will also obtain information from scientific journals and specialised books online or from the Barr Smith Library.
Online LearningAll the learning and teaching resources for lectures, practicals and tutorials are available on MyUni, as well as assignments, assignment coversheets, additional images for each practical, answers to tutorials and practical questions, and question papers for past exams and mid-semester tests. Recordings of lectures are also available for most lectures on MyUni.
Learning & Teaching Activities
Learning & Teaching ModesLectures, tutorials, practicals, and workshops are the formats through which the course is presented.
Attendance at practicals and tutorials is compulsory and both require prior preparation. During practicals, students have access to ‘virtual microscopes’ to examine nanozoomed images of histological slides on computers as well as digital images, scanned microscopic images, copies of diagrams, drawings, and micrographs. Practical notes with questions guide students in self-directed learning. Emphasis is placed on relationships between microstructure and function. Some practicals are structured as workshops with students interacting with each other in small groups to complete set tasks.
Most tutorials have set assignments that are submitted a few days prior to each tutorial and are part of the summative assessment. Tutorials include discussion of answers to set questions, presentation of short talks, and review of some practical components. The ongoing feed-back given to students in the assessment of tutorials assists their learning skills and understanding.
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.
35 hours of lectures
24hours of practicals
11 hours of tutorials
30 mins mid semester test
150 mins theory exam
30 mins practical exam
Non Contact Hours
independent reading & revision
16 hours for seminar talk and written summary, slide description project
20 hours for tutorial/ practical assessments
Total workload for semester (12 teaching & 1 non-teaching weeks)
Workload per week for 12 week-semester*
* Expected workload for 3-unit course is 12 hours per week.
Learning Activities SummaryCells and Tissues II (ANAT SC 2500)
L1:Techniques & Microscopy
L2:Cell Structure & Function 1
L3:Cell Structure & Function 2
P1: Microscopy, Tissue Preparation
L4: Basic Tissue Types & Epi-thelial Biology 1
L6:Epithelial Biol 3
Connective Tissue (CT) 1
P2: Cells, Tissue Types
L7: CT Biology 2
L8: CT Biology 3
L9: Nervous Tissues 1
T2: Microscopy, Cells, & Tissue Types
L10: Nervous Tissues 2
L11: Nervous Tissues 3
P4: CT Structure & Function
Part A Topics 1–6
L13: Blood 1
L14: Blood 2
L15: Blood Vessels
P5: Nervous Tissues, Muscle
T4: Epithelium & Connective Tissue
L16: Lymphoid Tissues 1
L17: Lymphoid Tissues 2
L18: Liver Microstructure
P6: Blood Workshop
T5: Nervous & Muscle Tissues
L19: Digestive System 1
L20: Digestive System 2
P7:Vessels, Lymphoid Workshop
part B Topics 7 to 12
L21: Digestive System 3
L22: Respiratory System 1
L23:Respiratory 2 & Renal Sys 1
P8: Digestive System, Liver
T7: Seminars: Part C Topics 13–18
L24: Renal System 2
L25: Cartilage & Bone
L26: Bone & Ossification
P9: Resp. & Renal Systems
T8:Blood, Vessels Lymph & Digestive Systems
L27: Bone Growth & Skin 1
L28: Skin 2
L29: Endocrine Glands 1
P10: Bone, Ossification
T9: Respiratory System, Kidney,
L30: Endocrine Glands 2
L31: Ovary: Follic-ular Dynamics
L32: Uterus: Menstrual Cycle
P11: Skin, Endocrines
T10: Bone, Skin
L33: Male Germ Cell Dynamics
L34:Fertilization to Implantation
P12: Reproductive Systems
L35: Course Summary; What’s next in Anatomy?
Trial Prac Exam
T11: Repro & Endo Systems
JH: Dr Julie Haynes JT: Dr Jeff Trahair EP: Dr Eleanor Peirce
Synopsis of Lectures for Cells and Tissues, 2013
Histological Techniques and Basic Structure of Cells (3 lectures)
Techniques of tissue preparation for light and electron microscopy. Principles of microscopy.
Brief review of membrane structure. Distribution and significance of cellular membranes.
Histological features of interphase, dying, and dividing nuclei.
Relationship between nuclear appearance, cellular activity and cellular identity.
Relationship between cytoplasmic ultrastructure and cellular function.
Cells to Tissues, Epithelium (3 lectures)
Characteristics of four basic tissues (epithelial, connective, muscle, nervous). Structural features of epithelial cells; lateral & free surface modifications, basal laminae. Epithelial types & functions.
Relationship between epithelial ultrastructure & function: eg. absorption, transportation, secretion.
Features of epithelial secretory cells. Relationship between type of secretion and cellular ultrastructure. Myoepithelial cells.
Connective Tissues (3 lectures)
Characteristics and function of the components of connective tissue.
Characteristics and function of different connective tissue types.
Nervous and Muscular Systems (4 lectures)
Divisions of N.S.; neurones and support cells of the nervous system, myelination, structure of nerve fibres, nerves, ganglia, sensory & motor nerve endings.
Introduction to the autonomic nervous system.
Characteristics of contractile tissue, particularly skeletal muscle.
Blood Cells (2 lectures)
Life history of red blood cell, characteristics of anaemia
Life history of leukocytes and platelets, characteristics of anaemia
Vascular System (1 lecture)
Functional histology of vascular tissue.
Lymphoid System (2 lectures)
Lymph circulation, structure-function relationships of lymph nodes.
T and B lymphocytes, features of the thymus, structure-function relationships of the spleen.
Digestive System (4 lectures)
Generic structure of the gastrointestinal tract,
Structural basis of digestion, absorption, barrier/immunity and the regulation and integration of these processes; cellular differentiation and division.
Functional histology of the liver.
Respiratory System (2 lectures)
Microstructure and function of upper respiratory tract.
Functional microstructure of lungs.
Kidneys (1 lecture)
Overview of regions of the kidney; microstructural basis of kidney function.
Cartilage, Bones, Ossification (2 lectures)
Microarchitecture of cartilage and bone
Formation and growth of bones.
Skin (2 lectures)
The structure-function relationships of skin
Endocrine Cells (2 lectures)
General structural biology of endocrines; immunocytochemical identification of endocrine cells.
Characteristics of hypothalamus, pituitary, thyroid, parathyroid, adrenal and pancreatic islets of Langerhans.
Reproductive Systems (4 lectures)
Spermatogenesis and oogenesis; reproductive hormones;
Ovarian and menstrual cycles; fertilization.
Small Group Discovery ExperienceIn Cells and Tissues, the student seminar tutorials engage the students in preparing and presenting a short talk and associated written summary on a given medical sciences topic that has a focus on normal versus abnormal microstructure and function. Students gain confidence in delivering a short scientific presentation and further develop their research and scientific writing skills from first year. One of the unique aspects of the student seminars is to promote the importance of being an active audience member during seminar presentations and individual students are rewarded for asking questions about the topic at the end of each presentation.
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Task Assessment Type Weighting Learning Outcome(s) being addressed Final theory exam Summative 40% 1-2 Final practical exam Summative 8% 1-2 Tutorial & practical assignments Formative and Summative 26% 1-3 Mid-semester test Formative and Summative 6% 1-2 Oral and written seminar presentations Formative and Summative 10% 1-5 Slide description assignment Formative and Summative 10% 1-2
Assessment Related RequirementsNB. For a student to attain a pass in Cells and Tissues II:
1. At least 45% must be attained for the combined theory and practical examinations.
2.All components of the assessment must be attempted or else a grade of fail will be recorded.
Student seminars, tutorials and practicals are compulsory. Students must attend all student seminar sessions and 90% of tutorials and practicals.
Assessment DetailFinal theory exam (40%) & Practical Exam (8%).
This evaluates the individual student’s understanding and knowledge of the contents in the course and reflects the learning outcomes from continuous formative and summative assessment tasks during the semester.
Tutorial and Practical Assignments (26%)
These frequent tasks form almost half of the semester continuous assessment score. All but the worst assignment contribute to this summative component of the assessment. The assignments encourage the students’ continual learning processes, so that they can understand basic principles, introduced early in the course, and progressively incorporate this basic knowledge into more complex concepts as the course progresses. The almost weekly tutorials provide extensive opportunities for formative assessment where students can reflect on the effectiveness of their learning styles and become aware of other successful methods in responding to problems and questions in assignments. This is also achieved when students self-assess or peer assess assignments.
Mid-semester test (6%)
This evaluates student’s individual learning and understanding of the first half of the course and makes them aware of the expected level of knowledge associated with the course.
Student Seminar, scientific oral and written presentations (10%)
This assignment has summative and formative assessment. Students are provided with detailed instructions, guidelines, and copies of the assessment sheet for this component of the assessment. Before the assignment, students analyse examples of very poor and very good written presentations and discuss strategies for producing stimulating oral presentations. The completed assessment sheet with comments is returned to the student.
Slide description assignment (10%).
This assesses the student’s skills in examining a histological section, identifying its components and distinguishing between what cells and structures are theoretically present in a section of an organ and what is actually identifiable in a given histological section. Students who achieve low grades in this assessment have the opportunity to repeat the assignment and consolidate their skills.
SubmissionAnswers to most tutorial assignments must be submitted for assessment in the Cells and Tissues Assignment box that is located on the right side of the corridor, first floor, Medical School North, just around the corner from the lifts and office. by the due date specified on the question paper. For most tutorial assignments, the due date is the Thursday, 4 days prior to the Tuesday tutorial. Cover sheets that must be read, completed, signed, and stapled to each assignment are available next to the assignment box or can be downloaded from MyUni. Practical assignments need to be written on the assignment sheets available on MyUni and completed before the start of the relevant practical sessions whereby they can be submitted for assessment. Turn-around time for assessment of tutorial assignments is less than a week. The assessment of Student Seminars and the Slide Description assignments will be completed and returned to students by the last week of the semester, at the latest.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.PRIMARY EXAMINATIONS
Semester 1 primary exams will be held from late June to early July. The exam timetable is available mid May.
For Cells and Tissues the practical exam will be held on the Thursday of Swot Vac in the computer suites, Barr Smith South, Room 1063.
The theory exam will be held at the Adelaide Showgrounds, Wayville during the examination period.
SEMESTER 1 REPLACEMENT/ ADDITIONAL ASSESSMENT
Details on replacement/ additional assessment can be found at: http://www.adelaide.edu.au/student/exams/supps.html
Students will be advised by email immediately their results are finalised if they become eligible for a replacement/ additional assessment which are offered:
1. On medical grounds, if a doctor’s certificate, produced within a week of the examination is deemed to indicate genuine disability at the time of the final examination.
2. On compassionate grounds for special circumstances with supporting documentation
3. On academic grounds to students who fail, yet obtain at least 40% in the combined theory and practical examination.
The replacement/ additional assessment application form is available at http://www.adelaide.edu.au/student/current/exams/. Students who wish to apply for a replacement/ additional assessment on medical or compassionate grounds must apply through the School of Medical Sciences within 7 days of the occurrence of the condition or circumstances. Where the occurrence falls on the day of the primary exam, students must apply within 5 working days of that date.
Semester 1 replacement/ additional assessments will be held in the last week of the mid-year break.
For Cells and Tissues, the replacement/ additional assessment theory exam is held in the morning in the Bonython Hall, North Tce Campus, University of Adelaide and the practical exam is held in the afternoon of the same day in Barr Smith South, Room 1063, unless otherwise advised.
NB: PLEASE BE AWARE THAT THE REPLACEMENT/ ADDITIONAL ASSESSMENT WILL NOT BE OFFERED AT A VENUE OUTSIDE THE NORTH TERRACE CAMPUS, UNIVERSITY OF ADELAIDE, OR ON A DIFFERENT DAY. If you are planning holidays or journeys interstate or overseas, ensure you have returned to Adelaide ten days before the start of second semester.
Academic replacement/ additional assessment theory and practical exams will count 54%.
Marks for continuous assessment are not redeemable and will count 46%.
NB. Results of medical and compassionate replacement/ additional assessments replace final exam results, even if supplementary results are worse than the final exam results.
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