Dr Elizabeth Tran

Dr Elizabeth Tran
  • Qualifications

    2008 PhD in BioScience (Microbiology)
    University of Adelaide
    Thesis "Molecular characterisation of S. flexneri outer membrane protease IcsP"

    2003 Bachelor of Laboratory Medicine (Biomed) with Honours
    University of South Australia
    Thesis "Molecular mechanisms of reduced penicillin susceptibility in Neisseria meningitidis"
    (research conducted at the Women and Children's Hospital, Adelaide)

     

  • Awards & Achievements

    2004 Australian Postgraduate Award Scholarship
    (Australian Commonwealth Government scholarship to study a PhD at the University of Adelaide, 2004 - 2008)

    2003 Terumo Prize for Excellence in Laboratory Medicine with Honours
    (highest aggregate mark in Honours course in the Degree of Bachelor of Laboratory Medicine)

    Dean's Merit List (2000, 2002, 2003)
    (Undergraduate, Bachelor of Biomedical science)

     

  • Publications

    Tran, E. N. H., Day, C. J., McCartney, E., Poole, J., Tse, E., Jennings, M. P., & Morona, R. (2020). Shigella flexneri targets human colonic goblet cells by O antigen binding to Sialyl-Tn and Tn antigens via glycan-glycan interactions. ACS Infectious Diseases, 6(10), 2604-2615.

    Qin, J., Doyle, M. T., Tran, E. N. H., & Morona, R. (2020). The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function. PloS one, 15(1), e0227425.

    Tran, E. N., Day, C. J., Poole, J., Jennings, M. P., & Morona, R. (2020). Specific blood group antibodies inhibit Shigella flexneri interaction with human cells in the absence of spinoculation. Biochemical and Biophysical Research Communications, 521(1), 131-136.

    Helbig, K. J., M. Y. Teh, K. M. Crosse, E. A. Monson, M. Smith, E. N. Tran, A. J. Standish, R. Morona and M. R. Beard (2019). "The interferon stimulated gene viperin, restricts Shigella flexneri in vitro." Sci Rep 9(1): 15598.

    Day, C. J., E. N. Tran, E. A. Semchenko, G. Tram, L. E. Hartley-Tassell, P. S. Ng, R. M. King, R. Ulanovsky, S. McAtamney, M. A. Apicella, J. Tiralongo, R. Morona, V. Korolik and M. P. Jennings (2015). "Glycan:glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells." Proc Natl Acad Sci U S A 112(52): E7266-7275.

    Papadopoulos, M.*, E. N. Tran*, G. L. Murray and R. Morona (2016). "Conserved transmembrane glycine residues in the Shigella flexneri polysaccharide co-polymerase protein WzzB influence protein-protein interactions." Microbiology 162(6): 921-929. (*Co-first authors)

    Standish, A. J., M. Y. Teh, E. N. H. Tran, M. T. Doyle, P. J. Baker and R. Morona (2016). "Unprecedented Abundance of Protein Tyrosine Phosphorylation Modulates Shigella flexneri Virulence." J Mol Biol 428(20): 4197-4208.

    Chang, C. W., E. N. Tran, D. J. Ericsson, L. W. Casey, T. Lonhienne, F. Benning, R. Morona and B. Kobe (2015). "Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri." PLoS One 10(9): e0138266.

    Tran, E. N., S. R. Attridge, M. Y. Teh and R. Morona (2015). "Shigella flexneri cell-to-cell spread, and growth and inflammation in mice, is limited by the outer membrane protease IcsP." FEMS Microbiol Lett 362(12): fnv088.

    Doyle, M. T., E. N. Tran and R. Morona (2015). "The passenger-associated transport repeat promotes virulence factor secretion efficiency and delineates a distinct autotransporter subtype." Mol Microbiol 97(2): 315-329.

    Nath, P., E. N. Tran and R. Morona (2015). "Mutational analysis of the Shigella flexneri O-antigen polymerase Wzy: identification of Wzz-dependent Wzy mutants." J Bacteriol 197(1): 108-119.

    Tran, E. N., M. Papadopoulos and R. Morona (2014). "Relationship between O-antigen chain length and resistance to colicin E2 in Shigella flexneri." Microbiology 160(Pt 3): 589-601.

    Tran, E. N., M. T. Doyle and R. Morona (2013). "LPS unmasking of Shigella flexneri reveals preferential localisation of tagged outer membrane protease IcsP to septa and new poles." PLoS One 8(7): e70508.

    Tran, E. N. and R. Morona (2013). "Residues located inside the Escherichia coli FepE protein oligomer are essential for lipopolysaccharide O-antigen modal chain length regulation." Microbiology.

    George, D. T., D. P. Stephenson, E. Tran, R. Morona and N. K. Verma (2013). "Complete Genome Sequence of SfII, a Serotype-Converting Bacteriophage of the Highly Prevalent Shigella flexneri Serotype 2a." Genome Announc 1(5).

    Teh, M. Y., E. N. H. Tran and R. Morona (2012). "Absence of O antigen suppresses Shigella flexneri IcsA autochaperone region mutations." Microbiology 158: 2835-2850.

     

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Entry last updated: Friday, 15 Jan 2021