Professor Karen Jones

Professor Karen Jones
 Position William T Southcott Research Fellow
 Org Unit Medical Specialties
 Email karen.jones@adelaide.edu.au
 Telephone +61 8 8313 7821
 Location Floor/Room WS5067.01 ,  Adelaide Health and Medical Sciences ,   North Terrace
  • Biography/ Background

    Prof Jones is a nuclear medicine technologist with over 25 years research experience (she was the first nuclear medicine technologist to be awarded a PhD in Australia). Her research activities have capitalised on the development of state-of-the-art imaging techniques to evaluate gastric motor function and blood flow; this development has been facilitated by the involvement of a number of international collaborators. Her research area is in the under-recognized field of postprandial hypotension.  She has had an ongoing involvement with the pharmaceutical industry and she has been responsible for several investigator-initiated trials. Prof Jones was the top nuclear medicine student in her graduating year at the University of South Australia and has been the recipient of several awards including the ANSTO award for nuclear medicine scientists, Hanson Institute New Investigator award for clinical research and a prestigious NHMRC Achievement Award. Prof Jones has supervised 12 honours, 9 PhD, and 2 Masters students to completion and is a supervisor of 3 current students (1 Honours, 2 PhD). She is an author of 153 original papers, 42 reviews, 7 letters and 9 book chapters and has an h-index of 56 (Google Scholar).

  • Awards & Achievements

    1991 Awarded prize for top Nuclear Medicine student, University of South Australia

    1991 Awarded prize for top Nuclear Medicine student in SA, ANZSNM (SA Branch)

    1999 Recipient of the Australian Nuclear Science and Technology Organisation (ANSTO) Award

    1999 Recipient of the Abbott Laboratories/Roche Products GESA Travel Award

    2002        Recipient of a Juvenile Diabetes Foundation of Australia Travel Award

    2003        Recipient of an NHMRC/Diabetes Australia Career Development Award

    2003        Recipient of the Hanson Institute New Investigator Award for Clinical Research

    2008        Promotion to Associate Professor

    2010        Recipient of an NHMRC Senior Clinical Career Development Award

    2010        Recipient of an NHMRC Achievement Award

    2011        Promotion to Professor

     

  • Research Funding

    Previous funding:

    Prof Jones has previously held grants totaling >$10,000,000 comprising 14 funded NHMRC project grants (2 as CIA: NHMRC ID: APP453650 and NHMRC ID: APP627189), an NHMRC/Diabetes Australia Career Development Award (CDA) (NHMRC ID: APP250453), an NHMRC Senior CDA (NHMRC ID: APP627011), an NHMRC CCRE in Nutritional Physiology, Interventions and Outcomes (NHMRC ID: APP453557) and numerous other grants e.g. from the Diabetes Australia Research Trust (DART), Royal Adelaide Hospital (RAH) Research Foundation, The Rebecca Cooper Medical Foundation, The Vera Ramaciotti Research Foundation, University of Adelaide and UniSA.

    Currently held:

    2017: KL Jones - University of Adelaide Beacon Research Fellow - Project title: Postprandial hypotension - mechanisms and approaches to management.

    2012 - 2018: M Horowitz, G Wittert, P Clifton, C Rayner, I Chapman, C Feinle-Bisset, KL Jones, M Noakes, M Chapman, N Nguyen - NHMRC - CRE Grant - Project title: Translating Nutritional Science to Good Health ($2,500,000)

    2014 - 2017: CK Rayner, M Horowitz, KL Jones - NHMRC - Project Grant - Project title: Modulating gastrointestinal function for control of diabetes ($857,562)

    2014 - 2017: CK Rayner, P Clifton, M Horowitz, KL Jones - NHMRC - Project Grant - Project title: Protein "preloads" to improve postprandial glycaemia in type 2 diabetes ($603,447)

    2017: KL Jones, T Wu, CK Rayner - RAH Research Foundation - Project title: Effects of DPP-4 inhibition with sitagliptin on postprandial blood pressure, glycaemia and incretin hormones in type 2 diabetes - ($47,700)

    2017: C Rayner, M Horowitz, KL Jones, A Deane. University of Adelaide, School of Medicine - RIBG Equipment Grant - Upper gastrointestinal motility and glycaemic control in patients with diabetes and the critically ill. ($38,040)

    2017: KL Jones, L Phillips, C Rayner, A Deane. University of Adelaide, School of Medicine - RIBG Equipment Grant - Mechanisms and management of postprandial hypotension. ($7200)

    2017: L Phillips, C Rayner, N Nguyen, KL Jones, M Horowitz; DART - Impact of pancreatic exocrine insufficiency and pancreatic enzyme replacement therapy on gastric emptying, gut hormone, and glycaemic responses to a meal in type 2 diabetes. ($60,023)

    2017: Y Ali Abdelhamid, KL Jones, M Horowitz, P Kar, L Phillips, T Nguyen, A Deane; - Royal Adelaide Hospital Research Foundation - Clinical Project Grant - Project title: Prevalence, mechanisms and impact of postprandial hypotension in elderly survivors of critical illness. ($49,208)

    2017: KL Jones, T Kimber, L Phillips, C Rayner; - Royal Adelaide Hospital Research Foundation - Clinical Project Grant - Project title: Acute effects of dopaminergic therapy with levodopa/carbidopa on the gastric emptying, blood pressure and superior mesenteric artery blood flow responses to oral glucose in patients with mild to moderate Parkinson's disease. ($30,000)

    2017: JE Stevens, KL Jones, C Rayner, P Kar, A Deane, M Horowitz; - Royal Adelaide Hospital Research Foundation - Clinical Project Grant - Project title: Acute hypoglycaemia and gastric emptying - ‘dose response' and impact on oral drug absorption. ($30,000)

    2017: KL Jones, M Horowitz, CK Rayner S Soenen, R Visvanathan - Royal Adelaide Hospital Research Foundation - 2182 - NHMRC Near miss grant - Project title: Postprandial hypotension - approaches to management. ($57,205)

  • Publications

    LAST 5 YEARS ONLY (from 2012)

    Refereed Publications:

    1. Wu T, Zhao BR, Bound M, Checklin H, Bellon M, Little TJ, Young R, Jones KL, Horowitz M, Rayner CK. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. Am J Clin Nutr 2012;95:78-83.
    2. Ma J, Pilichiewicz AN, Feinle-Bisset C, Wishart JM, Jones KL, Horowitz M, Rayner CK. Effects of variations in duodenal glucose load on glycaemic, insulin, and incretin responses in type 2 diabetes. Diabet Med. 2012; 29:604-8.
    3. Trahair LG, Vanis L, Gentilcore D, Lange K, Rayner CK, Horowitz M, Jones KL. Effects of variations in duodenal glucose load on blood pressure, heart rate, superior mesenteric artery blood flow and plasma noradrenaline in healthy young and older subjects. Clin Sci (Lond). 2012;122:271-9.
    4. Trahair LG, Horowitz M, Rayner CK, Gentilcore D, Lange K, Wishart JM, Jones KL. Comparative effects of variations in duodenal glucose load on glycemic, insulinemic, and incretin responses in healthy young and older subjects. J Clin Endocrinol Metab 2012;97:844-51.
    5. Vanis L, Gentilcore D, Lange K, Gilja OH, Rigda RS, Trahair LG, Rayner CK, Horowitz M, Jones KL. Effects of variations in intragastric volume on blood pressure and splanchnic blood flow during intraduodenal glucose infusion in healthy older subjects. Am J Physiol Regul Integr Comp Physiol 2012;302:R391-9.
    6. Stevens JE, Horowitz M, Deacon CF, Nauck M, Rayner CK, Jones KL.  The effects of sitagliptin on gastric emptying in healthy humans – a randomised controlled study.  Aliment Pharmacol Ther 2012;36:379-90.
    7. Horowitz M, Flint A, Jones KL, Hindsberger C, Rasmussen MF, Kapitza C, Doran S, Jax T, Zdravkovic M, Chapman IM.  Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes. Diabetes Res Clin Pract 2012:97;258-66.
    8. Chang J, Russo A, Bound M, Rayner CK, Jones KL, Horowitz M.  A 25 year longitudinal evaluation of gastric emptying in diabetes mellitus.  Diabetes Care 2012:35;2594-6.
    9. Di Bartolomeo AE, Chapman MJ, V Zaknic A, Summers MJ, Jones KL, Nguyen NQ, Rayner CK, Horowitz M, Deane AM.  Comparative effects on glucose absorption of intragastric and post-pyloric nutrient delivery in the critically ill.  Crit Care 2012:16;R167-173.
    10. Sim J, Deane A, Chapman M, Jones KL, Summers M, Zaknic A, Trahair LG, Goud R, Hausken T, Fraser J, Horowitz M.  Mesenteric blood flow, glucose absorption and blood pressure responses to small intestinal glucose in critically ill patients older than 65 years. Intens Care Med 2013;39:258-66.
    11. Seimon RV, Brennan IM, Russo A, Little TJ, Jones KL, Standfield S, Wishart JM, Horowitz M, Feinle-Bisset C.  Gastric emptying, mouth-to-cecum transit, glycemic, insulin, incretin and energy intake responses to a mixed-nutrient liquid in lean, overweight and obese males. Am J Physiol Endocrinol Metab 2013;304:E294-300.
    12. Wu T, Bound MJ, Standfield SD, Gedulin B, Jones KL, Horowitz M, Rayner CK.  Effects of rectal administration of taurocholic acid on glucagon-like peptide-1 and peptide YY secretion in healthy humans.  Diabetes Obes Metab 2013;15:474-7.
    13. Wu T, Bound MJ, Zhao BR, Standfield SD, Bellon M, Jones KL, Horowitz M, Rayner CK.  Effects of a D-xylose preload with or without sitagliptin on gastric emptying, glucagon-like peptide-1, and postprandial glycemia in type 2 diabetes.  Diabetes Care 2013;36:1913-8.
    14. Ma J, Meyer JH, Checklin HL, Stevens J, Wishart J, Jones K, Horowitz M, Rayner CK.  A randomized trial of enteric-coated nutrient pellets to stimulate gastrointestinal peptide release and lower glycaemia in type 2 diabetes.  Diabetologia 2013;56:1236-42.
    15. Wu T, Bound M, Standfield S, Jones KL, Horowitz M, Rayner CK.  Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans: J Clin Endocrinol Metab 2013;98:E718-22.
    16. Wu T, Bound M, Standfield SD, Bellon M, Young RL, Jones KL, Horowitz M, Rayner CK.  Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans: Diabetes Care 2013;36:e202-3.
    17. Umapathysivam MM, Lee MY, Jones KL, Annink CE, Cousins CE, Trahair LG, Rayner CK, Chapman MJ, Nauck MA, Horowitz M, Deane AM. Comparative effects of prolonged and intermittent stimulation of the glucagon-like peptide 1 receptor on gastric emptying and glycemia. Diabetes 2014;63:785-90.
    18. Trahair LG, Horowitz M, Hausken T, Feinle-Bisset C, Rayner CK, Jones KL. Effects of exogenous glucagon-like-peptide-1 on the blood pressure, heart rate, mesenteric blood flow and glycemic responses to intraduodenal glucose in health older subjects. J Clin Endocrinol Metab 2014;99:E2628-34.
    19. Wu T, Thazhath S, Bound M, Jones KL, Horowitz M, Rayner CK.  Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?  Diabetes Res Clin Pract 2014; 106:e3-6.
    20. Trahair LG, Horowitz M, Marathe CS, Lange K, Standfield S, Rayner CK, Jones KL. Impact of gastric emptying to the glycemic and insulinemic responses to a 75-g oral glucose load in older subjects with normal and impaired glucose tolerance. Physiol Rep 2014;2:e12204-10.
    21. Thazhath S, Wu T, Bound M, Checklin H, Jones KL, Willoughby S, Horowitz M, Rayner CK.  Changes in meal composition and duration affect postprandial endothelial function in healthy humans. Am J Physiol 2014;307:G1191-7.
    22. Marathe CS, Rayner CK, Bound M, Checklin H, Standfield S, Wishart J, Lange K, Jones KL, Horowitz M.  Small intestinal glucose exposure determines the magnitude of the incretin effect in health and type 2 diabetes.  Diabetes 2014;63:2668-75.
    23. Plummer M, Jones KL, Annink C, Cousins C, Meier J, Chapman M, Horowitz M, Deane M. Glucagon-like peptide-1 attenuates the acceleration of gastric emptying induced by hypoglycaemia in health subjects. Diabetes Care 2014;37:1509-15.
    24. Wu T, Ma J, Bound MJ, Checklin H, Deacon CF, Jones KL, Horowitz M, Rayner CK. Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin. Diabetes 2014;63:2776-87.
    25. Wu T, Trahair LG, Bound MJ, Deacon CF, Horowitz M, Rayner CK, Jones KL. Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in patients with type 2 diabetes: a potential role for glucose-dependent insulinotropic polypeptide? Diabet Med 2015;32:595-600.
    26. Trahair LG, Horowitz M, Marathe CS, Lange K, Standfield S, Rayner CK, Jones KL. Impact of gastric emptying to the glycemic and insulinemic responses to a 75-g oral glucose load in older subjects with normal and impaired glucose tolerance. Physiol Rep 2014;2:e12204-10.
    27. Thazhath S, Wu T, Bound M, Checklin H, Jones KL, Willoughby S, Horowitz M, Rayner CK. Changes in meal composition and duration affect postprandial endothelial function in healthy humans. Am J Physiol 2014;307:G1191-7.
    28. Marathe CS, Rayner CK, Bound M, Checklin H, Standfield S, Wishart J, Lange K, Jones KL, Horowitz M. Small intestinal glucose exposure determines the magnitude of the incretin effect in health and type 2 diabetes. Diabetes 2014;63:2668-75.
    29. Plummer M, Jones KL, Annink C, Cousins C, Meier J, Chapman M, Horowitz M, Deane M. Glucagon-like peptide-1 attenuates the acceleration of gastric emptying induced by hypoglycaemia in health subjects. Diabetes Care 2014;37:1509-15.
    30. Wu T, Ma J, Bound MJ, Checklin H, Deacon CF, Jones KL, Horowitz M, Rayner CK. Effects of sitagliptin on glycemia, incretin hormones, and antropyloroduodenal motility in response to intraduodenal glucose infusion in healthy lean and obese humans, and patients with type 2 diabetes treated with or without metformin. Diabetes 2014;63:2776-87.
    31. Kar P, Cousins CE, Annink CE, Jones KL, Chapman MJ, Meier JJ, Nauck M, Horowitz M, Deane AM. Effects of glucose-dependent insulinotropic polypeptide on gastric emptying, glycaemia and insulinaemia during critical illness: a prospective, double blind, randomised, crossover study. Crit Care 2015;19:20.
    32. Ma J, Jesudason D, Stevens J, Jones KL, Clifton P, Horowitz M, Rayner CK. Sustained effects of a protein ‘preload' on glycaemia and gastric emptying over 4 weeks in patients with type 2 diabetes: a randomized clinical trial. Diab Res Clin Prac 2015;108:E31-4.
    33. Plummer M, Jones KL, Trahair L, Meier JJ, Chapman M, Horowitz M, Deane A. Hyperglycemia potentiates the slowing of gastric emptying induced by exogenous GLP-1. Diabetes Care 2015;38:1123-9.
    34. Trahair LG, Horowitz M, Stevens JE, Feinle-Bisset C, Standfield S, Piscitelli D, Rayner CK, Deane AM, Jones KL. Effects of exogenous glucagon-like peptide-1 on blood pressure, heart rate, gastric emptying, mesenteric blood flow and glycaemic responses to oral glucose in older individuals with normal glucose tolerance or type 2 diabetes. Diabetologia 2015;58:1769-78.
    35. Wu T, Thazhath SS, Marathe CS, Bound MJ, Jones KL, Horowitz M, Rayner CK. Comparative effect of intraduodenal and intrajejunal glucose infusion on the gut-incretin axis response in healthy males. Nutr Diabetes. 2015;8:5:e156.
    36. Marathe CS, Bound M, Lange K, Jones KL, Rayner CK, Horowitz M. Ethnic disparities in insulin and glucose-dependent insulinotropic peptide (GIP) responses to intraduodenal glucose in health. Acta Diabetol 2015;63:2668-75.
    37. Trahair LG, Horowitz M, Jones KL. Postprandial hypotension is associated with more rapid gastric emptying in healthy older individuals. J Am Med Dir Assoc 2015;16:521-3.
    38. Marathe CS, Feinle-Bisset C, Pilichiewiczs A, Lange K, Jones KL, Rayner CK, Kahn SE, Horowitz M. The duodenal glucose load impacts the oral disposition index in healthy subjects. Diabet Med 2015;32:1500-3.
    39. Marathe CS, Horowitz M, Trahair LG, Wishart JM, Bound M, Lange K, Rayner CK, Jones KL. Relationships of 'Early' And 'Late' Glycemic Responses With Gastric Emptying During An Oral Glucose Tolerance Test. J Clin Endocrinol Metab 2015;100:3565-71.
    40. Giezenaar C, Trahair LG, Rigda RS, Hutchison AT, Feinle-Bisset C, Luscombe-Marsh ND, Hausken T, Jones KL, Horowitz M, Chapman IM, Soenen S. Lesser suppression of energy intake by orally ingested whey protein in healthy older men compared with young controls. 2015; Am J Physiol Regul Integr Comp Physiol. 2015;309:R845-54.
    41. Hutchison AT, Piscitelli D, Horowitz M, Jones KL, Clifton PM, Standfield S, Hausken T, Feinle-Bisset C, Luscombe-Marsh N. Acute load-dependent effects of oral whey protein on gastric emptying, gut hormone release, glycemia, appetite, and energy intake in healthy men. Am J Clin Nutr 2015;102:1-11.
    42. Thazhath SS, Wu T, Chang J, Khoo J, Kuo P, Checklin H, Bound MJ, Rigda R, Crouch B, Jones KL, Horowitz M, Rayner CK. The glucagon-like peptide-1 (GLP-1) receptor agonist, exenatide, inhibits small intestinal motility, flow, transit and absorption of glucose in healthy subjects and patients with type 2 diabetes: a randomised controlled trial. Diabetes 2016;65:269-75.
    43. Thazhath SS, Bound MJ, Checklin H, Standfield S, Jones KL, Horowitz M, Rayner CK. Administration of resveratrol for five weeks has no effect on GLP-1 secretion, gastric emptying, or glycemic control in type 2 diabetes - a randomised controlled trial. Am J Clin Nutrit 2016;103:66-70. 
    44. Thazhath SS, Bound MJ, Checklin H, Standfield S, Jones KL, Horowitz M, Rayner CK. Effects of intraduodenal hydroxycitrate on glucose absorption, incretin release and glycemia in response to intraduodenal glucose infusion in health and type 2 diabetes - a randomised controlled trial. Nutrition 2016;32:553-9.
    45. Wu T, Little TJ, Bound MJ, Borg M, Zhang X, Deacon CF, Horowitz M, Jones KL, Rayner CK. A protein preload enhances the glucose-lowering efficacy of vildagliptin in Type 2 Diabetes. Diabetes Care. 2016;39:511-7.
    46. Marathe CS, Horowitz M, Trahair LG, Bound M, Checklin H, Lange K, Rayner CK, Jones KL. Effect of duodenal glucose load on blood pressure in type 2 diabetes. Diab Res Clin Prac 2016;113:38-40.
    47. Trahair LG, Kimber TE, Flabouris K, Horowitz M, Jones KL. Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease. World J Gastroenterol 2016;22:4860-7.
    48. Kar P, Plummer MP, Chapman MJ, Cousins CE, Lange K, Horowitz M, Jones KL, Deane AM. Energy-Dense Formulae May Slow Gastric Emptying in the Critically Ill. J Parenter Enteral Nutr. 2016;40:1050-6.
    49. Plummer MP, Kar P, Cousins C, Hausken T, Lange K, Chapman M, Jones KL, Horowitz M, Deane AM. Critical illness is associated with impaired gallbladder emptying as assessed by 3D ultrasound. Crit Care Med 2016;44:e790-6.
    50. Kar P, Plummer MP, Bellomo R, Jenkins AJ, Januszewski AS, Chapman MJ, Jones KL, Horowitz M, Deane AM. Liberal Glycemic Control in Critically Ill patients with Type-2 Diabetes: an Exploratory Study Crit Care Med 2016;44:1695-703.
    51. Rigda R, Trahair LG, Little T, Wu T, Standfied S, Feinle-Bisset C, Rayner CK, Horowitz M, Jones KL. Regional specificity of the gut-incretin response to small intestinal glucose infusion in healthy older subjects. Peptides 2016; 86:126-32.
    52. Wu T, Zhang X, Trahair LG, Bound MJ, Little TJ, Deacon CF, Horowitz M, Jones KL, Rayner CK. Small intestinal glucose delivery affects the lowering of blood glucose by acute vildagliptin in type 2 diabetes. J Clin Endocinol Metab 2016;101:4769-4778.
    53. Thazhath SS, Marathe CS, Wu T, Chang J, Khoo J, Kuo P, Checklin HL, Bound MJ, Rigda RS, Horowitz M, Jones KL, Rayner CK. Acute effects of the glucagon-like peptide-1 receptor agonist, exenatide on blood pressure and heart rate responses to intraduodenal glucose infusion in type 2 diabetes. Diab Vasc Dis Res 2017;1:69-63.
    54. Wu T, Trahair LG, Jones KL, Horowitz M, Rayner CK. Metformin increases the heart rate response to intraduodenal glucose in type 2 diabetes. Diabetes Care (accepted for publication 20 October 2016).
    55. Trahair LG, Marathe CM, Standfield S, Rayner CK, Feinle-Bisset C, Horowitz M, Jones KL. Effects of small intestinal glucose on glycaemia, insulinaemia and incretin hormone release are load-dependent in obese subjects. Int J Obes (accepted for publication 6 Dec 2016).
    56. Marathe CS, Rayner CK, Lange K, Bound M, Wishart J, Jones KL, Kahn SE, Horowitz M. Relationships of the Early Insulin Secretory Response and Oral Disposition Index with Gastric Emptying in Subjects with Normal Glucose Tolerance. Physiol Rep (accepted for publication 15 December 2016).
    57. Wu T, Rayner CK, Jones KL, Horowitz M, Little TJ. Comparative effects of intraduodenal fat and glucose on the gut-incretin axis in healthy males. Clinical Nutrit (submitted).
    58. Trahair LG, Rajendran S, Visvanathan R, Chapman M, Stadler D, Horowitz M, Jones KL. Comparative effects of glucose and water drinks on blood pressure and cardiac function in older subjects with and without postprandial hypotension. J Am Med Dir Assoc (submitted).
    59. Kar P, Jones KL, Plummer MP, Abdelhamid YA, Giersch, Summers MJ, Hatzinikolas S, Heller S, Horowitz M, Deane AM. Antecedent hypoglycemia does not attenuate the acceleration of gastric emptying by hypoglycaemia. Diabetes (submitted).
       

    Reviews/editorials:

    1. Thazhath SS, Jones KL, Horowitz M, Rayner CK.  Diabetic gastroparesis: recent insights into pathophysiology and implications for management.  Expert Rev Gastroenterol Hepatol 2013;7:127-39.
    2. Horowitz M, Rayner CK, Jones KL. Mechanisms and clinical efficacy of lixisenatide for the management of type 2 diabetes.  Adv Ther 2013;30:81-101.
    3. Marathe C, Jones K, Horowitz M, Rayer CK. Glucagon-like peptides 1 and 2 in health and disease: A review. Peptides 2013;44:75-86.
    4. Marathe CS, Rayner CK, Jones KL, Horowitz M. Relationships between gastric emptying, postprandial glycemia and incretin hormones. Diabetes Care 2013;36:1396-405.
    5. Chang J, Rayner CK, Jones KL, Horowitz M. Prognosis of diabetic gastroparesis-a 25-year evaluation.  Diabetes Medicine 2013;30:e185-8.
    6. Stevens J, Horowitz M, Jones KL, Rayner C.  Pathophysiology and pharmacotherapy of gastroparesis - current and future perspectives. Expert Opinion On Pharmacotherapy 2013:14;1171-86.
    7. Trahair LG, Horowitz M, Jones KL.  Postprandial hypotension: a systematic review. J Am Med Dir Assoc 2014;15:394-409.
    8. Rayner CK, Ma J, Jones KL, Clifton PM, Horowitz M.  Protein ‘pre-loads’ in type 2 diabetes: what do we know and what do we need to find out?  Diabetoglogia 2014;57:2603-4.
    9. Phillips L, Rayner CK, Jones KL, Horowitz M. Measurement of gastric emptying in diabetes.  J Diabetes Complicat 2014;28:894-903.
    10. Phillips LK, Deane A, Jones KL, Rayner CK, Horowitz M. Gastric emptying and glycaemia in health and diabetes mellitus. Nat Rev Endocrinol 2015;11:112-28.
    11. Kar P, Jones KL, Horowitz M, Chapman MJ, Deane AM.  Measurement of gastric emptying in the critically ill.  Clin Nutr 2015;34:557-64.
    12. Kar P, Jones KL, Horowitz M, Deane AM.  Management of critically ill patients with type 2 diabetes: the need for personalised therapy. World J Diabetes 2015;6:693-706.
    13. Soenen S, Rayner CK, Horowitz M, Jones KL. Gastric emptying in the elderly. Clin Geriatr Med 2015;31:339-53.
    14. Soenen S, Rayner CK, Jones KL, Horowitz M. The ageing gastrointestinal tract. Current Opinion in Clinical Nutrition and Metabolic Care 2016;19:12-8.
    15. Marathe CS, Rayner CK, Jones KL, Horowitz M. Novel insights into the effects of diabetes on gastric motility. Expert Rev Gastroenterol Hepatol 2016;10:581-93.
    16. Horowitz M, Wu T, Deane AM, Jones KL, Rayner CK. Dipeptidyl peptidase 4 inhibition and the known unknown. Diabetes 2016;65:1-3.
    17. Rayner CK, Jones KL, Wu T, Horowitz M. Gut feelings about diabetes and GLP-1 receptor agonists - lessons to be learnt from studies in functional gastrointestinal disorders. Diabetes Obes Metab (accepted for publication November 2016).
    18. Nguyen TA, Abdelhamid YA, Phillips LK, Chapple LS, Horowitz M, Jones KL, Deane AM. Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients. World J Crit Care Med (accepted for publication January 2017).

     

    Letters:

    1. Rayner CK, Chang J, Jones KL, Horowitz M.  Response to Comment on: Chang et al. A 25-Year Longitudinal Evaluation of Gastric Emptying in Diabetes. Diabetes Care 2012;35:2594-2596.
    2. Marathe CS, Rayner CK, Jones KL, Horowitz M. Letter to the Editor: One-hour postload hyperglycaemia is a strong predictor of type 2 diabetes than impaired fasting glucose. J Clin Endocrinol Metab 2016;101:L33-4.
    3. Marathe CS, Rayner CK, Jones KL, Horowitz M. Reactive hypoglycaemia with seizure following intraduodenal glucose infusion in a patient with type 2 diabetes. Acta Diabetol 2016; Aug 10 ahead of print

     

    Book chapters:

    1. Jones KL, Gentilcore D, Hausken T, Gilja OH. Ultrasonography for evaluation of patients with suspected gastroparesis. In: Gastroparesis: Pathophysiology, Presentation and Treatment. Editors: Parkman HP, McCallum RW, New York: Humana Press. 2012; 131-8.
    2. Rayner CK, Jones KL, Horowitz M. Diabetic Gastroparesis. In: Gastroparesis: Pathophysiology, Presentation and Treatment. Editors: Parkman HP, McCallum RW, New York: Humana Press. 2012; 177-90.
    3. Trahair L, Jones KL.  Ultrasonography of the stomach.  In: Applied aspects of ultrasonography in humans. Editor: Ainslie P, InTech, 2012; 175-190.
    4. Mathias CJ, Jones KL.  Postprandial hypotension in autonomic disorders.  In: Autonomic Failure. A textbook of clinical disorders of the autonomic nervous system.  Editors: Mathias CJ, Bannister R, Oxford University Press, 5th ed. 2013; 354-370.
    5. Rayner CK, Jones KL, Horowitz M.  Diabetes and the Gut.  In: Handbook of gastrointestinal motility and functional disorders.  Editors: Rao SSC, Parkman HP, McCallum RW. 2015; 283-94.

     

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Entry last updated: Friday, 13 Sep 2019

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