MICRO 2506 - Medical Microbiology and Immunology II
North Terrace Campus - Semester 1 - 2014
General Course Information
Course Code MICRO 2506 Course Medical Microbiology and Immunology II Coordinating Unit School of Molecular and Biomedical Science Term Semester 1 Level Undergraduate Location/s North Terrace Campus Units 3 Contact Up to 3.5 hours per week Prerequisites MBBS Level I Incompatible MICRO 3003 Assumed Knowledge BIOLOGY 1101 & BIOLOGY 1201 Restrictions Available to Level II MBBS students only Course Description This course is an introduction to basic immunology, virology and microbiology for MBBS Level 2 students. Emphasis is first placed on understanding the fundamentals of these disciplines, with examples relevant to clinical and diagnostic medicine. Topics covered in
Immunology include: Innate immunity; specific humoral effector mechanisms; cells and tissues of the immune system; antigen recognition by T cells; cell-mediated immunity, hypersensitivity; human leukocyte antigen (HLA) polymorphism, transplantation; autoimmunity; immunodeficiency.
Virology include: virus classification, structure and replication; pathogenesis, epidemiology and control of virus infections; respirator, gastrointestinal and sexually transmitted viruses; virus diagnostic methods.
Microbiology include: bacterial structure, classification and growth; mechanisms of gene transfer; diagnotic microbiology; mechanisms of bacterial pathogenesis; sterilisation and disinfection; meningitis and encephalitis; antibiotics and resistance; medical mycology and parasitology
Course Coordinator: Dr Christopher Wong
The full timetable of all activities for this course can be accessed from Course Planner.
Course Learning Outcomes
1 To introduce and describe the classification, structure, classification and physiology of bacteria that infect humans. To understand the importance of pathogenic bacteria in human disease with respect to infections of the respiratory tract, gastrointestinal tract, urinary tract, skin and soft tissue. 2 To learn about the diseases caused by anaerobic bacteria. To introduce basic and molecular techniques employed in diagnostic bacteriology laboratories. To learn about the use of antibiotics and resistant mechanisms encoded in bacteria to neutralise these chemical agents. 3 To show how bacterial-related meningitis, encephalitis and sexually-transmitted diseases are diagnosed, treated and managed. To introduce basic concepts in medical mycology. To introduce bacteria that causes sexually transmitted diseases 4 To learn about non-specific defences provided by the innate immune system, To introduce the cells and tissues of the immune system. To learn about the humoral arm of the adaptive immune response. To learn about the cell-mediated arm of the adaptive immune response. 5 To understand how B and T cells develop . To understand the concept and function of immunological tolerance. To discuss human leukocyte antigen polymorphism in the context of transplantation and autoimmunity. 6 To discuss the mechanisms underlying immunological hypersensitivity reactions 7 To introduce and describe the classification and structure of medically important viruses that infect humans. To understand how virus structure impacts on transmission of viruses by respiratory, faecal-oral, blood-borne and sexual transmission routes. 8 To understand the life cycles of medically important viruses including: poliovirus; hepatitis C virus; influenza A virus; human immunodeficiency virus; hepatitis B virus; herpes simplex virus; varicella zoster virus; gastroenteritis viruses and human papilloma viruses. To describe the factors that contribute to the pathogenesis of medically important viruses. To understand why some viruses cause transient and others cause persistent virus infections. To introduce principles behind the epidemiology and control of virus infections. 9 To understand the clinical relevance of treatments for virus infections including: hepatitis B virus, hepatitis C virus, human immunodeficiency virus, respiratory viruses, human papillomaviruses and gastroenteritis viruses. To introduce basic and molecular techniques employed in diagnostic virology laboratories
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Knowledge and understanding of the content and techniques of a chosen discipline at advanced levels that are internationally recognised. 1-9 The ability to locate, analyse, evaluate and synthesise information from a wide variety of sources in a planned and timely manner. 1-9 An ability to apply effective, creative and innovative solutions, both independently and cooperatively, to current and future problems. 1-9 Skills of a high order in interpersonal understanding, teamwork and communication. 1-9 A proficiency in the appropriate use of contemporary technologies. 1-9 A commitment to continuous learning and the capacity to maintain intellectual curiosity throughout life. 1-9 A commitment to the highest standards of professional endeavour and the ability to take a leadership role in the community. 1-9 An awareness of ethical, social and cultural issues within a global context and their importance in the exercise of professional skills and responsibilities. 1-9
Recommended ResourcesReview of Medical Microbiology and Immunology
by Warren Levinson, 2008, 10th edition
McGraw Hill Lange
Basic Immunology: Functions and Disorders of the Immune System
Abbas & Litchman
3rd Edition - Updated Edition
Learning & Teaching Activities
Learning & Teaching ModesLectures
An average of three lectures per week which are recorded for MyUni
An average of one tutorial per week
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.The information below is provided as a guide to assist students in engaging appropriately with the course requirements.A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required.
This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities SummaryNo lecture
Week Lecture Topic Lecturer Week 1 Revision of the Structure,
Classification and Physiology of bacteria (Chps 1-13)
Dr. Connor Thomas Acute Bacterial Infections of the Resp Tract (Chp 19) Dr. Celia Cooper Bacterial Enteric Infections and Food Poisoning (Chp 18) Dr. Celia Cooper Week 2 Adelaide Cup Holiday Diseases Caused by Anaerobic Bacteria (Chp 14) Dr. Ivan Bastian Acute Bacterial Infections of the Urinary Tract Dr. Gerhard Weldhagen Week 3 Skin and Soft Tissue Infections (Chp 15) Prof. John Turnidge Medical Mycology (Chp 47-50) Dr. Sarah Kidd Sexually Transmitted Disease (Bacterial) Dr. Stephen Kidd Week 4 Acute Non-Viral Infections of the CNS Prof. John Turnidge No lecture No lecture Week 5 No lecture No lecture Theory Test 1 (Refer to Myuni for seating allocations) Week 6 Innate Immunity (Chp 8,57,63) Dr. Chris Wong Cells & Tissues of the Immune System (Chp 58) Prof. Shaun McColl Specific Humoral Effector Mechanisms I (Chp 59) Dr. Chris Wong MID SEMESTER BREAK Week 7 Specific Humoral Effector Mechanisms II (Chp 60) Dr. Chris Wong Antigen Presentation (Chp 61) Prof. Toby Coates The Roles of T Cells: Help to B cells, CMI and Memory (Chp 61) Prof. Shaun McColl Week 8 T Cell Development & Immunological Tolerance (Chp 66) Prof. Shaun McColl Transplantation (Chp 62) Prof. Toby Coates Hypersensitivity Reactions (Chp 65) Dr. Olivier Fahy Week 9 No lecture No lecture Theory Test 2 (Refer to Myuni for seating allocations) Week 10 Pathogenesis of Virus Diseases 1 (Chp 32) Dr. Mohammed Alsharifi Pathogenesis of Virus Diseases 2 (Chp 32) Dr. Mohammed Alsharifi Virus Infections & Immune Evasion Dr. Karla Helbig Week 11 Epidemiology and Control of Virus Infections (Chp 35,36) Dr. Mohammed Alsharifi Human Immunodeficiency Virus Infection (Chp 45) Dr. Amanda Aloia Hepatitis B and C Virus Infections (Chp 41) A/Prof. Michael Beard Week 12 Arbovirus Infections (Chp 42) Dr. Mohammed Alsharifi Respiratory Virus Infections (Chp 39) Dr. Mohammed Alsharifi Virus Gastroenteritis (Chp 40) Dr. Rodney Ratcliff Week 13 Queen's Birthday Holiday No lecture Theory Test 3 (Refer to Myuni for seating allocations)
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Task Task Type Hurdle Weighting Learning Outcome Tutorials Formative
0% e.g. LO2 Theory
Summative No 30% e.g. 1,2,3,4,6 End of Semester Exam Summative No 70%
The assessment methods used for this course are designed to address a number of the MBBS graduate attributes. The indicators provided were reviewed and where appropriate incorporated into the following assessment components, which are:
The tutorials are designed as formative assessments to allow students to clarify concepts taught during preceeding lectures. 2 tutorials will be held for each of the 3 blocks of lectures (Microbiology, Immunology and Virology) making a total of 6 tutorials.
Theory Tests (30%)
These summative assessments (3) will be held at the end of each block of lectures (Microbiology, Immunology and Virology) during nominated lecture time slots. Students will be tested on their knowledge and understanding of the content of each block of lectures. Each test will be a combination of MCQ and/or modified SAQ type questions. The test will be marked and returned to the the students as feedback.
End of semester examination (70%)
This summative assessment comprehensively tests the learning outcomes of the entire theory component of the course. Students will be tested on their knowledge and understanding of the content taught since the beginning of this course.
No information currently available.
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending
Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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