Dr Tim Sadlon
|Position||Affiliate Senior Lecturer|
|Org Unit||Women's and Children's Health|
|Telephone||+61 8 8161 7244|
WCH - Clarence Rieger Building
Womens & Childrens Hospital
I am a molecular biologist studying human regulatory T cells (the policemen of the immune system). There is growing evidence that defects in Treg cells contribute to autoimmune diseases but the molecular nature of these defects remain largely unknown. Using genome-wide approaches, ChIP, iCLIP and chromosome conformation capture I aim to identify genes that drive Treg cell formation and function in healthy individuals. This will provide us with the framework to investigate how this regulation can become disrupted in autoimmune disease. This knowledge in turn will lead to the development of novel cell and drug based therapies and diagnostic biomarkers.
Bachelor of Science Degree, 1987. University of Adelaide Adelaide, South Australia
Honours in Biochemistry, 1988. University of Adelaide Adelaide, South Australia
Awarded Ph. D. 1996. Department of Biochemistry, University of Adelaide.
Thesis title: "Regulation of the Rat 5-Aminolevulinate Synthase mRNA: the Role of mRNA Stability."
Supervisor: A/Prof B. K. May
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Entry last updated: Friday, 9 Oct 2020
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