Professor Michelle Lane

Professor Michelle Lane
 Position Professor
 Org Unit Paediatrics and Reproductive Health
 Telephone +61 8 8313 8176
 Location Floor/Room WS5060.01 ,  Adelaide Health and Medical Sciences ,   North Terrace
  • Biography/ Background

    Our Research Group studies the how the oocyte, sperm contribute to the development of the early embryo and how this programs the development of the pregnancy and affects offspring. Using state of the art techniques we are unravelling the biochemical and molecular basis for how a healthy embryo is made. In particular we ae focussing on epigenetic mechanisms including methylation and microRNAs. We also have an interest in embryonic stem cells.

    We are at the fore-front of developing fundamental knowledge in oocyte development, spermatogenesis and embryogenesis to both develop new treatment therapies.

    We also have a vast translational research program where we use this fundamental knowledge to improve IVF treatment for infertile couples.  We work closely with world-leading IVF units Repromed and Monash IVF. We have several patents and have developed several new treatment regimes for IVF patients including the formation of sequential media and blastocyst development, vitirification and in metabolic assessment of embryos.

    Her research group is currently active in understanding how lifestyle factors such as obesity and ageing impact on oocytes, sperm and embryos.


    Michelle is an NHMRC Research Fellow, an inaugural Fellow of Reproductive Biology of the SRB, and in 2012 and 2013 her group has one several prizes at International meetings.

    She received her PhD in 1996 and has published over 150 peer-reviewed papers, reviews and book chapters. She is internationally recognised for her work in understanding the biology of gametes and embryos and her team are frequently invited to give talks both nationally and internationally.

  • Teaching Interests

    Our group is very active in student teaching. 

    We have several Honours and PhD students in our lab, and graduates from our lab are dotted around the world and Australia continuing to develop their science careers.

    • summer scholarships
    • Honours students
    • PhD students

    Current available PhD projects involve:

  • Epigenetic basis of perturbed sperm function caused by obesity
  • Methods to revive an aged egg to improve IVF outcomes.
  • Understanding the role of microRNA in fertilization and embryo development.