Associate Professor Mark Nottle
|Position||Principal Research Fellow|
|Org Unit||Paediatrics and Reproductive Health|
|Telephone||+61 8 8313 4087|
Adelaide Health and Medical Sciences
The Reproductive Biotechnology Group has an international reputation in the general areas of reproductive biology and the development of associated technologies for biomedical and agricultural applications. In collaboration with a number of university, institute and hospital research groups in Australia as well as overseas, current research is focused on developing organ, tissue and cell replacement therapies. This work is funded by various agencies including the Juvenile Diabetes Research Foundation, the National Health and Medical Research Council and industry. Current research is also focussed on the isolation of embryonic stem cells from the pig. These will be used for a range of biomedical and agricultural applications including as a large animal model for human stem cell research.
Smits RJ, Luxford BG, Mitchell M, Nottle MB.
J Anim Sci. 2011 May 24.
Vassiliev I, Vassilieva S, Truong KP, Beebe LF, McIlfatrick SM, Harrison SJ, Nottle MB.
Cell Reprogram. 2011 Jun;13(3):205-13.
Versatile co-expression of graft-protective proteins using 2A-linked cassettes.
Fisicaro N, Londrigan SL, Brady JL, Salvaris E, Nottle MB, O'Connell PJ, Robson SC, d'Apice AJ, Lew AM, Cowan PJ.
Xenotransplantation. 2011 Mar-Apr;18(2):121-30.
Piglets produced from in vivo blastocysts vitrified using the Cryologic Vitrification Method (solid surface vitrification) and a sealed storage container.
Beebe LF, Bouwman EG, McIlfatrick SM, Nottle MB.
Theriogenology. 2011 May;75(8):1453-8.
On the need for porcine embryonic stem cells to produce Gal KO pigs expressing multiple transgenes to advance xenotransplantation research.
Nottle MB, Vassiliev I, O'Connel PJ, d'Apice AJ, Cowan PJ.
Xenotransplantation. 2010 Nov-Dec;17(6):411-2.
Genetic modification of pigs for solid organ xenotransplantation.
Gock H, Nottle M, Lew AM, d'Apice AJ, Cowan P.
Transplant Rev. 2011 Jan;25(1):9-20.
Development of a Mouse Model for Studying the Effect of Embryo Culture on Embryonic Stem Cell Derivation.
Campbell JM, Mitchell M, Nottle MB, Lane M.
Stem Cells Dev. 2011 Mar 17.
In vitro and in vivo characterization of putative porcine embryonic stem cells.
Vassiliev I, Vassilieva S, Beebe LF, Harrison SJ, McIlfatrick SM, Nottle MB.
Cell Reprogram. 2010 Apr;12(2):223-30.
Reproductive responses to daily injections with porcine somatotropin before mating in gilts.
Gatford KL, Grupen CG, Campbell RG, Luxford BJ, Smits RJ, Owens PC, Nottle MB.
J Reprod Dev. 2010 Oct;56(5):540-5.
Development of culture conditions for the isolation of pluripotent porcine embryonal outgrowths from in vitro produced and in vivo derived embryos.
Vassiliev I, Vassilieva S, Beebe LF, McIlfatrick SM, Harrison SJ, Nottle MB.
J Reprod Dev. 2010 Oct;56(5):546-51.
Maternal responses to daily maternal porcine somatotropin injections during early-mid pregnancy or early-late pregnancy in sows and gilts.
Gatford KL, Smits RJ, Collins CL, Argent C, De Blasio MJ, Roberts CT, Nottle MB, Kind KL, Owens JA.
J Anim Sci. 2010 Apr;88(4):1365-78.
Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos.
Beebe LF, McIlfatrick SJ, Nottle MB.
Cloning Stem Cells. 2009 Dec;11(4):477-82.
Gatford KL, De Blasio MJ, Roberts CT, Nottle MB, Kind KL, van Wettere WH, Smits RJ, Owens JA.
J Endocrinol. 2009 Oct;203(1):143-54.
Bagg MA, Nottle MB, Armstrong DT, Grupen CG.
Reprod Fertil Dev. 2009;21(6):796-804
Beebe LF, Vassiliev I, McIlfatrick S, Nottle MB.
J Reprod Dev. 2009 Aug;55(4):373-7.
Beebe L, McIlfatrick S, Grupen C, Boquest A, Harrison S, Faast R, Ashman R, Wengle J, Hamilton H, Nottle M.
Cloning Stem Cells. 2007 Winter;9(4):564-70.
Bagg MA, Nottle MB, Armstrong DT, Grupen CG.
Reprod Fertil Dev. 2007;19(7):797-803.
Nottle MB, Beebe LF, Harrison SJ, McIlfatrick SM, Ashman RJ, O'Connell PJ, Salvaris EJ, Fisicaro N, Pommey S, Cowan PJ, d'Apice AJ.
Xenotransplantation. 2007 Jul;14(4):339-44.
The effect of energy substrate concentration and amino acids on the in vitro development of preimplantation porcine embryos.
Beebe LF, McIlfactrick S, Nottle MB.
Cloning Stem Cells. 2007 Summer; 9(2):206-15.
Faast R, Harrison SJ, Beebe LF, McIlfatrick SM, Ashman RJ, Nottle MB.
Cloning Stem Cells. 2006 Fall;8(3):166-73.
Bagg MA, Nottle MB, Grupen CG, Armstrong DT.
Mol Reprod Dev. 2006 Oct;73(10):1326-32.
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Entry last updated: Thursday, 9 Aug 2018
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