HLTH SC 2108 - Precision Medicine: Disease, Treatment & Prevention

North Terrace Campus - Semester 2 - 2020

A major source of improvements in health outcomes in modern medicine have come from a precision medicine approach. Precision medicine involves the use of biomarkers, genetic information and state-of-the art imaging to ensure that the patient receives the right diagnosis; receives the right medicine for them and at the right dose for the right duration. This course will provide an overview of contemporary issues in pathology and pharmacology and expand on concepts developed in Essential Understanding of Disease and Treatment. Students will learn contemporary concepts in modern pharmacology, including basic pharmacokinetic concepts and drug-drug interactions, precision medicine and modern drug development. They will develop an understanding of the unique pathological and pharmacological factors impacting on different population groups and disease outcomes and how this can be exploited in precision medicine for both disease treatment and prevention.

  • General Course Information
    Course Details
    Course Code HLTH SC 2108
    Course Precision Medicine: Disease, Treatment & Prevention
    Coordinating Unit Medicine
    Term Semester 2
    Level Undergraduate
    Location/s North Terrace Campus
    Units 3
    Contact Up to 3 hours per week
    Available for Study Abroad and Exchange Y
    Prerequisites ANAT SC 1102 or BIOLOGY 1101 or MEDIC ST 1000B
    Incompatible HLTH SC 2103 and HLTH SC 2107
    Assumed Knowledge HLTH SC 2104
    Course Description A major source of improvements in health outcomes in modern medicine have come from a precision medicine approach. Precision medicine involves the use of biomarkers, genetic information and state-of-the art imaging to ensure that the patient receives the right diagnosis; receives the right medicine for them and at the right dose for the right duration. This course will provide an overview of contemporary issues in pathology and pharmacology and expand on concepts developed in Essential Understanding of Disease and Treatment. Students will learn contemporary concepts in modern pharmacology, including basic pharmacokinetic concepts and drug-drug interactions, precision medicine and modern drug development. They will develop an understanding of the unique pathological and pharmacological factors impacting on different population groups and disease outcomes and how this can be exploited in precision medicine for both disease treatment and prevention.
    Course Staff

    Course Coordinator: Dr Ian Musgrave

    Course Timetable

    The full timetable of all activities for this course can be accessed from Course Planner.

    A detailed timetable of lectures and workshops will be available on MyUni.
  • Learning Outcomes
    Course Learning Outcomes
    1. Demonstrate knowledge of contemporary concepts in modern pharmacology, including basic pharmacokinetic concepts and drug-drug interactions, personalised medicine and modern drug development.

    2. Demonstrate basic understanding of unique pathology and pharmacology factors impacting on different population groups and disease outcomes and how this can be exploited in precision medicine.

    3. Describe the multidisciplinary nature of the development and application of new tools in precision medicine.

    4. Outline how modern technologies have changed diagnosis, treatment, disease prevention and patient outcomes.

    5. Describe the basic determinants of individual response to medicines and demonstrate an understanding of how genetics alters therapeutic response to medicines.
    University Graduate Attributes

    This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

    University Graduate Attribute Course Learning Outcome(s)
    Deep discipline knowledge
    • informed and infused by cutting edge research, scaffolded throughout their program of studies
    • acquired from personal interaction with research active educators, from year 1
    • accredited or validated against national or international standards (for relevant programs)
    1-5
    Critical thinking and problem solving
    • steeped in research methods and rigor
    • based on empirical evidence and the scientific approach to knowledge development
    • demonstrated through appropriate and relevant assessment
    5
    Teamwork and communication skills
    • developed from, with, and via the SGDE
    • honed through assessment and practice throughout the program of studies
    • encouraged and valued in all aspects of learning
    1-5
    Career and leadership readiness
    • technology savvy
    • professional and, where relevant, fully accredited
    • forward thinking and well informed
    • tested and validated by work based experiences
    1-5
    Intercultural and ethical competency
    • adept at operating in other cultures
    • comfortable with different nationalities and social contexts
    • able to determine and contribute to desirable social outcomes
    • demonstrated by study abroad or with an understanding of indigenous knowledges
    2, 5
    Self-awareness and emotional intelligence
    • a capacity for self-reflection and a willingness to engage in self-appraisal
    • open to objective and constructive feedback from supervisors and peers
    • able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate
    1-5
  • Learning Resources
    Required Resources
    All specific readings etc will be available on MyUni.
    Recommended Resources
    All specific readings etc will be available on MyUni.
    Online Learning
    The primary means of communication outside of the formal contact hours will be via MyUni. Announcements will be used as the main method of communicating with the student cohort. Course material will be supported by online resources and lecture recordings via MyUni. Material will be sequentially released in line with the teaching and learning activities in each week.

    All online quizzes and CBL tutorial assignments will be completed and submitted online via MyUni and they will be e-marked.
  • Learning & Teaching Activities
    Learning & Teaching Modes
    Lectures will be supported by workshops / large group tutorials to reinforce and further expand or develop material covered in lectures. There will be 2 lectures and 1 workshop/ large group tutorial per week.
    Workload

    The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

    Is a 3 unit course so the total workload (including contact and non-contact) for a 3 unit course is 150 hours.
    Learning Activities Summary
    Lectures will be supported by workshops / large group tutorials to reinforce and further expand or develop material covered in lectures. There will be 2 lectures and 1 workshop/ large group tutorial per week
    Specific Course Requirements
    N/A
    Small Group Discovery Experience
    N/A
  • Assessment

    The University's policy on Assessment for Coursework Programs is based on the following four principles:

    1. Assessment must encourage and reinforce learning.
    2. Assessment must enable robust and fair judgements about student performance.
    3. Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
    4. Assessment must maintain academic standards.

    Assessment Summary


    Assessement task Assessment Type Assessment weighting Hurdle requirement? Learning outcomes assessed
    Online quizzes Formative 0% No 1-5
    CBL tutorial assignments Summative 30% No 1-5
    Mid semester test Summative 25% No 1-5
    Examination Summative 45% Yes 1-5

    Modified arrangements have been made to assessments and the details provided here reflect recent updates:

    All assessments will remain as listed above
    End-of-semester exam will be online
    Assessment Related Requirements
    N/A
    Assessment Detail
    Formative online quizzes: Students will complete three online quizzes over the course duration. These will be multiple choice, true /false, matching questions and provide feedback to students on how they are progressing.

    Mid-Semester test: This will be a 50 min in class test in the same form as the final examination consisting of multiple choice and short answer questions. This test will take place in week 6 and examine content from weeks 1 through to 5.

    Large group tutorials case based (CBL) assignments: 4 assignments of 7.5% each will be based on sessions of CBL. Students will complete a worksheet for assessment based on CBL content. Students will work together in small groups during the tutorial to answer CBL questions and submit individual assessments online via MyUni.

    Examination: A 2 hour exam to be held at the end of semester consisting of multiple choice questions and short answer questions will assess content delivered from weeks 6 – 12. Students must achieve a minimum of 40% for the final examination and reach a final course mark of 50% in order to pass the course. If a student does not achieve the 40% minimum mark for the final examination a redemption examination will be offered.

    Note: Modified arrangements have been made to assessments (see end of Assessment Summary section)
    Submission
    All online quizzes and CBL tutorial assignments will be completed and submitted online via MyUni and they will be e-marked.
    Course Grading

    Grades for your performance in this course will be awarded in accordance with the following scheme:

    M10 (Coursework Mark Scheme)
    Grade Mark Description
    FNS   Fail No Submission
    F 1-49 Fail
    P 50-64 Pass
    C 65-74 Credit
    D 75-84 Distinction
    HD 85-100 High Distinction
    CN   Continuing
    NFE   No Formal Examination
    RP   Result Pending

    Further details of the grades/results can be obtained from Examinations.

    Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

    Final results for this course will be made available through Access Adelaide.

  • Student Feedback

    The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

    SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.

    This will be the first time this course has run so there is no previous SELT feedback. 
  • Student Support
  • Policies & Guidelines
  • Fraud Awareness

    Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student’s disciplinary procedures.

The University of Adelaide is committed to regular reviews of the courses and programs it offers to students. The University of Adelaide therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.